A5069597135- SARS-CoV-2 and COVID-19 Research
- Parasitic Infections and Diagnostics
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Animal Virus Infections Studies
- COVID-19 and Mental Health
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Endometriosis Research and Treatment
- Parasite Biology and Host Interactions
- Geriatric Care and Nursing Homes
- Plant Virus Research Studies
- Immune responses and vaccinations
- vaccines and immunoinformatics approaches
- COVID-19 and healthcare impacts
- Mollusks and Parasites Studies
- Helminth infection and control
- Genomics and Phylogenetic Studies
- Dermatological diseases and infestations
- Study of Mite Species
- COVID-19 epidemiological studies
- Insect and Pesticide Research
- Inflammasome and immune disorders
Cardiff University
2021-2025
Institute of Biological, Environmental and Rural Sciences
2016-2020
Aberystwyth University
2019-2020
Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone public health response to COVID-19. The emergence hypermutated, increasingly transmissible variants concern (VOCs) threaten this strategy. Omicron (B.1.1.529), fifth VOC be described, harbours multiple amino acid mutations in spike, half which lie within receptor-binding domain. Here we demonstrate substantial evasion neutralization by BA.1 and BA.2 vitro using sera from individuals vaccinated with ChAdOx1, BNT162b2...
Cryptosporidium, a protozoan parasite of significant public health concern, is responsible for severe diarrheal diseases, particularly in immunocompromised individuals and young children resource-limited settings. Analysis whole genome next generation sequencing (NGS) data critical step improving our understanding Cryptosporidium epidemiology, transmission dynamics, genetic diversity. However, effective analysis NGS context necessitates the development robust, validated bioinformatics tools....
2. Abstract Cryptosporidium, a protozoan parasite of significant public health concern, is responsible for severe diarrheal disease, particularly in immunocompromised individuals and young children resource-limited settings. Analysis whole genome next generation sequencing (NGS) data critical improving our understanding Cryptosporidium epidemiology, transmission, diversity. However, effective analysis NGS context necessitates the development robust, validated computational tools. We present...
Parasitic nematodes that affect the respiratory system of felids are spreading in endemic regions and emerging areas hosts which were previously free them. Recent reports lungworm parasitoses caused by Aelurostrongylus abstrusus, Troglostrongylus brevior Eucoleus aerophilus have stimulated an increase scientific interest biology, ecology epidemiology these nematodes. The majority literature dedicated to feline metastrongylid lungworms has been focused on A. mainly because it is most commonly...
Abstract Genomics is amongst the most powerful tools available for mounting a clinical response to infectious disease. The accurate and precise taxonomic evaluation of pathogens essential when building picture pathogenicity, virulence, transmission, drug resistance. Carrying out such profiling in high throughput manner necessitates development reliable bioinformatic tools. Here we present Afanc, novel metagenomic profiler which sensitive down species strain level taxa, capable elucidating...
Ectoparasite infections caused by mites present a consistent and frequent challenge to veterinary practitioners. Of the estimated 0.5–1 million mite species on earth, there is subgroup that are parasitic can cause major disease. These parasites pose challenges such as mis-identification limited treatment options, well need change husbandry practices prevent transmission. of companion animals, burrowing particular importance due their propensity mange in infested host. The most important...