- Molecular Sensors and Ion Detection
- Lipid Membrane Structure and Behavior
- Diet and metabolism studies
- Cardiac Ischemia and Reperfusion
- Hemoglobin structure and function
- Cancer-related gene regulation
- Underwater Vehicles and Communication Systems
- Birth, Development, and Health
- Plasma Applications and Diagnostics
- Particle accelerators and beam dynamics
- Electrohydrodynamics and Fluid Dynamics
- Power Systems and Renewable Energy
- Atherosclerosis and Cardiovascular Diseases
- Microbial Metabolic Engineering and Bioproduction
- T-cell and B-cell Immunology
- Aortic Disease and Treatment Approaches
- Algal biology and biofuel production
- Mitochondrial Function and Pathology
- Photosynthetic Processes and Mechanisms
- Radio Astronomy Observations and Technology
- Systemic Lupus Erythematosus Research
- RNA modifications and cancer
- Smart Grid and Power Systems
- Surfactants and Colloidal Systems
- Nitric Oxide and Endothelin Effects
Utrecht University
2023-2025
University of Alabama at Birmingham
2022-2025
Tianjin University
2016
Chinese Academy of Sciences
2012
South China University of Technology
2011
Membrane lipid oxidation is a universal process that occurs in situations of oxidative stress and encountered numerous physiological pathological situations. Oxidized truncated phospholipids make up large part the products alter membrane properties way can lead to cell death. However, underlying mechanisms are not well understood nor it clear whether environmental factors, such as pH, modulate these effects. Using model membranes, we investigate how individual aldehydes carboxylic acids with...
Oxidative stress in combination with acid has been shown to inactivate a wide spectrum of microorganisms, including multi-resistant bacteria. This occurs e.g. phagolysosomes or during treatment by cold atmospheric pressure plasmas (CAP) and possibly depends on the cell membrane. We therefore explored effects CAP-generated reactive oxygen nitrogen species (RONS) bacterial growth inhibition membranes neutral acidic suspensions. observed that was most efficient when bacteria were treated mix...
This paper summarizes the design scheme and testing results in development of a Ka-band transmitter for future deep space communication systems applications China. The integrated component all-digital baseband data coding modulation Ka band downlink communications is achieved on Xilinx FPGA circuit. schemes PCM/BPSK/PM, NRZ/BPSK SRRC-QPSK are separately chosen corresponding to code rate ranges 16bps~20kbps, 20kbps ~200kbps 200kbps~2Mbps by external control commands circuits. 2W output power...
Background: Cardiac fibrosis is pivotal in heart failure progression, where excessive extracellular matrix (ECM) secretion by activated fibroblasts leads to adverse remodeling and dysfunction. While Wnt/β-catenin signaling influences fibroblast activation cardiac post-MI, its precise regulation remains unclear. Emerging evidence suggests N6-methyladenosine (m 6 A) mRNA methylation's role disease pathology, yet specific contribution post-MI not well understood. Thus, we hypothesized that “...
Intercepting system calls is crucial for tools that aim to modify or monitor application behavior. However, existing call interception on the ARM platform still suffer from limitations in terms of performance and completeness. This paper presents an efficient comprehensive binary rewriting framework, ASC-Hook, specifically designed intercepting platform. ASC-Hook addresses two key challenges architecture: misalignment target address caused by directly replacing SVC instruction with br x8,...
Background: ST-elevation myocardial infarction (STEMI) is the leading cause of heart failure. Ischemia/reperfusion (I/R) injury after revascularization contributes ~50% infarct size, for which there no established clinical treatment. After prompt revascularization, β-hydroxybutyrate (β-OHB) a metabolite that increases during stress. In addition to providing energy, it serves as signaling molecule regulate many protective processes. Increasing β-OHB levels before I/R cardiac protective....
Early life stress (ELS) is defined as childhood adversity such maltreatment (e.g., verbal and physical abuse), sexual abuse, household dysfunction occurring prior to age 18. ELS associated with increased risk of chronic disease poorer health outcomes earlier in adulthood compared those without exposure ELS. SLE an autoimmune most prevalent women high mortality from cardiovascular influenced by environmental factors including psychosocial affects multiple organs the heart. Pericarditis heart...
ELS, such as verbal and physical abuse or maltreatment, is linked to a greater risk ofcardiovascular disease (CVD) in adulthood. Aortic stiffness, an independent predictor of CVD,has been suggested prognostic tool for early detection intervention at-riskpopulations. Several human studies have shown that aortic stiffness (assessed by PWV) isincreased both adults adolescents with ELS. ELS mouse models, maternalseparation weaning (MSEW), show endothelial dysfunction increasedsuperoxide systemic...
Introduction: ST-elevation myocardial infarction (STEMI) is the leading cause of heart failure. Ischemia/reperfusion (I/R) injury after revascularization contributes ~50% infarct size, which we don’t have a clinical therapy. β-hydroxybutyrate (β-OHB) metabolite that increases during stress. In addition to providing energy, it serves as signaling molecule (such histone deacetylase inhibitor) regulate many protective processes. Increasing β-OHB level before I/R cardiac protective. However, has...