A5054389482- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Hemoglobinopathies and Related Disorders
- Psychosomatic Disorders and Their Treatments
- Neonatal and fetal brain pathology
- Genetics and Neurodevelopmental Disorders
- Bacterial Infections and Vaccines
- EEG and Brain-Computer Interfaces
- Childhood Cancer Survivors' Quality of Life
- Pediatric Hepatobiliary Diseases and Treatments
- Anesthesia and Neurotoxicity Research
- Infectious Encephalopathies and Encephalitis
- Pharmaceutical studies and practices
- Palliative Care and End-of-Life Issues
- RNA regulation and disease
- Adolescent and Pediatric Healthcare
- Genomics and Rare Diseases
- Functional Brain Connectivity Studies
- Healthcare Decision-Making and Restraints
- Neurological and metabolic disorders
- Medical Imaging and Analysis
- Interpreting and Communication in Healthcare
- Health Sciences Research and Education
- Polyomavirus and related diseases
- Patient Safety and Medication Errors
Nationwide Children's Hospital
2018-2024
Virginia Commonwealth University
2022-2024
Stanford University
2024
Mayo Clinic
2024
The Ohio State University
2024
University of California, Los Angeles
2009-2024
Cleveland Clinic
2024
University of Minnesota
2024
American Academy of Neurology
2024
National Institute of Neurological Disorders and Stroke
2024
OBJECTIVE: We compared associations of epilepsy remission status and severity as well psychiatric other comorbidities with child parent-proxy reports health-related quality life (HRQoL) in adolescents previously diagnosed epilepsy. METHODS: In a prospective, community-based study newly childhood epilepsy, HRQoL 277 children was assessed 8 to 9 years after diagnosis by using versions the Child Health Questionnaire (CHQ). Multiple linear regression models adjusted for age gender were used...
Epilepsy is a common condition in the United States. It estimated that 1.2% of population or 3.4 million people have epilepsy. This figure may be underestimated because potential repercussions and stigma disclosing epilepsy.1 Studies shown with epilepsy are more likely to unemployed unable work, lower annual household incomes, obese physically inactive, less marry.2,3 People can poor overall health status, impaired intellectual physical functioning, elevated risk accidents injuries, negative...
Summary Purpose Delayed diagnosis of early onset epilepsy is a potentially important and avoidable complication in care. We examined the frequency diagnostic delays young children with newly presenting epilepsy, their developmental impact, reasons for delays. Methods Children who developed before third birthday were identified prospective community‐based cohort. An interval ≥1 month from second seizure to was considered delay. Testing development at baseline up 3 years after intelligence...
<h3>Objective:</h3> To identify clinical and nonclinical factors associated with time from epilepsy onset to surgical evaluation treatment among a cohort of children having surgery. <h3>Methods:</h3> Data were abstracted records 430 (younger than 18 years) who had neurosurgery at the University California, Los Angeles 1986 2010. Multivariable Cox proportional hazards models used analyze unique associations severity, pre-referral brain MRI, sociodemographic characteristics <h3>Results:</h3>...
Seizure freedom is the goal for patients who experience seizures and physicians treatment teams provide care these patients. In 2017, American Academy of Neurology Institute (AANI) seated a standing epilepsy quality measure development work group charged with developing appropriate improvement measures seizures. 2018, released an updated measurement set that included seizure frequency initially published in 2014 set.1,2 2018 publication, noted future effort was needed to move toward more...
Summary Objective Although shorter time to pediatric resective epilepsy surgery is strongly associated with greater disease severity, other nonclinical diagnostic and sociodemographic factors also play a role. We aimed examine parent‐reported barriers timely receipt of surgery. Methods conducted 37 interviews parents children who previously had at University California Los Angeles ( UCLA ; 2006–2011). Interviews were audio‐recorded, transcribed, systematically coded using thematic analysis...
Adults with childhood-onset epilepsy experience poorer adult social outcomes than their peers. The relative roles of seizures over time versus learning and psychiatric problems are unclear.We examined independent influences disorders seizure course in 241 young adults (22-35 years old) uncomplicated a longitudinal community-based cohort study. Social were ascertained throughout the A history was ∼9 after study entry. Seizure was: "Excellent," no first year, complete remission at last contact...
BACKGROUND: It is unclear if socioeconomic factors like type of insurance influence time to referral and developmental outcomes for pediatric patients undergoing epilepsy surgery. OBJECTIVE: This study determined whether private compared with state government was associated shorter intervals seizure onset surgery better quotients METHODS: A consecutive cohort (n = 420) were retrospectively categorized into those Medicaid (California Children's Services; n 91) or (Preferred Provider...
Aim To determine whether early measures of adaptive behavior are predictive later school difficulties and achievement in otherwise neurotypical (unimpaired) children with onset epilepsy during the preschool years. Method In a prospective cohort study, parents completed V ineland A daptive B ehavior S cales ( VABS ) for who were aged 5 years or less at diagnosis. Eight to 9 later, assessed using W echsler I ntelligence C hildren WISC ), ide R ange chievement T est WRAT hild hecklist CBCL )....
Accurate and complete racial/ethnic data in the electronic health record are a requisite step to addressing disparities neurologic care, at local, regional, national levels. The current pertaining patients' race ethnicity contained inadequate. This article outlines recommendations individual practice vendor level improve documentation of ethnicity.
Abstract Objective Epilepsy is associated with significant mortality risk. There limited research examining how traumatic brain injury (TBI) timing affects in relation to the onset of epilepsy. We aimed assess temporal relationship between epilepsy and TBI regarding a cohort post‐9/11 veterans. Methods This retrospective study included veterans who received health care Defense Health Agency Veterans Administration 2000 2019. For those diagnosed epilepsy, index date was first antiseizure...
Penetrating traumatic brain injury (TBI) is a well-established risk factor for post-traumatic epilepsy (PTE). However, many veterans in Operation Enduring Freedom (OEF) and Iraqi (OIF) who suffer from TBI do so blast injury, its consequences are not fully known. Two neurologists performed chart review to describe patterns of health care among all 16 OEF/OIF at the VA Greater Los Angeles Healthcare System were assigned an outpatient diagnosis both 2008–2009. All Veterans male, mean age was 30...
Summary Objective We aimed to compare long‐term social outcomes in young adults with childhood‐onset epilepsy (cases) neurologically normal sibling controls. Methods Long‐term were assessed at the 15‐year follow‐up of Connecticut Study Epilepsy, a community‐based prospective cohort study children newly diagnosed epilepsy. Young complicated (abnormal neurologic exam findings, abnormal brain imaging lesion referable epilepsy, intellectual disability ( ID ; IQ < 60) or informative history...
The age-adjusted prevalence of seizure disorder in United States veterans deployed Iraq and Afghanistan conflicts (IAV) is 6.1 per 1,000 persons (1), compared with 7.1 to 10 the general population (2,3). Persons epilepsy are at risk excess mortality part because comorbidity (4). Although patterns have been associated IAV (5), unique contribution unknown. A cohort study was developed using inpatient, outpatient, pharmacy data from U.S. Department Veterans Affairs, Health Administration (VA)...
Traumatic brain injury (TBI) is a well-established epilepsy risk factor and common among service members. Deployment-related TBI, where combat/blast may be more common, have different outcomes than nondeployment-related TBI. This work examined associations of all TBI exposures (not just combat), epilepsy, while adjusting for comorbidities associated with veterans by deployment status.