A5101434506- Epigenetics and DNA Methylation
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Kruppel-like factors research
- MicroRNA in disease regulation
- Reproductive Biology and Fertility
- Lung Cancer Treatments and Mutations
- Renal and related cancers
- Glaucoma and retinal disorders
- RNA modifications and cancer
- Transplantation: Methods and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Monoclonal and Polyclonal Antibodies Research
- Systemic Lupus Erythematosus Research
- Heat Transfer and Optimization
- Ophthalmology and Visual Impairment Studies
- Atherosclerosis and Cardiovascular Diseases
- Corneal surgery and disorders
- Metallic Glasses and Amorphous Alloys
- Aluminum Alloys Composites Properties
- Sirtuins and Resveratrol in Medicine
- Genomics, phytochemicals, and oxidative stress
- Cancer Genomics and Diagnostics
- Renal Transplantation Outcomes and Treatments
- Connexins and lens biology
Naval University of Engineering
2022-2025
Daping Hospital
2025
Army Medical University
2015-2025
Xidian University
2025
The University of Texas Southwestern Medical Center
2022-2024
First Affiliated Hospital of Guangzhou Medical University
2023-2024
State Key Laboratory of Respiratory Disease
2023-2024
Guangzhou Medical University
2023-2024
Affiliated Hospital of Nantong University
2022-2024
Second Affiliated Hospital of Nantong University
2022-2024
The gradual aging of the global population has led to a surge in age-related diseases, which seriously threaten human health. Researchers are dedicated understanding and coping with complexities aging, constantly uncovering substances mechanism related like chronic low-grade inflammation. NOD-like receptor protein 3 (NLRP3), key regulator innate immune response, recognizes molecular patterns associated pathogens injury, initiating an intrinsic inflammatory response. Dysfunctional NLRP3 is...
Abstract Background Tumor-associated inflammation suggests that anti-inflammatory medication could be beneficial in cancer therapy. Loratadine, an antihistamine, has demonstrated improved survival certain cancers. However, the anticancer mechanisms of loratadine lung remain unclear. Objective This study investigates cancer. Methods A retrospective cohort 4,522 patients from 2006 to 2018 was analyzed identify noncancer drug exposures associated with prognosis. Cellular experiments, animal...
This paper aims to investigate the flow characteristics of primary side fluid in a casing once-through steam generator (COTSG) under vertical conditions, providing theoretical support for its design nuclear power plants. The study employs three-dimensional CFD software STAR-CCM+, utilizing Reynolds stress transport turbulent model numerical simulations, and presents method determining fully developed section heat transfer channel based on dimensionless velocity overlap analysis (entrance...
Multiple sclerosis (MS) is a disease induced by demyelination in the central nervous system, and remission period of MS crucial for remyelination. In addition, abnormal levels thyroid hormone (TH) have been identified MS. However, clinic, insufficient attention has paid to role TH period. Indeed, not only functions development brain but also affects myelination. Therefore, it necessary observe effect on remyelination during this A model cuprizone (CPZ) was used function Through weighing...
Recent progress on multi-modal 3D object detection has featured BEV (Bird-Eye-View) based fusion, which effectively unifies both LiDAR point clouds and camera images in a shared space. Nevertheless, it is not trivial to perform camera-to-BEV transformation due the inherently ambiguous depth estimation of each pixel, resulting spatial misalignment between these two features. Moreover, such also inevitably leads projection distortion image features In this paper, we propose novel...
Billions of COVID-19 vaccine doses have been administered to combat the ongoing global pandemic caused by severe acute respiratory syndrome coronavirus-2. While these vaccines are considered safe, with most adverse events being mild moderate and transient, uncommon systemic side effects vaccines, including de novo or re-activation various glomerular diseases recently observed. We report 6 patients who developed tubulointerstitial disease shortly after receiving vaccinations. Five received...
Two-dimensional van der Waals (vdW) heterostructures are potential candidates for clean energy conversion materials to address the global crisis and environmental issues. In this work, we have comprehensively studied geometrical, electronic, optical properties of M2CO2/MoX2 (M = Hf, Zr; X S, Se, Te) vdW heterostructures, as well their applications in fields photocatalytic photovoltaic using density functional theory calculations. The lattice dynamic thermal stabilities designed confirmed....
Using Mendelian Randomization (MR) and large-scale Genome-Wide Association Study (GWAS) data, this study aimed to investigate the potential causative relationship between testosterone sex hormone-binding globulin (SHBG) levels onset of several cancers, including pathway enrichment analyses single nucleotide polymorphisms (SNPs) associated with cancer allowed for a comprehensive bioinformatics approach, which offered deeper biological understanding these relationships. The results indicated...
Since industrialization, global carbon dioxide (CO2) emissions have been rising substantially, playing an increasingly important role in warming and climate change. As the largest CO2 emitter, China has proposed ambitious reduction plan of peaking before 2030 achieving neutrality by 2060. Calculation inventories at regional scales (e.g., city county) great significance terms China’s policies as well national targets. However, most existing data were calculated based on fossil fuel...
Objective To discover novel serum biomarkers that have diagnostic or predictive value in lupus nephritis (LN). Methods Using a quantitative protein microarray, we screened for high‐abundant proteome expression the of patients with LN compared to healthy controls. Top candidates from this screening were validated using larger cohort disease control (subjects other chronic kidney diseases) and cohort. Promising markers then selected machine‐learning model further patient The corresponding...
Brassica rapa L. (BR), a traditional biennial herb belonging to the species of Brassicaceae, has been widely used for functions anti-inflammatory, antitumor, antioxidation, antiaging, and regulation immunity. In this study, antioxidant activity protective effects on H2O2-induced oxidative damage in PC12 cells active fractions BR were investigated vitro. Among all fractions, ethyl acetate fraction ethanol extract from (BREE-Ea) showed strongest activity. Additionally, it was noted that...
In order to search for novel antitumor drugs with high efficiency and low toxicity, the anti-lung cancer activity of phytosphingosine was studied. Phytosphingosine is widely distributed in fungi, plants, animals, has several biological activities, including anti-inflammation anti-tumor. However, its needs be further investigated. The effects pharmacological mechanisms on lung treatment were investigated both vitro vivo. results showed that inhibited growth cell lines. induced apoptosis...
Uncorrected refractive error (URE) is one of the main causes visual impairments. URE may reduce interaction and learning in classroom, leading to social isolation, irreversible amblyopia, lack external knowledge, restrictions on education employment opportunities. Our aim was investigate prevalence related factors adolescents using epidemiological surveys questionnaire lifestyle habits.
To solve the problem of difficulty in identifying apple diseases natural environment and low application rate deep learning recognition networks, a lightweight ResNet (LW-ResNet) model for disease is proposed. Based on residual network (ResNet18), multi-scale feature extraction layer constructed by group convolution to realize compression improve ability different sizes lesion features. By improving identity mapping structure reduce information loss. introducing efficient channel attention...
Myopia is an increasingly serious health problem in China. The aim of this study was to investigate the prevalence myopia and factors associated with it among students Nantong, China, show current status prevention.This school-based, cross-sectional examined from all high schools urban area At least two classes were randomly selected each grade school. A self-reported questionnaire used collect required information. Univariate analyses performed identify associations between various...
This study aims to analyze the indoor environment preferences of Chinese urban elderly, create a living that is beneficial physical and mental health enhance their sense well-being. Based on an in-depth 306 elderly’s bedroom preference in 21 provinces, using questionnaire method, this concludes that: (1) Group characteristics: for key words color lighting are low saturation, bright, warm tones white light; personal characteristics such as gender, condition, education have strong correlation...