A5100454343- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Immunodeficiency and Autoimmune Disorders
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Nail Diseases and Treatments
- Plant Pathogens and Fungal Diseases
- CO2 Reduction Techniques and Catalysts
- Chemical synthesis and alkaloids
- Meningioma and schwannoma management
- Ionic liquids properties and applications
- Electron Spin Resonance Studies
- Electrocatalysts for Energy Conversion
- Colorectal Cancer Surgical Treatments
- Infectious Diseases and Mycology
- Chronic Lymphocytic Leukemia Research
- Blood disorders and treatments
- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- Tumors and Oncological Cases
- Anorectal Disease Treatments and Outcomes
- Cancer Cells and Metastasis
- Renal Diseases and Glomerulopathies
- Immune Response and Inflammation
- Mycobacterium research and diagnosis
- Antioxidant Activity and Oxidative Stress
Peking University First Hospital
2016-2025
Peking University
2016-2025
National Clinical Research Center for Digestive Diseases
2021-2025
Hefei National Center for Physical Sciences at Nanoscale
2022-2024
University of Science and Technology of China
2022-2024
Jiangxi Provincial People's Hospital
2024
Wuhan Children's Hospital
2023
Huazhong University of Science and Technology
2023
Tianjin University of Traditional Chinese Medicine
2023
National Clinical Research
2023
Abstract The carbon−carbon coupling at the Cu/Cu 2 O Schottky interface has been widely recognized as a promising approach for electrocatalytic CO conversion into value-added alcohols. However, limited selectivity of C 2+ alcohols persists due to insufficient control over rectifying characteristics required precise bonding oxyhydrocarbons. Herein, we present an investigation manipulation coordination environment Cu sites through in-situ electrochemical reconstruction strategy, which...
Abstract Bismuth‐based electrocatalysts are promising candidates for electrochemical CO 2 reduction to formate attributing the accelerated formation of *OCHO intermediate, while high‐energy consumption remains a major challenge practicability. Herein, we present ultrathin Bi O 3 nanosheets with abundant oxygen vacancy ( Vo ‐BOC‐NS) reconstructed from S, N‐co‐doped bismuth oxides that can act as durable electrocatalyst ‐to‐formate conversion faradic efficiency (FE ) >95%, partial current...
Abstract Background Lycorine hydrochloride (LH), an alkaloid extracted from the bulb of Lycoris radiata , is considered to have anti-viral, anti-malarial, and anti-tumorous effects. At present, underlying mechanisms LH in gastric cancer remain unclear. MCL1, anti-apoptotic protein BCL2 family, closely related drug resistance tumor. Therefore, MCL1 as a potential target for treatment. Methods The effect on was assessed vitro (by MTT, BrdU, western blotting…) vivo immunohistochemistry)....
Heterozygous STAT1 gain-of-function (GOF) mutations are associated with chronic mucocutaneous candidiasis and a broad spectrum of infectious, inflammatory, vascular manifestations. We describe therapeutic failures the Janus Kinase (JAK) inhibitor ruxolitinib in 2 GOF patients severe invasive or cutaneous fungal infections.
Abstract Bismuth‐based materials have emerged as promising catalysts in the electrocatalytic reduction of CO 2 to formate. However, reasons for reconstruction Bi‐based precursors form bismuth nanosheets are still puzzling, especially formation defective sites. Herein, we prepare with vacancy‐rich defects (V‐Bi NS) by rapidly reconstructing Bi 19 Cl 3 S 27 under negative potential. Theoretical analysis reveals that introduction chlorine induces generation intrinsic electric field precursor,...
Vulvovaginal candidiasis (VVC) is an inflammation caused by Candida albicans with a higher recurrence rate in individuals deficient Card9. This study aimed to elucidate the mechanisms underlying this increased susceptibility. Estrogen-treated Card9-/- mice infected C. were used model Card9 deficiency-related VVC. Our findings indicate that deficiency leads reduction Th17 cells, interleukin (IL)-17-producing γδ T and IL-17A secretion, weakens epithelial tight junctions, reduces antimicrobial...
This study aims to conduct an in-depth analysis of diabetic foot ulcer (DFU) images using deep learning models, achieving automated segmentation and classification the wounds, with goal exploring application artificial intelligence in field care. A total 671 DFU were selected for manual annotation periwound erythema, boundaries, various components within wounds (granulation tissue, necrotic tendons, bone gangrene). Three instance models (Mask2former, Deeplabv3plus, Swin-Transformer)...
Bismuth-based materials have emerged as promising catalysts in the electrocatalytic reduction of CO
Abstract Aim This study aimed to analyse the potential significance of metastasis inferior mesenteric artery lymph node (IMA‐LN) in patients with malignancy left colon and rectum. Method A retrospective analysis a cohort 890 collected prospectively who underwent radical resection primary tumour descending colon, sigmoid rectum our department from 1 January 2009 31 December 2015 was performed. Patients were divided into an IMA‐LN ( IMA ‐ LN (+)) group n = 51) non (IMA‐LN (‐)) 839). total 801...
Abstract Aim Denonvilliers’ fascia is thought to be a multilayered fascial structure, based on its embryological development with the neurovascular bundle embedded within it. Recently, this theory had been proven histologically and by confocal microscopy in many published articles. However, literature does not report how surgeons can identify these structures. We aimed determine optimal surgical approach for preserving critical Method Eighteen cadavers (13 male/five female) were included...
The foodborne pathogen Listeria monocytogenes employs a number of virulence determinants including metalloproteases to infect hosts. Here for the first time, we identified an M29 family aminopeptidase T (encoded by lmo1603) from L. that possesses typical feature catalyze cleavage amino acids peptide substrates, with preference arginine. purified recombinant Lmo1603 was activated Fe(3+), Zn(2+) and Mn(2+), but strongly stimulated Co(2+), indicating is cobalt-dependent aminopeptidase. Single...
Invasive aspergillosis mainly occurs in immunocompromised patients and is commonly caused by <i>Aspergillus fumigatus</i>, while <i>A.</i><i>nidulans</i> rarely the causative agent. However, chronic granulomatous disease (CGD) patients, <i>A. nidulans</i> a frequent cause of invasive associated with higher mortality. Immune recognition nidulans </i>was compared to fumigatus </i>to offer an insight into why infections are prevalent...