A5111684661- Photoacoustic and Ultrasonic Imaging
- Optical Imaging and Spectroscopy Techniques
- Spectroscopy Techniques in Biomedical and Chemical Research
- Advanced Vision and Imaging
- Topic Modeling
- Optical measurement and interference techniques
- Birth, Development, and Health
- Data Quality and Management
- bioluminescence and chemiluminescence research
- Advanced Graph Neural Networks
- Pregnancy and preeclampsia studies
- Advanced Fluorescence Microscopy Techniques
- Advanced Text Analysis Techniques
- Image Enhancement Techniques
- Infrared Thermography in Medicine
- Cell Image Analysis Techniques
- Microwave Imaging and Scattering Analysis
- Ultrasound Imaging and Elastography
- Computer Graphics and Visualization Techniques
- 3D Surveying and Cultural Heritage
- Calibration and Measurement Techniques
- Software Engineering Techniques and Practices
- Medical Imaging Techniques and Applications
- Image Processing Techniques and Applications
- Photodynamic Therapy Research Studies
Chinese Academy of Sciences
2008-2023
Kunming Institute of Zoology
2023
Hefei University of Technology
2022
Shandong Institute of Automation
2011-2013
Institute of Automation
2010-2011
University of Kentucky
2010
Ocean University of China
2007
In vivo bioluminescence imaging (BLI) has played a more and important role in biomedical research of small animals. Bioluminescence tomography (BLT) further translates the BLI optical information into three-dimensional bioluminescent source distribution, which could greatly facilitate applications related studies. Although diffusion approximation (DA) is one most widely-used forward models, higher-order approximations are still needed for animal imaging. this work, as relatively accurate...
This study proposes a precise and rapid binocular camera calibration (BCC) method based on stereo target composed of 12 coded planar targets which each corner has unique number. Unlike Zhang's requires numerous pairs images in process fails to realize the matching homonymous corners case incomplete projection, proposed can implement an accurate BCC using single image per even incompete projection. The greatly decreases complexity process. An optimization multi-constraint is also presented...
Bioluminescence imaging (BLI) makes it possible to elucidate molecular and cellular signatures better understand the effects of human disease in small animal models vivo. The unambiguous three-dimensional bioluminescent source information obtained by bioluminescence tomography (BLT) could further facilitate its applications biomedicine. However, best our knowledge, existing gradient-type reconstruction methods BLT are inefficient, often require a relatively volume interest (VOI) for feasible...
A reconstruction method is presented for spectrally resolved three-dimensional bioluminescence tomography (BLT) in heterogeneous media using a level-set strategy. In order to reconstruct internal bioluminescent sources, strategy utilized quantitatively localize the distribution of sources. The results numerical phantom experiments clearly show that proposed can tolerate different initial values and noise levels and, furthermore, work credibly even when number phases (levels) not known...
Bioluminescence tomography (BLT) is an effective molecular imaging (MI) modality. Because of the ill-posedness, inverse problem BLT still open. We present a trust region method (TRM) for source reconstruction. The TRM applied in reconstruction procedure first time. results both numerical simulations and experiments cube phantom nude mouse draw us to conclusion that based on adaptive finite element (AFE) framework, works BLT. To make our more reliable, we also compare performance famous...
Generally, the performance of tomographic bioluminescence imaging is dependent on several factors, such as regularization parameters and initial guess source distribution. In this paper, a global-inexact-Newton based reconstruction method, which regularized by dynamic sparse term, presented for reconstruction. The proposed method can enhance higher reliability efficiency. vivo mouse experimental reconstructions were performed to validate method. Reconstruction comparisons with other methods...
Bioluminescence tomography (BLT) has become a powerful tool for whole-body small animal imaging. In this contribution, an adaptive improved element free Galerkin method (IEFGM) is presented to perform quantitative reconstruction of the internal light source using quasi- or multi-spectral information, which not only can avoid time-consuming mesh generation but also reduce ill-posedness BLT effectively. algorithm, be largely enhanced by technology based on posteriori error estimation. Finally,...
