A5104280335- Magnetic and Electromagnetic Effects
- Drug-Induced Hepatotoxicity and Protection
- Cannabis and Cannabinoid Research
- Freezing and Crystallization Processes
- Liver Disease Diagnosis and Treatment
- Microbial Metabolites in Food Biotechnology
- Liver physiology and pathology
- Adipose Tissue and Metabolism
- Peroxisome Proliferator-Activated Receptors
- Asymmetric Hydrogenation and Catalysis
- Metal complexes synthesis and properties
- Electrochemical Analysis and Applications
- Autophagy in Disease and Therapy
- Arsenic contamination and mitigation
- Ocular Infections and Treatments
- Light effects on plants
- PARP inhibition in cancer therapy
- Calcium signaling and nucleotide metabolism
- Inflammasome and immune disorders
- Organophosphorus compounds synthesis
- Long-Term Effects of COVID-19
- Medicinal Plants and Neuroprotection
- Virus-based gene therapy research
- Carcinogens and Genotoxicity Assessment
- Heme Oxygenase-1 and Carbon Monoxide
Nanjing Municipal Center for Disease Control And Prevention
2024-2025
Nanjing Medical University
2019-2024
Jiangnan University
2023-2024
Jilin University
2024
State Key Laboratory of Food Science and Technology
2024
Sun Yat-sen University
2020-2023
Fifth Affiliated Hospital of Sun Yat-sen University
2021-2022
Shanghai Institute of Pollution Control and Ecological Security
2022
State Key Laboratory of Pollution Control and Resource Reuse
2022
Tongji University
2022
Wnt signaling is one of the key regulators hepatocellular carcinoma (HCC) tumor progression. In addition to classical receptor frizzled (FZD), various coreceptors including heparan sulfate proteoglycans (HSPGs) are involved in activation. Glypican‐3 (GPC3) an HSPG that overexpressed HCC and functions as a coreceptor modulates cell proliferation. These features make GPC3 attractive target for liver cancer therapy. However, precise interaction how GPC3, Wnt, FZD cooperate with each other...
Currently, there are no effective therapies for liver fibrosis; hence, the development of anti-liver fibrosis agents is urgently needed. Here, we attempted to investigate therapeutic effect and mechanism asiatic acid (AA) on fibrosis, mainly focusing impact AA nuclear erythroid 2-related factor 2/antioxidant response element (Nrf2/ARE), factor-kappa B (NF-κB)/IκBα, JAK1/signal transducer activator transcription 3 (STAT3) signaling pathways.Rats were induced by carbon tetrachloride (CCl4) 6...
Glioblastoma (GBM) is an extremely deadly form of brain cancer with limited treatment options and thus novel therapeutic modalities are necessary. Histone deacetylase inhibitors (HDACi) have demonstrated clinical preclinical activities against GBM. (Silent mating type information regulation 2 homolog, Sirt1) abbreviated as Sirtuin 1, has been implicated in We explored the activity Sirt1 activator SRT2183 glioma cell lines terms biological response.The effects on growth neurosphere survival...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis, isomer separation, and metal complexation studies of aza- oxaphosphands, a class hard/soft dinucleating phosphine macrocyclesLiwen Wei, Andrew Bell, Kwang Hyun Ahn, Mark M. Holl, Steve Warner, Ian D. Williams, Stephen J. LippardCite this: Inorg. Chem. 1990, 29, 4, 825–837Publication Date (Print):February 1, 1990Publication History Published online1 May 2002Published inissue 1 February...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAza- and oxaphosphands, a new class of hard/soft binucleating phosphine macrocyclesLiwen. Wei, Andrew. Bell, Steve. Warner, Ian D. Williams, Stephen J. LippardCite this: Am. Chem. Soc. 1986, 108, 26, 8302–8303Publication Date (Print):December 1, 1986Publication History Published online1 May 2002Published inissue 1 December 1986https://pubs.acs.org/doi/10.1021/ja00286a051https://doi.org/10.1021/ja00286a051research-articleACS PublicationsRequest...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInduced Internal Electron Transfer Chemistry in Rhenium Sulfide SystemsHenry H. Murray, Liwen Wei, Suzanne E. Sherman, Mark A. Greaney, Kenneth Eriksen, Barbara Carstensen, Thomas R. Halbert, and Edward I. StiefelCite this: Inorg. Chem. 1995, 34, 4, 841–853Publication Date (Print):February 1, 1995Publication History Published online1 May 2002Published inissue 1 February...
Acute kidney injury (AKI) is the most serious adverse reaction during cisplatin chemotherapy, which limits drug's clinical effects. Therefore, effective strategies for protective therapy need to be developed. In current study, we verified that tetrahedral DNA nanostructures (TDNs), promising nano biomaterials, played roles against cisplatin-induced death of renal tubular cells. Herein, observed TDNs decreased generation lipid reactive oxygen species (ROS), restored down-regulation...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBridging Disulfido Complexes of Molybdenum and Tungsten Formed by Reductive Sulfurization Oxo-Molybdenum(VI) Desulfurization Thio(disulfido)-Tungsten(VI) ComplexesCharles G. Young, Teresa O. Kocaba, Xue F. Yan, Edward R. T. Tiekink, Liwen Wei, Henry H. Murray III, Catherine L. Coyle, I. StiefelCite this: Inorg. Chem. 1994, 33, 26, 6252–6260Publication Date (Print):December 1, 1994Publication History Published online1 May 2002Published inissue 1...
Polychlorinated biphenyls (PCBs) are persistent organic pollutants with continued public health concerns. The lower chlorinated supposed to be mutagenic following metabolic activation. However, in a preliminary study, we recently observed induction of micronuclei by several PCBs subclone Chinese hamster V79 cell line, V79‐Mz, which is deficient xenobiotic‐metabolizing enzyme activities. In this metabolism‐free genotoxicity was investigated, using 10 tri‐ and tetrachlorobiphenyls, V79, human...
A simple technique for the identification of common genotypes hepatitis B virus (HBV) remains to be identified. The present study was conducted establish such a methodology. Four plasmids A‑D and 123 clinical serum specimens HBV‑infected patients were genotyped. HBV would detected successfully when genotype reached viral load 1 x 103 copies/ml or BC mixed samples 5% level. lower limit detection DNA in determined 2.14x102 IU/ml. assay sensitivity specificity 100% consistency demonstrated...
Abstract The interactions of the ligand N , ‐bis‐(β‐carbamoylethyl)‐ethylenediamine (BCEN) with copper (II) in aqueous solution have been investigated by potentiometric and spectrophotometric techniques. two protonation constants at 25° 0.2 M NaNO 3 are 10 5‐51 5‐44 quantitative equilibrium studies stepwise reactions which precede formation CuBCEN 2+ Cu‐O to Cu‐N bond rearrangements amide sites described detail. Electronic spectra chelates formed measured discussed.