A5091670809- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Minimally Invasive Surgical Techniques
- Gastrointestinal Tumor Research and Treatment
- Anorectal Disease Treatments and Outcomes
- Hearing, Cochlea, Tinnitus, Genetics
- Surgical Simulation and Training
- Vestibular and auditory disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Genomics and Diagnostics
- Ear Surgery and Otitis Media
- Esophageal and GI Pathology
- Facial Nerve Paralysis Treatment and Research
- Cardiac, Anesthesia and Surgical Outcomes
- Hearing Loss and Rehabilitation
- Diverticular Disease and Complications
- Stoma care and complications
- Pancreatic and Hepatic Oncology Research
- Nutrition and Health in Aging
- Noise Effects and Management
- Head and Neck Surgical Oncology
Samsung Medical Center
2015-2024
Sungkyunkwan University
2015-2024
Yonsei University
2005-2019
National Research Foundation of Korea
2016
CHA Gangnam Medical Center
2016
CHA University
2016
Christie's
2016
Creative Commons
2016
DuPage Health Coalition
2016
Yonsei University Health System
2007-2011
Mucinous adenocarcinoma (MAC) is a histological subtype of colorectal cancer. The oncologic behavior MAC differs from nonmucinous (non-MAC). Our aim in this study was to characterize patients with through evaluation large, institutional-based cohort long-term follow-up. A total 6475 stages I III cancer who underwent radical surgery were enrolled January 2000 December 2010. Prognostic comparison between (n = 274, 4.2%) and non-MAC performed. median follow-up period 48.0 months. Patients...
Anastomotic leakage (AL) is one of the most serious complications colorectal surgery. It can affect long-term oncologic outcomes, but impact on survival remains uncertain. The aim this study to evaluate operative characteristics and no groups analyze outcomes. We prospectively enrolled 10,477 patients from 2000 2011 retrospectively reviewed data. Male sex (odds ratio [OR], 3.90; P < 0.001), intraoperative transfusion (OR, 2.31; = 0.042), time 1.73; 0.032) were independent risk factors AL in...
Abstract Tumor genetic heterogeneity may underlie poor clinical outcomes because diverse subclones could be comprised of metastatic and drug resistant cells. Targeted deep sequencing has been used widely as a diagnostic tool to identify actionable mutations in cancer patients. In this study, we evaluated the utility estimating tumor using targeted panel data. We investigated prognostic impact (TH) index on outcomes, mutational profiles from data acquired 1,352 patients across 8 types. The TH...
The prognostic role of surgical resection primary tumors is not well established in patients with asymptomatic unresectable stage IV colorectal cancer.The aims this study were to reveal the and define factors affecting long-term oncological outcomes synchronous metastases.This was a retrospective analysis prospectively collected data.Between 2000 2008, total 416 cancer analyzed propensity score matching.Prematching baseline characteristics compared by bivariate analysis, 113 pairs selected...
There is ongoing debate about the appropriate criterion for defining a positive circumferential resection margin after radical surgery rectal cancer.The purpose of this work was to determine importance extent with regard outcomes in patients cancer who underwent total mesorectal excision and without neoadjuvant chemoradiotherapy.This retrospective review prospectively collected data.The study conducted tertiary care hospital.We reviewed medical charts 780 from 2004 2009. were 599 (76.8%) did...
// Bo Young Oh 1,* , Woo Yong Lee 1,2,* Sungwon Jung 3 Hye Kyung Hong 1 Do-Hyun Nam 2,4 Yoon Ah Park Wook Huh Seong Hyeon Yun Hee Cheol Kim Ho-Kyung Chun 5 and Beom Cho 1,2,6 Department of Surgery, Samsung Medical Center, Sungkyunkwan University School Medicine, Seoul, Korea 2 Health Sciences Technology, SAIHST, University, Genome Medicine Science, Graduate Gachon Incheon, 4 Neurosurgery, Kangbuk Hospital, 6 Device Management Research, * These authors have contributed equally to this work...
Objective: The aim of this study is to document perioperative results and mid-term oncologic outcomes single-incision laparoscopic (SIL) colectomy compared conventional (CL) colectomy. Background: SIL surgery an advance in minimally invasive operative techniques widely accepted for various types surgery. Methods: We prospectively collected data from 767 patients who underwent radical (250 517 CL colectomy) between 2010 2011 due primary colon cancer retrospectively analyzed these with...
