Jianhua Liang

ORCID: 0009-0002-8070-9222
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About
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Research Areas
  • Spectroscopy and Chemometric Analyses
  • Tea Polyphenols and Effects
  • Advanced Chemical Sensor Technologies
  • melanin and skin pigmentation
  • Eosinophilic Disorders and Syndromes
  • interferon and immune responses
  • Drug-Induced Adverse Reactions
  • RNA regulation and disease
  • Immune Cell Function and Interaction
  • Immunodeficiency and Autoimmune Disorders
  • Phytochemicals and Antioxidant Activities
  • Peripheral Neuropathies and Disorders
  • Pharmacological Effects of Natural Compounds
  • Cancer, Hypoxia, and Metabolism
  • Autoimmune Neurological Disorders and Treatments
  • Urticaria and Related Conditions
  • Lymphoma Diagnosis and Treatment
  • Chemokine receptors and signaling
  • Ferroptosis and cancer prognosis
  • Immunotherapy and Immune Responses
  • Cancer Cells and Metastasis
  • Genomics, phytochemicals, and oxidative stress
  • Meat and Animal Product Quality
  • Epigenetics and DNA Methylation
  • Chronic Lymphocytic Leukemia Research

Tea Research Institute
2023-2024

South China Agricultural University
2023-2024

Guangdong Academy of Agricultural Sciences
2023

Taishan Medical University
2020

Kunming University of Science and Technology
2020

Liaocheng People's Hospital
2014-2020

Peking University First Hospital
2018

Peking University
2018

Nanjing Medical University
2016

Jiangsu Province Hospital
2016

Abstract Vitiligo is a common depigmentary skin disease that may follow pattern of multifactorial inheritance. The essential factors its immunopathogenesis thought to be the selective destruction melanocytes. As new class microregulators gene expression, mi RNA have been reported play vital roles in autoimmune diseases, metabolic diseases and cancer. This study sought characterize different expression peripheral blood mononuclear cells ( PBMC ) patients with non‐segmental vitiligo NSV...

10.1111/1346-8138.12725 article EN The Journal of Dermatology 2014-12-12

Dancong tea is famous for floral aroma and strong, sweet aftertaste. Dry-heating post-treatment (DHP treatment) used to decrease astringency bitterness in oolong teas, but the effects of it on taste profiles teas are unknown. Here, sensory biochemical characteristics two differently-scented varieties (YS LH) were assessed both before after DHP treatment. Overall, treatment improved infusions. The concentrations theasinensins theaflavins, which contribute infusion colour taste, varied...

10.1016/j.lwt.2023.115118 article EN cc-by-nc-nd LWT 2023-07-27

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a hypersensitivity characterized by maculopapular rash, exfoliative dermatitis, lymphadenopathy, fever, eosinophilia, involvement of internal organs. Evidence for reactivation herpes family viruses has been observed in some DRESS patients, activated CD8+ T lymphocytes are largely directed against Epstein-Barr virus. Here, we report two cases complicated this infection. Both patients received antibiotics non-steroidal...

10.5021/ad.2018.30.1.71 article EN Annals of Dermatology 2018-01-01

Angiogenesis and the tumor microenvironment (TME) play important roles in tumorigenesis. Forkhead box Q1 (FOXQ1) is a well-established oncogene multiple tumors, including colorectal cancer (CRC); however, whether FOXQ1 contributes to angiogenesis TME modification CRC remains largely uncharacterized. Here, we demonstrate an essential role of FOXQ1-induced macrophage recruitment that related its ability promote migration endothelial cells macrophages through activation EGF/PDGF pathway...

10.3389/fonc.2020.564298 article EN cc-by Frontiers in Oncology 2020-11-30

Cytokine-induced killer (CIK) cells are a group of heterogeneous immune which can be isolated from human peripheral blood mononuclear and have demonstrated therapeutic benefit both in hematologic malignancies solid tumors, including colorectal cancer. However, poor tumor‑targeted migration has limited the clinical efficacy CIK cell treatment. The chemokine‑chemokine receptor (CK‑CKR) axis serves role tumor‑directed trafficking capacity cells. Investigating relationship between CKR profiles...

10.3892/ol.2020.11539 article EN Oncology Letters 2020-04-15

Vitiligo is a disorder caused by the loss of melanocyte activity on melanin pigment generation. Studies show that oxidative-stress induced apoptosis in melanocytes closely related to pathogenesis vitiligo. Glutamine well known antioxidant with anti-apoptotic effects, and used variety diseases. However, it unclear whether glutamine has an or effect melanocytes.The aim this study was investigate protective effects human oxidative stress model.The model established using hydrogen peroxide. The...

10.4103/ijdvl.ijdvl_106_17 article EN Indian Journal of Dermatology Venereology and Leprology 2018-01-01

Expression of ζ-chain-associated protein kinase 70 kDa (ZAP-70) in chronic lymphocytic leukemia (CLL) is associated with more aggressive disease and can help differentiate CLL from cases expressing mutated or unmutated immunoglobulin heavy chain variable region (IgHV) genes. However, standardizing ZAP-70 expression by flow cytometric analysis has proved unsatisfactory. The key point that weakly expressed a continuous pattern rather than clear discrimination between positive negative cells,...

10.2147/ott.s94613 article EN cc-by-nc OncoTargets and Therapy 2016-02-01

Anti-leucine-rich glioma inactivated-1 (anti-LGI1) encephalitis is a subgroup of autoimmune encephalitis. We herein report the case 60-year-old man who presented with typical symptoms, including short-term memory loss, mental abnormalities, hyponatremia and seizures characterized by faciobrachial dystonic was diagnosed anti-LGI1 At same time, he essential thrombocythemia. A significant improvement obtained treatment corticosteroid, immunoglobulin, mycophenolate mofetil, hydroxyurea....

10.2169/internalmedicine.2963-19 article EN Internal Medicine 2020-01-14
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