Yujie Lu

ORCID: 0000-0002-2468-4625
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About
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Research Areas
  • Optical Imaging and Spectroscopy Techniques
  • Photoacoustic and Ultrasonic Imaging
  • Medical Imaging Techniques and Applications
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Antimicrobial Resistance in Staphylococcus
  • Radiation Dose and Imaging
  • Advanced X-ray and CT Imaging
  • Nanoplatforms for cancer theranostics
  • bioluminescence and chemiluminescence research
  • Ocular Infections and Treatments
  • Medical Image Segmentation Techniques
  • Photodynamic Therapy Research Studies
  • Digital Holography and Microscopy
  • Advanced Fluorescence Microscopy Techniques
  • Advancements in Transdermal Drug Delivery
  • Advanced X-ray Imaging Techniques
  • Photonic and Optical Devices
  • Antifungal resistance and susceptibility
  • 3D Shape Modeling and Analysis
  • Optical measurement and interference techniques
  • Optical Coherence Tomography Applications
  • Advanced Fiber Optic Sensors
  • Retinal and Macular Surgery
  • Animal Nutrition and Physiology
  • Circular RNAs in diseases

Guangxi Medical University
2025

Jiangsu University of Science and Technology
2023-2024

Shenzhen Academy of Robotics
2023

Zhejiang Chinese Medical University
2022-2023

Donghua University
2023

Southeast University
2023

Jiangsu University
2023

Hubei University of Technology
2022

Ningbo University
2022

Guangxi University
2022

Nanoparticles are regarded as promising transfection reagents for effective and safe delivery of nucleic acids into a specific type cells or tissues providing an alternative manipulation/therapy strategy to viral gene delivery. However, the current process searching novel materials is limited due conventional low-throughput time-consuming multistep synthetic approaches. Additionally, approaches frequently accompanied with unpredictability continual optimization refinements, impeding flexible...

10.1021/nn101908e article EN ACS Nano 2010-10-06

Through restoration of the light source information in small animals vivo, optical molecular imaging, such as fluorescence tomography (FMT) and bioluminescence (BLT), can depict biological physiological changes observed using probes. A priori plays an indispensable role tomographic reconstruction. As a type information, sparsity characteristic has not been sufficiently considered to date. In this paper, we introduce compressed sensing method develop new algorithm for spectrally-resolved...

10.1364/oe.17.008062 article EN cc-by Optics Express 2009-04-29

A taper-based Mach-Zehnder interferometer (MZI) embedded in a thinned optical fiber is demonstrated as highly sensitive refractive index (RI) sensor. RI sensitivity of 2210.84 nm/RIU (refractive unit) obtained at the external 1.40, which ten times higher than that normal taper- and long-period grating (LPFG)-based sensors. The can be further improved by decreasing diameter increasing length MZI. proposed MZIs have lower temperature sensitivities compared with sensors, desirable merit for...

10.1364/ao.50.005503 article EN Applied Optics 2011-09-29

We report a microfluidic fiber-optic refractive index (RI) sensor based on an in-line Fabry-Perot (FP) interferometer, which is formed by silica tube sandwiched two microstructured fibers (MFs). The reported here can be fabricated at low cost, possess robust structure, and has capability. micro-sized holes in the MFs naturally function as channels through liquid samples efficiently conveniently delivered into out of FP cavity pressure/vacuum pump system for high-performance RI measurement....

10.1364/oe.21.006633 article EN cc-by Optics Express 2013-03-08

Biomass hard carbon, serving as a negative electrode material for sodium-ion batteries, boasts characteristics such extensive sources, low cost, and high sodium storage capacity, thus earning its reputation as...

10.1039/d4se01617c article EN Sustainable Energy & Fuels 2025-01-01

In vivo bioluminescence imaging (BLI) has played a more and important role in biomedical research of small animals. Bioluminescence tomography (BLT) further translates the BLI optical information into three-dimensional bioluminescent source distribution, which could greatly facilitate applications related studies. Although diffusion approximation (DA) is one most widely-used forward models, higher-order approximations are still needed for animal imaging. this work, as relatively accurate...

10.1364/oe.18.020988 article EN cc-by Optics Express 2010-09-20

Purpose: Fluorescence‐enhanced optical imaging using near‐infrared (NIR) light developed for in vivo molecular targeting and reporting of various diseases provides promising opportunities diagnostic imaging. However, the measurement sensitivity NIR fluorescence (NIRF) systems is limited by leakage strong backscattered excitation through rejection filters. In this article, authors present a systematic method improving validating NIRF imager currently used clinical human lymphatic function....