Purpose: Bioluminescence tomography (BLT) provides an effective tool for monitoring physiological and pathological activities in vivo . However, the measured data bioluminescence imaging are corrupted by noise. Therefore, regularization methods commonly used to find a regularized solution. Nevertheless, quality of reconstructed bioluminescent source obtained methods, choice parameters is crucial. To date, selection remains challenging. With regards above problems, authors proposed BLT...
In molecular imaging (MI), especially the optical imaging, bioluminescence tomography (BLT) emerges as an effective modality for small animal imaging. The finite element methods (FEMs), adaptive (AFE) framework, play important role in BLT. processing speed of FEMs and AFE framework still needs to be improved, although multi-thread CPU technology multi have already been applied. this paper, we first time introduce a new kind acceleration accelerate BLT, using graphics unit (GPU). Besides...
Summary Compared with lowlander migrants, native Tibetans have a higher reproductive success at high altitude though the underlying mechanism remains unclear. Here, we compared transcriptome and histology of full-term placentas between Han migrants. We found that placental trophoblast shows largest expression divergence Han, show decreased immune response endoplasmic reticulum stress. Remarkably, detected sex-biased divergence, where male-infant greater between-population difference than...
PDF HTML阅读 XML下载 导出引用 引用提醒 Monte Carlo方法在扩散光学成像仿真中的应用 DOI: 作者: 作者单位: 作者简介: 通讯作者: 中图分类号: 基金项目: Supported by the National Natural Science Foundation of China under Grant Nos.30672690, 30600151, 90209008, 60532050, 60621001, 30873462 (国家自然科学基金); Basic Research Program No.2006CB705700 (国家重点基础研究发展计划(973)); for Cheung Kong Scholars and Innovative Team in University No.IRT0645 (长江学者和创新团队发展计划); CAS Hundred Talents (中国科学院百人计划); Scientific Equipment Develop Nos.YZ0642, YZ200766 (中国科学院科研装备研制项目); Joint...
In vivo bioluminescence imaging (BLI) has played a more and important role in biomedical research of small animals. Tomographic (TBI) further translates the BLI optical information into three-dimensional bioluminescent source distribution, which could greatly facilitate applications related studies. Although diffusion approximation (DA) is one most widely-used forward models, higher-order approximations are still needed for animal imaging. this work, as relatively accurate theory, simplified...
As an emerging and promising molecular imaging modality, bioluminescence tomography (BLT) can reconstruct the internal light source with photon fluence on small animal surface to reveal non-invasive cellular activities directly. In order obtain higher precision better spatial resolution in reconstruction, solution accuracy for forward problem of BLT should be improved as high possible. this contribution, we present a modified element free Galerkin method (MEFGM) calculate propagation...
Recent advances in optical molecular imaging technology have led to great improvements image resolution, and are increasingly being applied non-invasively delineate vivo physiological pathological processes at cellular levels. It provides the potential for understanding of integrative biology, earlier detection characterization disease evaluation treatment. This paper focuses on typical modalities as well their clinical applications future development.
Bioluminescence imaging (BLI) offers an alternative opportunity for non-invasively visualizing biological processes at the physiological and molecular levels in whole animals. Tomographic bioluminescence (TBI) can further translate planar into three-dimensional quantitative bioluminescent source distribution. Although many reconstruction methods have been developed, efforts are still needed to make tomographic more practical biomedical experiments. In this paper, a fast algorithm based on...
Bioluminescence imaging (BLI) and bioluminescence tomography (BLT) make it possible to elucidate cellular signatures better understand the effects of human disease in small animal vivo. However, best our knowledge, existing gradient-type reconstruction methods BLT are not very efficient, often require a relatively volume interest (VOI) for feasible results. In this paper, fast graph cuts based method is presented, which localize bioluminescent source heterogeneous mouse atlas via...
Underwater optical effect simulation is an important part of simulating natural scene. However, computing these effects difficult and time-consuming, since light refracts when passing through waves. To address the problem, this paper proposes a simple quick method for rendering underwater scenes, including shafts refracted by dynamic water surface, caustics caused shadows beneath creatures in water. The simplifies Iwasaki's to save computation-time eye-irrelative calculating intensities...