A5100715496- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Nutrition and Health in Aging
- Vaccine Coverage and Hesitancy
- Viral Infections and Immunology Research
- SARS-CoV-2 detection and testing
- Body Composition Measurement Techniques
- Mesenchymal stem cell research
- Medical Research and Treatments
- GDF15 and Related Biomarkers
- Blood Pressure and Hypertension Studies
- Anomaly Detection Techniques and Applications
- Cardiovascular Syncope and Autonomic Disorders
- COVID-19 and healthcare impacts
- Misinformation and Its Impacts
- Folate and B Vitamins Research
- Diabetic Foot Ulcer Assessment and Management
- Antimicrobial Resistance in Staphylococcus
- Cardiac electrophysiology and arrhythmias
- Heart Failure Treatment and Management
- Photosynthetic Processes and Mechanisms
- Chronic Disease Management Strategies
- Antiplatelet Therapy and Cardiovascular Diseases
Zhengzhou University
2024
Electric Power Research Institute
2024
Wuhan No.1 Hospital
2024
Wenzhou Medical University
2024
Jinan University
2023
King's College London
2021-2022
Southwest Medical University
2018
Stanford University
2015
Guizhou Provincial People's Hospital
2015
Chung Shan Medical University Hospital
2013
COVID-19 vaccines show excellent efficacy in clinical trials and effectiveness real-world data, but some people still become infected with SARS-CoV-2 after vaccination. This study aimed to identify risk factors for post-vaccination infection describe the characteristics of illness.
Background Mental health issues have been reported after SARS-CoV-2 infection. However, comparison to prevalence in uninfected individuals and contribution from common risk factors (eg, obesity comorbidities) not examined. We identified how COVID-19 relates mental the large community-based COVID Symptom Study. Methods assessed anxiety depression symptoms using two validated questionnaires 413148 between February April 2021; 26998 had tested positive for SARS-CoV-2. adjusted physical...
The Delta (B.1.617.2) variant was the predominant UK circulating SARS-CoV-2 strain between May and December 2021. How infection compares with previous variants is unknown. This prospective observational cohort study assessed symptomatic adults participating in app-based COVID Symptom Study who tested positive for from 26 to July 1, 2021 (Delta overwhelmingly variant), compared (1:1, age- sex-matched) individuals presenting 28, 2020 6, (Alpha (B.1.1.7) variant). We illness (symptoms,...
Background: The Delta (B.1.617.2) SARS-CoV-2 variant was the predominant UK circulating strain between May and November 2021. We investigated whether COVID-19 from infection differed with previous variants in children. Methods: Through prospective COVID Symptom Study, 109,626 school-aged children were proxy-reported 28 December 2020 8 July selected all symptomatic who tested positive for at least weekly, within two timeframes: to 6 2021 (Alpha (B.1.1.7), main variant) 26 (Delta, variant),...
Introduction: Down syndrome (DS) is the leading cause of genetically defined intellectual disability and congenital birth defects worldwide. A large population people diagnosed with DS globally posing an enormous socioeconomic burden. However, global burden trends have not been reported. Methods: Based on data from Global Burden Disease database in 2019, we analyzed incidence, prevalence, disability-adjusted life years (DALYs), death 1990 to 2019 according sex, age, regions,...
Abstract Background The Delta (B.1.617.2) SARS-CoV-2 variant became the predominant UK circulating strain in May 2021. Whether COVID-19 from infection differs to with other variants children is unknown. Methods Through prospective COVID Symptom Study, 109,626 school-aged were proxy-reported between December 28, 2020 and July 8, We selected all symptomatic who tested positive for at least weekly, within two timeframes: 6, 2021 (Alpha (B.1.1.7) main variant); 26 (Delta variant). assessed...
Abstract Background Self-reported symptom studies rapidly increased our understanding of SARS-CoV-2 during the pandemic and enabled monitoring long-term effects COVID-19 outside hospital setting. It is now evident that post-COVID syndrome presents with heterogeneous profiles, which need characterisation to enable personalised care among most affected survivors. This study describes how they relate different viral variants vaccination status. Methods In this prospective longitudinal cohort...
Abstract Background In children, SARS-CoV-2 is usually asymptomatic or causes a mild illness of short duration. Persistent has been reported; however, its prevalence and characteristics are unclear. We aimed to determine duration in symptomatic UK school-aged children tested for using data from the COVID Symptom Study, largest citizen participatory epidemiological study date. Methods Data 258,790 aged 5-17 years were reported by an adult proxy between 24 March 2020 22 February 2021. Illness...
Abstract The Covid Symptom Study, a smartphone-based surveillance study on COVID-19 symptoms in the population, is an exemplar of big data citizen science. As May 23rd, 2021, over 5 million participants have collectively logged 360 self-assessment reports since its introduction March 2020. success Study creates significant technical challenges around effective curation. primary issue scale. size dataset means that it can no longer be readily processed using standard Python-based analytics...
