A5100351287- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Treatments and Studies
- Nutrition and Health in Aging
- Ferroptosis and cancer prognosis
- Radiomics and Machine Learning in Medical Imaging
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Frailty in Older Adults
- Cancer-related molecular mechanisms research
- Intraperitoneal and Appendiceal Malignancies
- Anorectal Disease Treatments and Outcomes
- Body Composition Measurement Techniques
- Cancer, Lipids, and Metabolism
- Lung Cancer Treatments and Mutations
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Inflammatory Biomarkers in Disease Prognosis
- Lung Cancer Research Studies
- Ovarian cancer diagnosis and treatment
- Cancer Genomics and Diagnostics
- Angiogenesis and VEGF in Cancer
- Stoma care and complications
- RNA modifications and cancer
Fujian Medical University
2016-2025
Union Hospital
2016-2025
Fujian Provincial Cancer Hospital
2009-2025
First Affiliated Hospital of Fujian Medical University
2023-2024
Fujian Electric Power Survey & Design Institute
2024
Second Affiliated Hospital of Zhejiang University
2022-2024
Zhejiang University
2024
Union Hospital
2020-2023
Guangzhou Development Zone Hospital
2022-2023
Army Medical University
2022
Abstract Early and accurate diagnosis of focal liver lesions is crucial for effective treatment prognosis. We developed validated a fully automated diagnostic system named Liver Artificial Intelligence Diagnosis System (LiAIDS) based on diverse sample 12,610 patients from 18 hospitals, both retrospectively prospectively. In this study, LiAIDS achieved an F1-score 0.940 benign 0.692 malignant lesions, outperforming junior radiologists (benign: 0.830-0.890, malignant: 0.230-0.360) being par...
AIM:To compare the prevalence of Functional gas trointestinal disorders (FGIDs) using ROME Ⅲ and Ⅱ to describe predictors FGIDs among eating disorder (ED) patients. METHODS:Two similar cohorts female ED inpatients, aged 1750 years, with no organic gastrointestinal or systemic disorders, completed either (n = 100) 160) questionnaire on admission for treatment.The two were compared continuous demographic variables (e.g. , age, BMI) Student's t tests, categorical diagnosis) χ 2 tests.The...
Abstract The resistance against oxaliplatin (L‐OHP) based regimens remains a major obstacle for its efficient usage in treating metastatic colorectal cancer (mCRC). In this study, we performed weighted gene coexpression network analysis (WGCNA) to systematically screen the relevant hub genes L‐OHP using raw microarray data of 30 consecutive mCRC samples from our earlier study (GSE69657). results were further confirmed through datasets Gene Expression Omnibus (GEO). From module, nine both and...
SPINK4 is known as a gastrointestinal peptide in the tract and abundantly expressed human goblet cells. The clinical significance of colorectal cancer (CRC) largely unknown.We retrieved expression data 1168 CRC patients from 3 Gene Expression Omnibus (GEO) datasets (GSE24551, GSE39582, GSE32323) Cancer Genome Atlas (TCGA) to compare level between tissues normal evaluate its value predicting survival patients. At protein level, these results were further confirmed by mining Human Protein...
BACKGROUND Human immunodeficiency virus (HIV)–positive men who have sex with (MSM) are at disproportionately high risk for anal cancer. There is no definitive approach to the management of high‐grade squamous intraepithelial lesions (HSIL), which precursors cancer, and evidence suggests that posttreatment adjuvant quadrivalent human papillomavirus (qHPV) vaccination improves HSIL treatment effectiveness. The objectives this study were evaluate optimal strategy respect clinical effectiveness...
To provide systematic insight into the composition and expression of transfer RNA (tRNA) derivatives transcriptome in colorectal cancer (CRC). tRNA profiles three pairs CRC adjacent normal colon tissues were performed by tRNA-derived small fragments (tRFs) halves (tiRNA) sequencing, microarray data transcriptomes from paired controls retrieved Gene Expression Omnibus database. The differentially expressed tRFs tiRNAs genes between samples screened. functional regulations tRF tiRNA gene...
To investigate the clinicopathological and prognostic factors related to early gastric cancer recurrence after curative resection.Between October 2006 August 2018, a total of 149 patients with cancer/adenocarcinoma esophagogastric junction resection were enrolled from our treatment group. A retrospective clinical analysis was performed on these resection.Among patients, 99 (66.4%) had only one pattern, 50 (33.6%) multiple patterns. The median recurrence-free survival (RFS) 18.2 months (95%...
Conditional survival (CS) takes into consideration the duration of post-surgery and can provide valuable additional insights. The aim this study was to investigate risk factors associated with reduced one-year postoperative conditional in patients diagnosed stage III T3-T4 colon cancer real-time prognosis prediction. Furthermore, we develop pertinent nomograms predictive models.
Abstract Neoadjuvant chemoradiotherapy (CRT) resistance is a complex phenomenon and it remains major problem for patients with priori resistant tumor. Therefore, there strong need to investigate molecular biomarkers which may guide treatment decision‐making. In our study, weighted gene coexpression network analysis was applied identify CRT‐resistance hub modules in 12 colorectal cancer (CRC) cell lines different CRT sensitivities from GSE20298 data set. The green module purple had the...
Neuroligin1 (NLGN1) is a main component of excitatory glutamatergic synapses complex and important for synapse assembly function. The clinical value NLGN1 in colorectal cancer (CRC) not clear.We obtained the expression data 1143 CRC patients from 3 independent Gene Expression Omnibus (GEO) datasets (GSE32323, GSE24551, GSE39582) Cancer Genome Atlas (TCGA) to make comparison level between tissues matched noncancerous tissues, evaluate its predicting survival patients. At protein level, these...