A5092564130- Cellular Mechanics and Interactions
- Neurofibromatosis and Schwannoma Cases
- Signaling Pathways in Disease
- Bone Metabolism and Diseases
- Cell Adhesion Molecules Research
- Microtubule and mitosis dynamics
- S100 Proteins and Annexins
- Galectins and Cancer Biology
- Hippo pathway signaling and YAP/TAZ
- Phagocytosis and Immune Regulation
Institut de Pharmacologie et de Biologie Structurale
2023-2024
Université Toulouse III - Paul Sabatier
2023-2024
Université de Toulouse
2023-2024
Centre National de la Recherche Scientifique
2023-2024
Institute for Research in Immunology and Cancer
2023-2024
Université de Montréal
2023-2024
Cell-cell fusion is an evolutionarily conserved process that essential for many functions, including fertilisation and the formation of placenta, muscle osteoclasts, multinucleated cells are unique in their ability to resorb bone. The mechanisms osteoclast multinucleation involve dynamic interactions between actin cytoskeleton plasma membrane still poorly characterized. Here, we found moesin, a cytoskeletal linker protein member Ezrin/Radixin/Moesin (ERM) family, activated during maturation...
Abstract The cellular actin cortex provides crucial mechanical support and plays critical roles in numerous functions, including cell division migration. proteins of the ERM family, ezrin, radixin, moesin, are central to these processes by linking plasma membrane cytoskeleton. To investigate individual contributions three leukocyte migration, we generated single triple knock-out macrophages. Surprisingly, found that even absence ERMs, macrophages can still form different structures promoting...
Abstract The cellular cortex provides crucial mechanical support and plays critical roles during cell division migration. proteins of the ERM family, comprised ezrin, radixin, moesin, are central to these processes by linking plasma membrane actin cytoskeleton. To investigate contributions leukocyte migration, we generated single triple knockout macrophages. Surprisingly, found that even in absence proteins, macrophages still form different structures promoting such as filopodia,...