Helen Adams
A5048641306- Climate Change, Adaptation, Migration
- SARS-CoV-2 and COVID-19 Research
- Disaster Management and Resilience
- Land Use and Ecosystem Services
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Conservation, Biodiversity, and Resource Management
- Crystallography and molecular interactions
- COVID-19 Clinical Research Studies
- Coastal and Marine Management
- SARS-CoV-2 detection and testing
- Animal Virus Infections Studies
- Migration and Labor Dynamics
- COVID-19 epidemiological studies
- Urban Transport and Accessibility
- Migration, Aging, and Tourism Studies
- Place Attachment and Urban Studies
- Water-Energy-Food Nexus Studies
- Climate change impacts on agriculture
- Clostridium difficile and Clostridium perfringens research
- Water resources management and optimization
- Coastal wetland ecosystem dynamics
- Nosocomial Infections in ICU
- Tropical and Extratropical Cyclones Research
- Climate Change and Health Impacts
King's College London
2016-2024
University of Bern
2024
University of Dundee
2023
Bangladesh University of Engineering and Technology
2023
University of Bath
2023
University of Exeter
2013-2023
University of Southampton
2023
Betsi Cadwaladr University Health Board
2018-2022
National Institute for Health Research
2021-2022
Government of the United Kingdom
2022
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive a selective advantage but may also be due to random founder effect. We investigate hypothesis for positive selection in United Kingdom using more than 25,000 whole genome sequences. Despite availability large dataset, well represented by both 614 variants, not all approaches showed conclusive signal selection. Population genetic analysis indicates that 614G increases relative 614D manner...
Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone public health response to COVID-19. The emergence hypermutated, increasingly transmissible variants concern (VOCs) threaten this strategy. Omicron (B.1.1.529), fifth VOC be described, harbours multiple amino acid mutations in spike, half which lie within receptor-binding domain. Here we demonstrate substantial evasion neutralization by BA.1 and BA.2 vitro using sera from individuals vaccinated with ChAdOx1, BNT162b2...
The SARS-CoV-2 delta (B.1.617.2) variant was first detected in England March, 2021. It has since rapidly become the predominant lineage, owing to high transmissibility. is suspected that associated with more severe disease than previously dominant alpha (B.1.1.7) variant. We aimed characterise severity of compared by determining relative risk hospital attendance outcomes.
We describe a novel integrated modelling system aiming to approximate the impact of environmental change on farmers' livelihoods in Bangladesh.
Significance Effective environmental policy requires public participation in management, typically achieved through engaging community defined by residential location or resource use. However, current social and change, particularly increasing connectedness, demands new approaches to community. We draw on place attachment theory redefine the context of Australia’s Great Barrier Reef. Using a large dataset attachment, our analysis local, national, international stakeholders identified four...
Planned relocation has been shown to have significant impacts on the livelihoods and wellbeing of people communities, whether resettlement process is inclusive or coercive. For states, planned represents risks those communities but also government investments political legitimacy. Evaluations relocations commonly focus benefits interventions while overlooking consequences not intervening. Here we develop a conceptual framework examine factors that influence decision-making about undertake...
Sea level rise will expose millions of people to increasing coastal hazards and eventual land loss. Thus, it is important understand how residents make decisions about whether when move away with exposure. Historically, non-material dimensions human decision-making have been missing from quantitative modelling migration under environmental change. Here, we use behavioural theory the concept an inherent mobility potential define individual stress thresholds, represented in tension between...
We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several nucleocapsid and ORF3a have arisen independently in multiple lineages result loss of recognition epitope-specific cells assessed IFN-γ cytotoxic killing assays. Complete responsiveness was seen due to Q213K the A∗01:01-restricted CD8+ epitope FTSDYYQLY207-215; P13L, P13S, P13T B∗27:05-restricted QRNAPRITF9-17; T362I P365S A∗03:01/A∗11:01-restricted KTFPPTEPK361-369. lines...
To date, projections of human migration induced by sea-level change (SLC) largely suggest large-scale displacement away from vulnerable coastlines. However, results our model Bangladesh counterintuitively that people will continue to migrate toward the coastline irrespective flooding amplified future SLC under all emissions scenarios until end this century. We developed an empirically calibrated agent-based household decision-making captures multi-faceted push, pull and mooring influences on...
The Delta (B.1.617.2) variant was the predominant UK circulating SARS-CoV-2 strain between May and December 2021. How infection compares with previous variants is unknown. This prospective observational cohort study assessed symptomatic adults participating in app-based COVID Symptom Study who tested positive for from 26 to July 1, 2021 (Delta overwhelmingly variant), compared (1:1, age- sex-matched) individuals presenting 28, 2020 6, (Alpha (B.1.1.7) variant). We illness (symptoms,...
While migration is often conceptualized as an adaptive response to climate hazards, can also present severe risks people on the move. In this paper, we attempt operationalize Representative Key Risks (RKR) framework of Sixth Assessment Report Working Group II Intergovernmental Panel Climate Change (IPCC) for human mobility. First, provide a understanding how mobility emerge by engaging with concept habitability. We argue that uninhabitability occurs where physical environment loses...
Abstract While the benefits humans gain from ecosystem functions and processes are critical in natural resource-dependent societies with persistent poverty, services as a pathway out of poverty remain an elusive goal, contingent on mediated by social processes. Here, we investigate three emerging dimensions service-poverty relationship: economic contribution provisioning to household livelihood mix, social-ecological systems producing different bundles material wealth versus reported life...
Environment migration research has sought to provide an account of how environmental risks and resources affect mobility. Part that effort focused on the role environment in providing secure livelihoods through provisioning ecosystem services. However, many models linkages fail acknowledge importance social psychological factors decision migrate. Here, we seek a more comprehensive model decision-making under change by investigating attachment people form place, creating attachment. We...
Tipping points have gained substantial traction in climate change discourses, both as representing the possibility of catastrophic and irreversible physical societal impacts a way to set motion positive, rapid self-sustaining responses, such adoption new technologies, practices, behaviors. As such, tipping appear ubiquitous natural social systems. Here, we critique 'tipping point' framings, specifically their insufficiency for describing diverse dynamics complex systems; reductionist view...
Abstract This article examines trends in development assistance funding for energy and the implications mitigating climate change. It presents financial data from bilateral multilateral donors during 1997–2005, a period that begins with agreement on Kyoto Protocol under United Nations Framework Convention Climate Change. During this period, aid totalled over US$64 billion or 6–10% of all assistance. Annual was virtually stagnant at approximately US$6–7 1997 to 2005, but preliminary evidence...