A5063906935- Colorectal Cancer Surgical Treatments
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Screening and Detection
- Cardiac, Anesthesia and Surgical Outcomes
- Diverticular Disease and Complications
- Colorectal and Anal Carcinomas
- Appendicitis Diagnosis and Management
- Genetic factors in colorectal cancer
- Bariatric Surgery and Outcomes
- Gastroesophageal reflux and treatments
- Stoma care and complications
- Esophageal Cancer Research and Treatment
- Ferroptosis and cancer prognosis
- Colorectal Cancer Treatments and Studies
- Enhanced Recovery After Surgery
- Hernia repair and management
- Pediatric Hepatobiliary Diseases and Treatments
- Ovarian function and disorders
- Diagnosis and treatment of tuberculosis
- COVID-19 and healthcare impacts
- Intraperitoneal and Appendiceal Malignancies
- RNA Research and Splicing
- Cancer, Lipids, and Metabolism
- Myofascial pain diagnosis and treatment
- Cancer Mechanisms and Therapy
Suez Canal University
2018-2024
Fujian Medical University
2018-2022
Sahlgrenska University Hospital
2022
Helsingborgs lasarett
2022
Alexandria University
2022
Mansoura University
2022
Union Hospital
2018-2022
Prediction of the onset de novo gastroesophageal reflux disease (GERD) after sleeve gastrectomy (SG) would be helpful in decision-making and selection optimal bariatric procedure for every patient. The present study aimed to develop an artificial intelligence (AI)-based model predict GERD SG help clinicians surgeons decision-making.A prospectively maintained database patients with severe obesity who underwent was used development AI using all available data points. dataset arbitrarily split...
Abstract The resistance against oxaliplatin (L‐OHP) based regimens remains a major obstacle for its efficient usage in treating metastatic colorectal cancer (mCRC). In this study, we performed weighted gene coexpression network analysis (WGCNA) to systematically screen the relevant hub genes L‐OHP using raw microarray data of 30 consecutive mCRC samples from our earlier study (GSE69657). results were further confirmed through datasets Gene Expression Omnibus (GEO). From module, nine both and...
SPINK4 is known as a gastrointestinal peptide in the tract and abundantly expressed human goblet cells. The clinical significance of colorectal cancer (CRC) largely unknown.We retrieved expression data 1168 CRC patients from 3 Gene Expression Omnibus (GEO) datasets (GSE24551, GSE39582, GSE32323) Cancer Genome Atlas (TCGA) to compare level between tissues normal evaluate its value predicting survival patients. At protein level, these results were further confirmed by mining Human Protein...
Abstract Purpose The enhanced recovery after surgery (ERAS) program expedites patient major surgery. This study aimed to investigate the role of triad procalcitonin (PCT), C-reactive protein (CRP), and white blood cells (WBC) trajectories as a predictive biomarker for anastomotic leak (AL) colorectal Method Patients who had anastomosis were prospectively included. Postoperative clinical laboratory parameters outcomes collected analyzed. 5-day PCT, CRP, WBC evaluated. Based on trajectory...
To provide systematic insight into the composition and expression of transfer RNA (tRNA) derivatives transcriptome in colorectal cancer (CRC). tRNA profiles three pairs CRC adjacent normal colon tissues were performed by tRNA-derived small fragments (tRFs) halves (tiRNA) sequencing, microarray data transcriptomes from paired controls retrieved Gene Expression Omnibus database. The differentially expressed tRFs tiRNAs genes between samples screened. functional regulations tRF tiRNA gene...
Abstract Aim Denonvilliers’ fascia is thought to be a multilayered fascial structure, based on its embryological development with the neurovascular bundle embedded within it. Recently, this theory had been proven histologically and by confocal microscopy in many published articles. However, literature does not report how surgeons can identify these structures. We aimed determine optimal surgical approach for preserving critical Method Eighteen cadavers (13 male/five female) were included...
Abstract Neoadjuvant chemoradiotherapy (CRT) resistance is a complex phenomenon and it remains major problem for patients with priori resistant tumor. Therefore, there strong need to investigate molecular biomarkers which may guide treatment decision‐making. In our study, weighted gene coexpression network analysis was applied identify CRT‐resistance hub modules in 12 colorectal cancer (CRC) cell lines different CRT sensitivities from GSE20298 data set. The green module purple had the...
Although obesity is a popular reason for choosing laparoscopic appendectomy (LA) versus open (OA), however, the question of whether there difference remains. Our goal to investigate if between OA and LA in obese patients.Fifty-eight patients diagnosed with acute appendicitis according ALVARDO score at department surgery Suez Canal university hospitals from March 2020 till August 2021 were included. The study participants assigned two groups OA. This aimed comparing regarding intraoperative...
Abstract Background The relative anatomical understanding of the perirectal fasciae is paramount importance for proper performance total mesorectal excision (TME). This study was to demonstrate planes TME and validates intraoperative findings using cadaveric observations. Methods In this combined retrospective prospective study, bilateral attachment rectosacral fascia (RSF) observed in 28 specimens (male, n = 14; female, 14). From January 2018 December 2019, surgical videos 67 patients who...
Background: As Clomiphene citrate (CC) is widely used in treatment of infertility polycystic ovarian syndrome (PCOS). Aim: To evaluate rate ovulation using CC "stair step protocol" compared to "traditional protocol". Methods: A randomized clinical trial conducted on 60 infertile PCO were randomly divided 2 groups, group (A) "Stair Step which was administrated day 6 menses then transvaginal ultrasound (TVUS) done, if follicular diameter less than 18 mm 14 increasing dose 100 mg days for...
Background: Roux-en-Y hepaticojejunostomy (RYHJ) is currently considered the definitive treatment for iatrogenic bileduct injuries. This work aimed to assess medical indications HJ and analyze postoperative complications of HJ.Patients Methods: prospective observational was conducted on 33 patients who underwent variousbenign diseases. The were divided into two groups: Patients with (n=19) no complicationsgroup (n=14).Results: had a longer mean hospital stay higher average blood loss...
Objective: To observe the anatomical architecture of rectosacral fascia and discuss best plan for accurate peri-rectal dissection in laparoscopic/robotic total mesorectal resection (TME). Methods: A descriptive cohort study was carried out. 127 patients with rectal cancer who underwent TME Department Colorectal Surgery at affiliated Union hospital Fujian Medical University were included, patients' demographics their pathological details operation videos collected analysis. Another 20...
Although the clinical importance of complete, intact total mesorectal excision (TME) is widely accepted standard for decreasing local recurrence rectal cancer, residual mesorectum still represents a significant component resection margin involvement. This study aimed to use visible intraoperative sign detect distal end ensure complete inclusion and avoid unnecessary over-dissection. The was investigated retrospectively through review 124 operative videos at Union Hospital Fujian Medical...