Xi-Mei Chen

ORCID: 0009-0004-8883-2086
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About
Contact & Profiles
Research Areas
  • Liver Disease Diagnosis and Treatment
  • Helicobacter pylori-related gastroenterology studies
  • Angiogenesis and VEGF in Cancer
  • Pancreatic and Hepatic Oncology Research
  • Immune Response and Inflammation
  • Peroxisome Proliferator-Activated Receptors
  • Eosinophilic Esophagitis
  • Lymphatic System and Diseases
  • Gastroesophageal reflux and treatments
  • Lipid metabolism and disorders
  • Cancer, Lipids, and Metabolism
  • Biofuel production and bioconversion
  • Diet, Metabolism, and Disease
  • Chromosomal and Genetic Variations
  • Immune Cell Function and Interaction
  • Cancer Cells and Metastasis
  • Estrogen and related hormone effects
  • Cancer, Hypoxia, and Metabolism
  • Viral gastroenteritis research and epidemiology
  • Epigenetics and DNA Methylation
  • Gastric Cancer Management and Outcomes
  • Cancer-related molecular mechanisms research
  • Liver physiology and pathology
  • Inflammatory Bowel Disease
  • Advanced Cellulose Research Studies

Chongqing Technology and Business University
2024

Dalian Medical University
2019

First Affiliated Hospital of Zhengzhou University
2017

Guangdong University of Technology
2016-2017

Tongji Hospital
2007-2014

Tongji University
2007-2014

University of Macau
2011

University of Manitoba
2009

Kaiping Central Hospital
2009

Shanghai Institute of Hematology
2008

To investigate the efficacy and safety of n-3 polyunsaturated fatty acids (PUFA) from seal oils for patients with nonalcoholic liver disease (NAFLD) associated hyperlipidemia.One hundred forty-four NAFLD hyperlipidemia were included in 24-wk, randomized, controlled trial. The randomized into two groups. Group A (n=72) received recommended diet 2 g PUFA oils, three times a day. B placebo, Primary endpoints assessed by symptom scores, alanine aminotransferase (ALT) serum lipid levels after 8,...

10.3748/wjg.14.6395 article EN cc-by-nc World Journal of Gastroenterology 2008-01-01

Patients with gastric cancer in China have worse outcome and poorer prognosis. Tumor-induced lymphangiogenesis plays a crucial role metastasis tumor progression. The intratumoral peritumoral lymphatics were supposed to different biological effects. Three major growth factors, vascular endothelial factor- (VEGF)-A, VEGF-C VEGF-D, are involved the activation process via their receptors (VEGFRs). purpose of current study is investigate significant difference between lymphatic vessel density...

10.1186/1471-2407-10-299 article EN cc-by BMC Cancer 2010-06-17

Cancer cell invasion and metastasis are the most important adverse prognostic factors for pancreatic cancer. Identification of biomarkers associated with outcome cancer may provide new approaches targets anticancer therapy. The aim this study is to examine relationship between expression RhoT1, Smad4 p16 survival in patients analysis showed that high cytoplasmic levels tissues had significantly negative correlation lymph node (LNM) (P = 0.017, P 0.032, 0.042, respectively). However, no...

10.1371/journal.pone.0042234 article EN cc-by PLoS ONE 2012-07-31

year, the iMELD still had highest AUC (0.783), difference between and MELD was statistically significant (P < 0.05).Survival curves showed that three new models were all clearly discriminated patients who survived or died in short-term as well intermediate-term 0.001).CONCLUSION: Three models, changed with serum sodium (MELD-Na, iMELD, MESO) can exactly predict prognosis of decompensated cirrhosis for short intermediate period, may enhance prognostic accuracy MELD.The is better model outcome...

10.3748/wjg.14.6546 article EN cc-by-nc World Journal of Gastroenterology 2008-01-01

AIM:To evaluate the possible role of Tribble 3 (TRB3) in a rat model non-alcoholic fatty liver disease (NAFLD) and its signal transduction mechanism.METHODS: T h i r ty S p ra g u e -D w l y t s randomized into three groups: normal control group, group A (fed on highfat diet for 8 wk) B high-fat 16 wk).To determine degree hepatic steatosis rats each livers were stained with hematoxylin eosin, evaluated; realtime fluorescent quantitative reverse transcriptasepolymerase chain reaction was...

10.3748/wjg.15.2329 article EN cc-by-nc World Journal of Gastroenterology 2009-01-01

目的:探讨IL-1B.1473基因与萎缩性胃炎的相关性. 方法:选择上海同济医院经病理确诊的慢性萎缩性胃炎和慢性浅表性胃炎患者各100例,收集其外周血标本和流行病学调查资料,抽提标本DNA,以多重SNaPshot技术检测IL—IB.1473单核苷酸多态性.结果:IL-1B-1473基因在萎缩组和非萎缩组的基因型分布频率未见显著性差异.IL-1B.1473基因与慢性萎缩性胃炎的萎缩程度无显著关联,携带.1473G/G的个体与携带.1473C/C者比较,其发生萎缩的危险性增加32%(OR=1.32,95%CI:0.55.3.16),但未达到统计学显著性水平. 结论:IL-1B-1473基因具有萎缩性胃炎易感性.

10.11569/wcjd.v17.i12.1202 article ZH-CN cc-by-nc Shijie huaren xiaohua zazhi 2009-01-01
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