A5101440747- Acute Ischemic Stroke Management
- Glioma Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Brain Metastases and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Nerve Injury and Rehabilitation
- Vascular Procedures and Complications
- Lung Cancer Research Studies
- Surgical Simulation and Training
- Fetal and Pediatric Neurological Disorders
- Central Venous Catheters and Hemodialysis
- Lung Cancer Treatments and Mutations
- Spinal Cord Injury Research
- Renal and Vascular Pathologies
- Sarcoma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Intracranial Aneurysms: Treatment and Complications
- Vascular Anomalies and Treatments
- Venous Thromboembolism Diagnosis and Management
- Moyamoya disease diagnosis and treatment
- Neuroblastoma Research and Treatments
University of California, Irvine
2018-2024
Neurological Surgery
2018-2024
University of California, Irvine Medical Center
2019-2023
Children's Hospital of Orange County
2021-2022
UC Irvine Health
2020-2021
Camden and Campbelltown Hospitals
2019
Liverpool Hospital
2019
UNSW Sydney
2019
Case Western Reserve University
2015-2018
University School
2015-2017
Previous reports have shown that overall incidence of malignant brain and other central nervous system (CNS) tumors varied significantly by country. The aim this study was to estimate histology-specific rates global region assess variation histology age.Using data from the Central Brain Tumor Registry United States (CBTRUS) International Agency for Research on Cancer's (IARC) Cancer Incidence in Five Continents X (including over 300 cancer registries), we calculated age-adjusted (AAIR) per...
Axonal transport deficits in Alzheimer’s disease (AD) are attributed to amyloid β (Aβ) peptides and pathological forms of the microtubule-associated protein tau. Genetic ablation tau prevents neuronal overexcitation axonal caused by recombinant Aβ oligomers. Relevance these findings naturally secreted mechanisms underlying tau’s enabling effect unknown. Here we demonstrate anterograde mitochondria primary neurons from transgenic mice expressing familial AD-linked human precursor protein. We...
Hispanic individuals who suffer from melanoma are diagnosed later and have a worse prognosis. Because the population is one of fastest growing in United States, it important to spread awareness melanoma.The study aimed evaluate whether an online educational video about skin cancer could improve knowledge encourage self-skin examinations (SSE).The authors directed patients survey, which assessed for risk factors prevention. This was followed by 5-minute melanoma. A second survey sent...
Background: Chronic subdural hematomas (cSDH) are increasingly prevalent worldwide with the increased aging population and anticoagulant use. Different surgical, medical, endovascular treatments have had varying success rates. Primary neurosurgical interventions include burr hole drainage of cSDH mini-craniotomies/craniotomies or without fenestration inner membrane. A key assessment failure has been symptomatic recurrence rates which historically ranged from 5 to 30%. Pre-operative...
Ventriculoperitoneal shunts (VPSs) have been the mainstay of treating hydrocephalus since 1950s. However, a reported complication rate reaching nearly 50%. Devices developed that utilize noninvasive thermal transcutaneous diffusion technology. These shunt evaluation devices measure temperature gradients to detect cerebrospinal fluid flow. We assessed utility using technique work up failure in emergency room (ER).This was retrospective case series at single medical center ER. included...
Ethmoid punch sinusotomy (EPS) is a feasible treatment for ethmoid sinusitis in subset of chronic rhinosinusitis (CRS) patients per recent report. This adjunctive work investigates the technical characteristics EPS and determines if measurably alters topical delivery irrigant into sinuses cadaveric model.The sinonasal cavities 10 human cadaver heads were irrigated with solution containing methylene blue radio-opaque contrast prior to following EPS. Procedural distribution assessed by...
Introduction The Thrombolysis in Cerebral Infarction (TICI) score is a predictor ofclinical outcomes following thrombectomy. However, leptomeningeal collateral circulation inlarge vessel occlusion (LVO) also influences the infarct size on postoperative magnetic resonanceimaging (MRI). Near‐infrared spectroscopy (NIRS) offers potential for evaluating collateralmicrocirculation LVO patients. Time‐resolved (TRS), an advanced NIRStechnology, provides absolute optical properties with greater...
BACKGROUND Displacement of a distal catheter ventriculoatrial (VA) shunt is rare complication and can lead to challenging extraction requiring endovascular retrieval the catheter. OBSERVATIONS The authors describe patient in whom VA had become displaced traveled through tricuspid valve into right ventricular outflow tract. LESSONS In this case report, present multidisciplinary approach retrieving from shunt.
Hyperdynamic therapy, also called triple-H is the standard treatment and prophylaxis for aneurysmal-associated vasospasm. In patients who are able to tolerate cardiopulmonary stressors induced by this it of benefit as a modality prevention delayed ischemic neurologic deficit. However, can be cause significant or sequelae. rare cases, associated with posterior reversible encephalopathy syndrome (PRES), secondary prolonged vasopressor hypertensive therapies.We present case patient right-sided...
Introduction: Liquid embolic material (LEM) plays an essential role in the treatment of hemorrhagic stroke caused by arteriovenous malformation or dural fistula. However, currently available non-adhesive LEMs has problem catheter entrapment, and also known to have a cytotoxic effect due organic solvents such as Dimethyl Sulfoxide (DMSO). The New Generation Embolic Material (NGLEM) is clear liquid that immediately forms solid hydrogel cast upon exposure Ca2+ bloodstream, are not required...
Choroid plexus tumors are rare neoplasms that typically found in the lateral ventricles. They have infrequently been reported third ventricle, and treatment strategies varied.The authors described a 6-month-old patient who presented with irritability hypotonia. The was to large tumor ventricle obstructive hydrocephalus. Preoperative angiography revealed feeding artery from right medial posterior choroidal (MPChA). effectively embolized, subsequently received open resection of tumor....