A5102913684- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Heparin-Induced Thrombocytopenia and Thrombosis
- Venous Thromboembolism Diagnosis and Management
- Sepsis Diagnosis and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma Management and Diagnosis
- Blood transfusion and management
- Hemophilia Treatment and Research
- Nerve Injury and Rehabilitation
- Erythropoietin and Anemia Treatment
- Acute Ischemic Stroke Management
- Clinical Laboratory Practices and Quality Control
- Atrial Fibrillation Management and Outcomes
- Trauma and Emergency Care Studies
- Hemodynamic Monitoring and Therapy
- Case Reports on Hematomas
- Antiplatelet Therapy and Cardiovascular Diseases
- Anesthesia and Pain Management
- Cardiac and Coronary Surgery Techniques
- Medical and Biological Ozone Research
- Complement system in diseases
- Healthcare cost, quality, practices
- Frailty in Older Adults
Groote Schuur Hospital
2017-2024
University of Cape Town
2017-2024
McMaster University
2002-2021
Southmead Hospital
2016-2021
North Bristol NHS Trust
2011-2021
Impact
2018-2019
St. Joseph’s Healthcare Hamilton
2007-2017
Jagiellonian University
2017
London Health Sciences Centre
2017
Coventry University
2017
BackgroundManipulation under anaesthesia and arthroscopic capsular release are costly invasive treatments for frozen shoulder, but their effectiveness remains uncertain. We compared these two surgical interventions with early structured physiotherapy plus steroid injection.MethodsIn this multicentre, pragmatic, three-arm, superiority randomised trial, patients referred to secondary care treatment of primary shoulder were recruited from 35 hospital sites in the UK. Participants adults (≥18...
Critical illness represents a major global health-care burden and critical care is an essential component of hospital care. There are few data describing the prevalence, treatment, outcomes critically ill patients in African hospitals. This was international, prospective, point prevalence study acute hospitals across Africa. Investigators examined all inpatients aged 18 years or older, regardless location, to assess coprimary 7-day mortality. Patients were classified as if at least one vital...
Although guidelines for fresh frozen plasma (FFP) use have been published, many transfusions are considered inappropriate. Current suggest few circumstances in which FFP transfusion to critically ill patients is warranted. The objectives of this study were evaluate the consistency Canadian administration and examine factors associated with inappropriate transfusions.Retrospective cohort study.15-bed medical surgical intensive care unit a teaching hospital.254 consecutive adults admitted...
Mothers in Africa are 50 times more likely to die after cesarean delivery (CD) than high-income countries, largely due hemorrhage. It is unclear whether countries across adequately equipped prevent and treat postpartum hemorrhage (PPH) during CD.
Objective To assess the psychometric properties of Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire. Methods This study was a cross-sectional, multinational study. Participants were enrolled if they more than 10 years old people with haemophilia A or B without bleeding disorder. invited through non-governmental patient organisations in 21 countries between 01/27/2016 02/23/2017. The following properties: missing data, floor ceiling effects, exploratory factor analysis...
Abstract Background Clavicle fractures account for around 4% of all and up to 44% the shoulder girdle. Fractures middle third (or mid-shaft) approximately 80% clavicle fractures. Management this group is often challenging outcome can be unsatisfactory. In particular it not clear whether surgery produces better outcomes than non-surgical management. Currently there much variation in use a lack good quality evidence inform our decision. Methods/Design We aim undertake multicentre randomised...
Although dislocation of the shoulder is a relatively common event, overwhelming majority injuries are anterior. Posterior more uncommon, comprising between 3% and 5% all dislocations. One percent dislocations involve fracture, whereas only 0.9% 1500 cases reported by Neer (J Bone Joint Surg Am 1970; 52:1077-89; J 52:1090-103) concerned posterior fracture Bilateral an even rarer just Given rarity relative poor outcome often observed after these severe injuries, it important that upper limb...
