Adom Bondzi-Simpson

ORCID: 0009-0002-3290-1009
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About
Contact & Profiles
Research Areas
  • Colorectal Cancer Screening and Detection
  • Global Health Workforce Issues
  • Inflammasome and immune disorders
  • Cardiac, Anesthesia and Surgical Outcomes
  • Esophageal Cancer Research and Treatment
  • Healthcare Policy and Management
  • Primary Care and Health Outcomes
  • Gastric Cancer Management and Outcomes
  • Esophageal and GI Pathology
  • Spine and Intervertebral Disc Pathology
  • Anesthesia and Pain Management
  • Diverticular Disease and Complications
  • Global Health and Surgery
  • Multiple and Secondary Primary Cancers
  • Health Systems, Economic Evaluations, Quality of Life
  • Heme Oxygenase-1 and Carbon Monoxide
  • Colorectal Cancer Surgical Treatments
  • Enhanced Recovery After Surgery
  • Surgical Simulation and Training
  • Simulation-Based Education in Healthcare
  • Innovations in Medical Education
  • Nausea and vomiting management
  • Clinical practice guidelines implementation
  • Health disparities and outcomes
  • COVID-19 and healthcare impacts

Public Health Ontario
2023-2024

University of Toronto
2022-2024

University of Manitoba
2023

University of Calgary
2016-2018

The non-canonical caspase-4 and canonical NLRP3 inflammasomes are both activated by intracellular lipopolysaccharide (LPS), but the crosstalk between these two pathways remains unclear. Shiga toxin 2 (Stx2)/LPS complex, from pathogenic enterohemorrhagic Escherichia coli, activates caspase-4, gasdermin D (GSDMD), inflammasome in human THP-1 macrophages, not mouse macrophages that lack Stx receptor CD77. Stx2/LPS-mediated IL-1β secretion pyroptosis dependent on mitochondrial reactive oxygen...

10.1016/j.celrep.2018.09.071 article EN cc-by-nc-nd Cell Reports 2018-11-01

Days at home after surgery is a promising new patient-centred outcome metric that measures time spent outside of healthcare institutions and mortality. The aim this scoping review was to synthesize the use days in perioperative research evaluate how it has been termed, defined, validated, with view inform future use.

10.1093/bjs/znae278 article EN cc-by British journal of surgery 2024-11-27

Complex lung diseases are among the leading causes of death in Ethiopia. Access to thoracic surgery is limited, and before 2016 no surgeons were trained minimally invasive surgery. A global academic partnership was formed between University Toronto Addis Ababa University. We describe implementation first training program sub-Sahara Africa evaluate its safety.We performed a retrospective cohort analysis open versus upper gastrointestinal procedures at from January June 2021. Baseline...

10.1016/j.xjon.2022.11.015 article EN cc-by-nc-nd JTCVS Open 2022-12-06

To determine the association between residence in racialized neighborhoods with direct healthcare expenditure and days at home (DAH) after moderate to severe traumatic brain injury (TBI).

10.1097/sla.0000000000006584 article EN Annals of Surgery 2024-11-08

I was a first-year resident in downtown Toronto when got page. The emergency physician started the conversation way that makes every resident’s heart sink. “I’ve an interesting one for you.” “Eighty-seven-year-old gentleman with incarcerated hernia. reduced it, but he

10.1503/cmaj.212148 article EN cc-by-nc-nd Canadian Medical Association Journal 2022-09-05

[Voir la version anglaise de l’article ici : www.cmaj.ca/lookup/doi/10.1503/cmaj.212148][1] J’étais un médecin résident première année dans hôpital du centre-ville Toronto quand on m’a joint par téléavertisseur. Au bout fil, l’urgentologue avait ton qui ne laisse pré

10.1503/cmaj.212148-f article FR cc-by-nc-nd Canadian Medical Association Journal 2022-11-20
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