We aimed to explore the effectiveness of one-dose BNT162b2 vaccination upon SARS-CoV-2 infection, its effect on COVID-19 presentation, and post-vaccination symptoms in children adolescents (CA) UK during periods Delta Omicron variant predominance.In this prospective longitudinal cohort study, we analysed data from 115,775 CA aged 12-17 years, proxy-reported through Covid Symptom Study (CSS) smartphone application. calculated infection risk after one dose BNT162b2, described illness profile...
Vitamin B 6 is one of the most versatile cofactors in plants and an essential phytonutrient human diet that benefits a variety health aspects. Although biosynthesis vitamin has been well resolved recent years, main research currently based on Arabidopsis thaliana with very little work done major crop plants. Here we provide first report interactions expression profiles PDX genes for potato how content varies tubers different genotypes. The results demonstrate excellent resource this strong...
Background: Fat deposition is associated with peripheral arterial disease. Adipose tissue has recently been implicated in vascular remodeling and angiogenic activity. We hypothesized that the transplantation of adipose tissues from normal mice improves blood flow perfusion neovascularization high-fat diet fed mice. Methods: After 14 weeks (HFD)-fed mice, unilateral hind limb ischemia was performed. Subcutaneous white (WAT) brown (BAT) fat pads were harvested EGFP subcutaneously transplanted...
Abstract Objective This study aimed to evaluate the incidence of cardiac disorders among children with mid-exertional syncope evaluated by a paediatric cardiologist, determine how often diagnosis was not established, and define potential predictors differentiate from non-cardiac causes. Study design We carried out single-centre, retrospective review who presented for evaluation due history exertional between 1999 2012. Inclusion criteria included following: (1) age ⩽18 years; (2) syncope;...
The purpose of this study was to explore the effects three commonly used positions on grip strength measurement in older people.A total 249 (113 women, 136 men) participants, 72.8 ± 6.5 years old, participated study. Grip (kg) measured positions: (i) standard posture (sitting, elbow flexed 90°) suggested by American Society Hand Therapists; (ii) standing, 90°; and (3) fully extended.One-way repeated measures analysis variance showed that significantly greater standing position with extended...
Abstract Background COVID-19 vaccines show excellent efficacy in clinical trials and real-world data, but some people still contract SARS-CoV-2 despite vaccination. This study sought to identify risk factors associated with infection post-vaccination describe characteristics of illness. Methods Amongst 1,102,192 vaccinated UK adults from the COVID Symptom Study, 2394 (0.2%) cases were identified between 8th December 2020 1st May 2021. Using a control group individuals testing negative, we...
Summary Background Mental health issues have been reported after SARS-CoV-2 infection. However, comparison to prevalence in uninfected individuals and contribution from common risk factors (e.g., obesity, comorbidities) not examined. We identified how COVID-19 relates mental the large community-based COVID Symptom Study. Methods assessed anxiety depression symptoms using two validated questionnaires 413,148 between February April 2021; 26,998 had tested positive for SARS-CoV-2. adjusted...
Abstract Background The Delta (B.1.617.2) variant became the predominant UK circulating SARS-CoV-2 strain in May 2021. How infection compares with previous variants is unknown. Methods This prospective observational cohort study assessed symptomatic adults participating app-based COVID Symptom Study who tested positive for from 26 to July 1, 2021 (Delta overwhelmingly variant), compared (1:1, age- and sex-matched) individuals presenting December 28, 2020 6, (Alpha (B.1.1.7) variant). We...
Abstract Background We aimed to explore the effectiveness of one-dose BNT162b2 vaccination upon SARS-CoV-2 infection, its effect on COVID-19 presentation, and post-vaccination symptoms in children young people (CYP) UK during periods Delta Omicron variant predominance. Methods In this prospective longitudinal cohort study, we analysed data from 115,775 CYP aged 12-17 years, proxy-reported through Covid Symptom Study (CSS) smartphone application. calculated infection risk after one dose...
Abstract Background: The effect of baseline overweight and obesity status on cardiovascular disease(CVD) morbidity adverse outcomes remains unclear. aim this study was to examine the association between overweight, CVD morbidity, mortality, all-cause mortality in Chinese older individuals. Methods: This retrospective cohort analyzed data from electronic health examination records 86,049 individuals aged ≥ 60 years Xinzheng City, Henan Province, China, January 2011 December 2019. Cox...
<title>Abstract</title> <bold>Background</bold> Coronavirus disease 2019 (COVID-19) has led to extensive repercussions on global health and economic systems. In this study, we aim provide an analysis of global, national, regional COVID-19 incidence, mortality, disability-adjusted life years (DALYs) for the 2020 2021. <bold>Methods</bold> Data DALYs, mortality were derived from Global Burden Disease Study 2019. The data carefully estimated presented in both numerical values age-standardized...