A5073261457- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Fish Biology and Ecology Studies
- Microplastics and Plastic Pollution
- Parasite Biology and Host Interactions
- biodegradable polymer synthesis and properties
- SARS-CoV-2 and COVID-19 Research
- Helminth infection and control
- Advanced Photonic Communication Systems
- Optical Network Technologies
- Physiological and biochemical adaptations
- Digital Imaging for Blood Diseases
- Zebrafish Biomedical Research Applications
- Antioxidant Activity and Oxidative Stress
- Nanoparticles: synthesis and applications
- COVID-19 Clinical Research Studies
- Environmental Toxicology and Ecotoxicology
- Pharmaceutical and Antibiotic Environmental Impacts
- Diverse Scientific Research Studies
- Invertebrate Immune Response Mechanisms
- Artificial Intelligence in Healthcare
- Advanced Fiber Laser Technologies
- Photodynamic Therapy Research Studies
- Medical and Biological Ozone Research
- Electrospun Nanofibers in Biomedical Applications
Universidade Estadual Paulista (Unesp)
2021-2024
This study aims to demonstrate the applicability and importance of zebrafish (Danio rerio) model acute chronic inflammatory responses induced by different stimuli: carrageenan phlogogen (nonimmune); infection bacteria (immune); foreign body reaction (chronic inflammation round glass coverslip implantation); xenotransplantation. In addition advantages presenting low breeding cost, high prolificity, transparent embryos, number individuals belonging same spawning genetic similarity that favor...
Zileuton is an inhibitor of the 5-lipoxygenase enzyme that transforms essential fatty acid (EFA) substrates into leukotrienes (LTB4, LTC4, LTD4 and LTE4), but little known about use this drug in teleost fish. Therefore, objective study was to evaluate clinical safety treatments with 2,25 mg 4,50 zileuton/Kg -1 (bodyweight), administered orally diet, through biochemical hematological analysis during acute inflammatory reaction Nile tilapia ( Oreochromis niloticus ), induced by Aeromonas...
Although the exact mechanism of pathogenesis coronavirus SARS-CoV-2 (COVID-19) is not fully understood, oxidative stress and release pro-inflammatory cytokines have been highlighted as playing a vital role in disease. In this sense, alternative treatments are needed to reduce level inflammation caused by COVID-19. Therefore, study aimed investigate potential effect red photobiomodulation (PBM) an attractive therapy downregulate cytokine storm COVID-19 zebrafish model. RT-qPCR analyses...
Seeking to understand the defense mechanisms of tilapia assist in sanitary management fish farms, this study aimed evaluate clinical safety Nile (Oreochromis niloticus) submitted oral treatment with 500μg zafirlukast/Kg body weight during chronic inflammation, through implantation round glass coverslips subcutaneous tissue. For study, 63 male tilapiawere randomly distributed 9 aquariums compose following treatments: Control inflammatory stimulus without treatment; CT – Conventional PT...
This study aimed to evaluate the clinical safety of doxycycline treatment (Sandoz Pharmacetical Industry from Brazil Ltd.), administered orally incorporated into feed Nile tilapia, Oreochromis niloticus. For this purpose, 75 tilapia (± 300g) same spawning were randomly distributed in 15 tanks (n=5), containing 100 L water each, supplied with running free chlorine, establish following treatments: T0 (Control - not treated doxycycline); T1, T2, T3 and T4 (treated 10, 20, 40 80mg doxycycline/kg...
Introdução: A necessidade de substituir antibióticos em rações aquáticas está aumentando, e substâncias alternativas seguras são agora incentivadas para atividades aquicultura sustentável. curcumina é considerada um aditivo alimentar multifuncional com potencial promotor crescimento imunoestimulante. Dado seu potencial, crucial aprofundar os estudos sobre a segurança clínica como peixes, garantindo que uso contribua forma segura eficaz sustentabilidade da aquicultura. Objetivos: avaliar do...
Introdução: A aquicultura é vital para a segurança alimentar global, mas intensificação do cultivo tem aumentado surtos de doenças infecciosas, exigindo o uso antimicrobianos. Devido à limitação medicamentos registrados peixes, novas alternativas estão sendo estudadas. Este estudo investiga clínica uma nova combinação antimicrobianos, sulfametoxazol e trimetoprima (SMZ-TMP), em tilápias, utilizando parâmetros hematológicos bioquímicos. Objetivos: Avaliar da Sulfametoxazol- Trimetoprima...
This study aimed to evaluate the effect of astaxanthin on hematological, biochemical and somatic response Nile tilapia ( Oreochromis niloticus ) orally administered in feed for a period 60 days. For study, 105 (n=35) from same spawn were used, constituting following treatments: Control = animals (not treated with astaxanthin); T100 T200 fish 100 200 mg astaxanthin/kg feed, respectively. There no hematological alterations red blood cells counts, hematocrit, hemoglobin, MCV MCHC. In addition,...
Identifying activation pathways and effector mechanisms of innate immunity in fish has become crucial for the sanitary management intensive farming. However, there is limited knowledge regarding blockade cysteinyl leukotriene receptors (CysLTRs) their effects teleost fish. The present study investigated Zafirlukast, antagonist CysLTR1 receptor, on foreign body inflammatory reaction Nile tilapia (Oreochromis niloticus). 63 male (weighing ± 100g), from same spawning were randomly distributed...
Ivermectin belongs to the group of avermectins, a macrocyclic lactones produced by Streptomyces avermitilis, this drug is widely used in treatment endoparasitoses and ectoparasitosis different species mammals around world. Based on need develop an adequate sanitary management fish farms therapeutic importance lactones, study aimed evaluate clinical safety ivermectin administered orally as part feed for Nile tilapia (O. niloticus). For this, 56 tilapias niloticus), ±100g, were placed 7...
Ivermectin belongs to the group of avermectins, a macrocyclic lactones produced by Streptomyces avermitilis, this drug is widely used in treatment endoparasitoses and ectoparasitosis different species mammals around world. Based on need develop an adequate sanitary management fish farms therapeutic importance lactones, study aimed evaluate clinical safety ivermectin administered orally as part feed for Nile tilapia (O. niloticus). For this, 56 tilapias niloticus), ±100g, were placed 7...
We report on using support vector classifiers (SVCs) to mitigate the residual and fiber-induced nonlinear distortions in a digital coherent optical communication system employing dual-polarization 16-ary quadrature amplitude modulation with data rate of 100 Gbps.Simulation results reveal that SVC can partially tackle effect intra-polarization inter-polarization crosstalk.Simulations also show processing information both polarizations leads improved performance but needs take special care...
The use of Poly (lactic acid) (PLA) as a slow-release vehicle for vaccines has attracted the attention researchers, since its insertion improves uptake them, and reduces side effects or by stimulate recruited defense cells, assisting immunity without need booster vaccine doses. Seeking to develop new strategies administration drugs in aquaculture, we evaluated biocompatibility biodegradation polymeric PLA devices plus vitamin E, implanted through subcutaneous (SC) intraperitoneal (IP) routes...
Lincomycin is a broad-spectrum antimicrobial acting against Gram-positive bacteria, widely used in veterinary medicine. In fish, there are only limited vitro data, thus requiring the design of effective therapeutic protocols for their use aquatic organisms. this context, objective was to evaluate clinical safety lincomycin treatment, administered orally tilapia, through hematological, biochemical and somatic index evaluation. A total 136 tilapia (±100g) were randomly distributed 17 tanks...