A5101993254- Thyroid Disorders and Treatments
- Nanoparticles: synthesis and applications
- Reproductive System and Pregnancy
- Heavy Metal Exposure and Toxicity
- MicroRNA in disease regulation
- Plant Molecular Biology Research
- Osteoarthritis Treatment and Mechanisms
- Connective tissue disorders research
- Bone Metabolism and Diseases
- Photosynthetic Processes and Mechanisms
- Human Health and Disease
- Neuropeptides and Animal Physiology
- Selenium in Biological Systems
- Reproductive Biology and Fertility
- Circadian rhythm and melatonin
- Syphilis Diagnosis and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Polysaccharides and Plant Cell Walls
- TGF-β signaling in diseases
- Mosquito-borne diseases and control
- Genetics, Aging, and Longevity in Model Organisms
- Thyroid Cancer Diagnosis and Treatment
- Protein Hydrolysis and Bioactive Peptides
- Neuroendocrine regulation and behavior
- Endometriosis Research and Treatment
Beijing Normal University
2023-2024
Guangzhou University of Chinese Medicine
2021-2022
Jinan University
2015-2021
Hainan University
2016
Tianjin Medical University
2005-2008
As one popular fresh fruit, banana (Musa acuminata) is cultivated in the world's subtropical and tropical areas. In recent years, pathogen Fusarium oxysporum f. sp. cubense (Foc) has been widely rapidly spread to areas, causing substantial yield loss. However, molecular mechanism of response Foc remains unclear, functional identification disease-related genes also very limited. this study, nine 90 kDa heat-shock proteins (HSP90s) were genomewide identified. Moreover, expression profile them...
Damaged cartilage has very low regenerative potential which led to the search for novel tissue-engineering approaches help treat defects. While various have been reported, there is no perfect treatment currently. In this study we evaluated effects of a plant extract, chlorogenic acid (CGA), as part chondrocyte transplantation on model knee joint injury in chicks. First, primary cultured chondrocytes used evaluate CGA chondrogenesis. Then using an articular chick assessed functional recovery...
Zinc oxide nanoparticles (ZnO NPs) have been increasingly and widely utilized in various fields, such as agriculture, food cosmetics. However, levels of adverse impacts ZnO NPs on the ecological environment public health associated with each stage their production, use disposal. can be ingested by pregnant women transferred to developing embryos/foetus through placental barrier, however, potential toxicity embryonic foetal development is largely unclear. In this study, we discovered that...
Dexamethasone (Dex) is commonly used in the treatment of a variety benign and malignant conditions. Unfortunately, although it has teratogenic effects, remains clinical practice for pregnant women mainly due to limited alternatives. However, there knowledge mechanisms that lead observed effects. In this study, effects Dex during embryogenesis on neural crest development were evaluated early chick embryos. First, we demonstrated 100 µl 10−6 M leads craniofacial developmental defects, also...
Dexamethasone (Dex) is widely used to treat chronic inflammatory diseases in the clinic. Increasingly, there more attention being paid side effect of Dex. In this study, we investigated involvement and mechanism Dex exposure accelerating mineralization during long bone formation. We first determined that could accelerate vivo, but was no apparent difference between control Dex-treated phalanges model vitro. Next, established promoted angiogenesis chick yolk sac membrane model. addition, it...
Microtubules rely on dynamic assembly and disassembly for their functions. Increasing evidences support that the damage-repair of microtubule lattices can affect dynamics in vitro animal cells. Here we successfully established a way visualizing sites plant cells, via labeling tubulin proteins with photoconvertible fluorescent protein mEOS3.2. We observed crossovers lattice were more prone to be damaged repaired, frequency events positively correlated crossing angle between microtubules. The...
Phenobarbital is an antiepileptic drug that widely used to treat epilepsy in a clinical setting. However, long term of phenobarbital administration pregnant women may produce side effects on embryonic skeletogenesis. In this study, we aim investigate the mechanism by which treatment induces developmental defects bones. We first determined decreased chondrogenesis and inhibited proliferation chondrocytes chick embryos. also suppressed mineralization both vivo vitro bone models. Next,...
With the wide application of nanometer materials in daily life, people pay more attention to potential toxicity nanoparticles human fetal development once are absorbed into body during pregnancy. However, there was no directly solid evidence for ZnO NPs-caused congenital heart defects. Hence, we investigated effect NPs exposure on early cardiogenesis using chicken/mouse embryo models. First, showed reduced H9c2 cell viability a dose- and time-dependent manner, while autophagy significantly...