Abstract Background The Patient Reported Outcomes Burdens and Experience (PROBE) study has developed validated the PROBE questionnaire for assessing patient‐reported outcomes in people with haemophilia participants without bleeding disorders. Objective To explore regional variations international implementation of questionnaire. Methods Data were collected from four regions (Western Pacific, South America, North America Europe). Participants able to choose English or translated versions into...
Background Manual segmentations of intracranial hemorrhage on non-contrast CT images are the gold-standard in measuring hematoma growth but prone to rater variability. Aims We demonstrate that a convex optimization-based interactive segmentation approach can accurately and reliably measure growth. Methods Baseline 16-h follow-up head 46 subjects presenting with were selected randomly from ANNEXA-4 trial imaging database. Three users semi-automatically segmented volume for each timepoint...
Platelet dysfunction has a major contribution in bleeding after cardiopulmonary bypass (CPB) and transfusion of platelets is frequently used to secure haemostasis. Allogeneic prepared for are functionally impaired. Autologous harvested preoperatively require shorter storage time before their use also avoids the risks associated with allogeneic blood products. For first time, we have compared functional quality autologous by two methods, immediately infusion. activation was assessed...
Various definitions of bleeding have been used in perioperative studies without systematic assessment the diagnostic criteria for their independent association with outcomes important to patients. Our proposed definition impacting mortality after noncardiac surgery (BIMS) is that independently associated death during or within 30 days surgery. We describe our analysis plan sequentially 1) establish BIMS, 2) estimate contribution BIMS 30-day and 3) develop internally validate a clinical...
Purpose: Preparing bone marrow smears using non-anticoagulated aspirate is a traditional practice but many laboratories now use anticoagulated samples in K-EDTA. There are no published studies comparing the effectiveness of these two methods. This report compares readability slides, prepared and methods, from three Hamilton Ontario. Methods: A blinded set 129 slides methodologies (using K-EDTA) was reviewed by reviewers. Slides were classified as unreadable if observers rejected them based...
Background Blockade of the suprascapular nerve (SSN) is used frequently in shoulder surgery and chronic pain. Anatomical landmarks may be to locate before infiltration with local anaesthetic, ultrasound comprising a popular method for locating nerve. Methods Twelve cadaveric shoulders from six specimens were injected dye using both landmark technique. The scanned by computed tomography (CT) then dissected determine accuracy each Results Using CT scan results, we found group more accurate...
Total shoulder arthroplasty is an established treatment with the commonest cause of failure loosening glenoid component. Hydroxyapatite metal-backed components could offer better survivorship due to improved fixation. The aim this study was investigate periprosthetic radiolucency rates associated uncemented, polyethylene component medium-term results.A single centre retrospective examining radiological outcomes Epoca Radiographs were analysed for post-operative adequacy seating and...
SOCIETY OF CRITICAL CARE MEDICINE 32ND CONGRESS SAN ANTONIO, TEXAS, USA JANUARY 28-FEBRUARY 2, 2003: ORAL/SANDWICH PRESENTATIONS: Poster Presentation: Clinical Science: Cardiovascular Technique: PDF Only
We report the clinical case of a septic patient with antiphospholipid syndrome who developed ischemia in all 4 limbs, despite normal systemic blood pressure. Prolonged coagulation times suggested hemorrhagic diathesis, requiring transfusion fresh-frozen plasma and discontinuation heparin infusion. In contrast, study viscoelastic properties clot by thromboelastography an uncontrolled activation cascade. This observation led to reintroduction improvement patient’s laboratory findings....
Knowledge about sexual health, difficulty with activity and intimacy (sexual difficulty), in people hemophilia is little understood.The objectives were to determine the prevalence of living (PWH) compared no bleeding disorders (PWNoBD), factors associated it.This was an analysis PROBE study. We recruited individuals who had A or B PWNoBD 18 years old older. calculated proportions participants odds ratios (ORs) adjusted for sex age 95% confidence intervals.There 2007 PWH 1972 PWNoBD. Mean...