The introduction of complete mesocolic excision (CME) with central vessel ligation (CVL) for right-sided colon cancer has improved oncologic outcomes. However, there is controversy over the safety laparoscopic CME CVL. This study compared short-term and long-term outcomes between open modified (mCME) CVL in patients cancer.We enrolled 1239 who underwent mCME 1010 treated by a approach right-side 2000 2013 used 1:1 propensity score matching to adjust potential baseline confounders two...
Abstract Patients with pathologic complete response (pCR) achievement can consider local excision or “watch and wait” strategy instead of a radical surgery. This study analyzed the predictive factors pCR in rectal cancer patients who underwent operation after neoadjuvant chemoradiotherapy (nCRT). also recurrence patterns achieved oncologic outcomes prognostic by ypStage. Between 2000 2013, 1,089 consecutive resection nCRT were analyzed. These classified into two groups according to pCR. The...
Local recurrence of rectal cancer is difficult to treat, may cause severe and disabling symptoms, usually has a fatal outcome. The aim this study was document the clinical nature locally recurrent determine effect surgical resection on long-term survival. A retrospective review conducted prospectively collected medical records 2485 patients with primary adenocarcinoma who underwent radical between September 1994 December 2008. In total, 147 (5.9%) exhibited local recurrence. most common type...
Multidimensional comparison between open, laparoscopy, and robotic surgery in the management of right-sided colon cancer are lacking. The aim this study was to compare early perioperative results oncologic outcomes among 3 different methods.Between June 2007 2011, a total 96 patients who underwent right hemicolectomy single institution were classified into open (OS; n=33), laparoscopy (LS; n=43), robot (RS; n=20) groups. Perioperative compared groups.Patient demographics comparable....
KRAS mutations are common in colorectal cancer (CRC). The role of mutation status as a prognostic factor remains controversial, and most large population-based cohorts usually consist patients with non-metastatic CRC. We evaluated the impact on time to recurrence (TTR) overall survival (OS) metastatic CRC who underwent curative surgery perioperative chemotherapy.Patients resection for primary synchronous metastases were retrospectively collected single institution during 6 year period...
The aim of this study was to evaluate the relationship anastomotic leakage, local recurrence, and overall survival in rectal cancer patients treated with preoperative chemoradiotherapy (CRT) curative resection.Little is known about association between leakage oncologic outcomes after CRT.A total 698 consecutive primary CRT April 19, 2000, December 27, 2013, were retrospectively reviewed. Forty-seven who had compared 651 no leakage.Of patients, 47 (6.7%) leakage. Among these 39 (83.0%) grade...
// Jeeyun Lee 1, * , Hee Cheol Kim 2, Jung Yong Hong 3, Kai Wang 4 Sun Young 1 Jiryeon Jang Seung Tae Joon Oh Park Ho Yeong Lim Won Ki Kang Suk Jiyun Woo 2 Yoon Ah Wook Huh Seong Hyeon Yun In-Gu Do 5 Seok Hyung Sohail Balasubramanian Philip J. Stephens Jeffrey S. Ross 4, 6 Gang Gary Li 7 Zachary Hornby Siraj M. Ali Vincent A. Miller Kyoung-Mee 5, 8 Sai-Hong Ignatius Ou 9 Department of Medicine, Division Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School Seoul,...
The aim of this study is to evaluate the prognosis for patients with a signet-ring-cell carcinoma (SRCC) who undergo curative surgery by comparing them an adenocarcinoma (ADC), excluding mucinous ADC.Between September 1994 and December 2013, 14,110 colorectal cancer underwent among them, 12,631 were enrolled in study. 71 SRCC 12,570 ADC identified. We analyzed disease-free survival overall rates before after 1:2 propensity score matching evaluated those stage stratification.The median...
BACKGROUND: The type of surgery performed for primary transverse colon cancer varies based on tumor characteristics and surgeon perspective. optimal oncological outcome following different surgical options has not been clearly established, colectomy shown equivalence only in small cohort studies. OBJECTIVE: Our aim was to compare long-term outcomes after versus extended resection cancer. DESIGN: This study is a retrospective review prospectively collected data. SETTING: conducted at tertiary...