A5069686106- RNA modifications and cancer
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Epigenetics and DNA Methylation
- Genetic factors in colorectal cancer
- Radiomics and Machine Learning in Medical Imaging
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Preterm Birth and Chorioamnionitis
- Bladder and Urothelial Cancer Treatments
- Dialysis and Renal Disease Management
- Cancer Diagnosis and Treatment
- Ectopic Pregnancy Diagnosis and Management
- Reproductive tract infections research
- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Reproductive System and Pregnancy
- Erythropoietin and Anemia Treatment
- Melanoma and MAPK Pathways
- Cancer-related gene regulation
- Pelvic and Acetabular Injuries
- Acute Ischemic Stroke Management
- Cancer Treatment and Pharmacology
- Cancer, Hypoxia, and Metabolism
Yonsei University
2023-2024
Seoul National University Bundang Hospital
2011-2019
Hyeran Shim, Kiwon Jang, Yeong Hak Bang, Hoang Bao Khanh Chu, Jisun Kang, Jin-Young Lee, Sheehyun Cho, Hong Seok Jongbum Jeon, Taeyeon Hwang, Soobok Joe, Jinyeong Lim, Ji-Hye Choi, Eun Hye Joo, Kyunghee Park, Ji Hwan Moon, Kyung Yeon Han, Yourae Hong, Woo Yong Hee Cheol Kim, Seong Hyeon Yun, Beom Yoon Ah Jung Wook Huh, Kyong Shin, Dae Pyo, Hyekyung Hae-Ock Woong-Yang Jin Ok Yang & Young-Joon Kim. BMB Reports -0001;0:. https://doi.org/10.5483/BMBRep.2023-0093
Sejoon Lee, Kil-yong Ji-Hwan Park, Duck-Woo Kim, Heung-Kwon Oh, Seong-Taek Jongbum Jeon, Dongyoon Soobok Joe, Hoang Bao Khanh Chu, Jisun Kang, Jin-Young Sheehyun Cho, Hyeran Shim, Si-Cho Hong Seok Young-Joon Jin Ok Yang, Jaeim Lee & Sung-Bum Kang. BMB Reports -0001;0:. https://doi.org/10.5483/BMBRep.2023-0103
Considering the recent increase in number of colorectal cancer (CRC) cases South Korea, we aimed to clarify molecular characteristics CRC unique Korean population. To gain insights into complexities and promote exchange critical data, RNA-sequencing analysis was performed reveal mechanisms that drive development progression CRC; this is for developing effective treatment strategies. We adjacent normal tissue samples from 214 participants (comprising a total 381 including 169 212 tumor...
Soobok Joe, Jinyong Kim, Jin-Young Lee, Jongbum Jeon, Iksu Byeon, Sae-Won Han, Seung-Bum Ryoo, Kyu Joo Park, Sang-Hyun Song, Sheehyun Cho, Hyeran Shim, Hoang Bao Khanh Chu, Jisun Kang, Hong Seok DongWoo Young-Joon Tae-You Kim & Seon-Young Kim. BMB Reports -0001;0:. https://doi.org/10.5483/BMBRep.2023-0096
Aberrant DNA methylation plays a pivotal role in the onset and progression of colorectal cancer (CRC), disease with high incidence mortality rates Korea.Several CRCassociated diagnostic prognostic markers have been identified; however, due to lack comprehensive clinical methylome data, these not validated Korean population.Therefore, this study, we aimed obtain CRC profile using 172 tumors 128 adjacent normal colon tissues patients CRC.Based on comparative analysis, found that...
Mutations of the KRAS and BRAF are most frequent genetic alterations in colorectal cancer (CRC) lead to activation mitogen-activated protein kinase (MAPK) signaling pathway. CRC patients harboring or mutations have poor prognoses show limited therapeutic effects drugs targeting those mutations. PHI-501 is a potent highly selective dual inhibitor for pan-RAF DDRs. In this study, we investigated anti-tumor effect as monotherapy addressed molecular mechanism underlying overcoming resistance....
To estimate the relationship between a short mid-trimester cervical length and maternal demographics, previous obstetric history prior excisional procedures. This is single centre retrospective cohort study of 4157 consecutive women with singleton pregnancy who underwent routine assessment 20 24 weeks gestation. Data on age, weight, height, parity, (at least one spontaneous preterm birth, at term birth no termination) procedures were collected from July 2004 to April 2014. analysed cutoff...
To determine whether vitamin D binding protein (VDBP), interleukin (IL)-6 and IL-8 levels in the cervicovaginal fluid (CVF), alone or combination with clinical risk factors, can predict spontaneous preterm delivery (SPTD) women cervical insufficiency a short cervix (≤25 mm). This retrospective cohort study included 62 asymptomatic (n = 27) an 35) at 18–27 weeks. Cervicovaginal swab samples were taken for assays of VDBP, IL-6, before examination, maternal blood was collected determination...