10.1118/1.3497153 article EN Medical Physics 2010-10-27

Bioluminescence imaging has been extensively applied to in vivo small animal imaging. Quantitative three-dimensional bioluminescent source information obtained by using bioluminescence tomography can directly and much more accurately reflect biological changes as opposed planar Preliminary simulated experimental reconstruction results demonstrate the feasibility promise of tomography. However, use multiple approximations, particularly diffusion approximation theory, affects quality...

10.1088/0031-9155/54/21/003 article EN Physics in Medicine and Biology 2009-10-09

Fluorescence molecular imaging/tomography may play an important future role in preclinical research and clinical diagnostics. Time- frequency-domain fluorescence imaging can acquire more measurement information than the continuous wave (CW) counterpart, improving image quality of tomography. Although diffusion approximation (DA) theory has been extensively applied optical imaging, high-order photon migration models need to be further investigated match quantitation provided by nuclear...

10.1088/0031-9155/55/16/002 article EN Physics in Medicine and Biology 2010-07-30

ABSTRACT: Horizontal–vertical (H–V) reinforcing elements are a new type of soil reinforcement in geotechnical engineering. The advantages this have been validated by series triaxial compression tests which all the three principal stresses play role stress–strain–strength response. However, many designs involve mass subjected to plane strain conditions. In paper, laboratory were carried out with different heights vertical inclusions along horizontal under four confining stresses. order gain...

10.1680/gein.13.00009 article EN Geosynthetics International 2013-06-01

Bioluminescence imaging is a very sensitive modality, used in preclinical molecular imaging. However, its planar projection form, it non-quantitative and has poor spatial resolution. In contrast, bioluminescence tomography (BLT) promises to provide three dimensional quantitative source information. Currently, nearly all BLT reconstruction algorithms use employ the diffusion approximation theory determine light propagation tissues. this process, several approximations assumptions that are...

10.1364/oe.17.016681 article EN cc-by Optics Express 2009-09-03

Bioluminescence imaging, especially planar bioluminescence has been extensively applied in vivo preclinical biological research. tomography (BLT) the potential to provide more accurate imaging information due its 3D reconstruction compared with counterpart.In this work, we introduce a positron emission (PET) radionuclide imaging-based strategy validate BLT results. X-ray computed tomography, PET, spectrally resolved and surgical excision were performed on tumor xenograft mouse model...

10.1007/s11307-010-0332-y article EN cc-by-nc Molecular Imaging and Biology 2010-05-12

Bioluminescence imaging (BLI) makes it possible to elucidate molecular and cellular signatures better understand the effects of human disease in small animal models vivo. The unambiguous three-dimensional bioluminescent source information obtained by bioluminescence tomography (BLT) could further facilitate its applications biomedicine. However, best our knowledge, existing gradient-type reconstruction methods BLT are inefficient, often require a relatively volume interest (VOI) for feasible...

10.1364/oe.18.003732 article EN cc-by Optics Express 2010-02-05

Bioluminescence tomography (BLT) is an inverse source problem that localizes and quantifies bioluminescent probe distribution in 3-D. The generic BLT model ill-posed, leading to nonunique solutions aberrant reconstruction the presence of measurement noise optical parameter mismatches. In this paper, we introduce knowledge number bioluminescence sources stabilize problem. Based on regularized model, develop a differential evolution-based algorithm determine locations strengths accurately...

10.1109/tbme.2010.2041452 article EN IEEE Transactions on Biomedical Engineering 2010-02-17

Lactobacillus delbrueckii subsp. bulgaricus (LDB) is an approved feed additive on the Chinese ‘Approved Feed Additives’ list. However, possibility of LDB as antibiotic replacement remains unclear. Particularly, effect microbiota and metabolites in gastrointestinal tract (GIT) requires further explanation. This study aimed to identify present fecal samples investigate relationship between evaluate potential pig production. A total 42 female growing-finishing pigs were randomly allocated into...

10.3390/ani12141778 article EN cc-by Animals 2022-07-11

Tuberculosis (TB) remains a major global disease, and diabetes, which is documented to increase susceptibility TB threefold, also becoming pandemic. This has been attracting extensive research interest. The increased risk of in diabetes may serve as unique model understand host specific pathogens humans. To examine this rationale, we investigated the expression reported candidate genes longitudinal study. Two genes, HK2 CD28, emerged potential culprits diabetes-increased susceptibility.

10.5588/ijtld.11.0536 article EN The International Journal of Tuberculosis and Lung Disease 2012-01-09
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