- Lysosomal Storage Disorders Research
- RNA regulation and disease
- Hemophilia Treatment and Research
- Alzheimer's disease research and treatments
- Amyotrophic Lateral Sclerosis Research
- Pancreatic and Hepatic Oncology Research
- Studies on Chitinases and Chitosanases
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Glycogen Storage Diseases and Myoclonus
- Eosinophilic Disorders and Syndromes
- Cancer Research and Treatments
- MicroRNA in disease regulation
- Ovarian cancer diagnosis and treatment
- Carbohydrate Chemistry and Synthesis
Takeda (United States)
2024
Takeda (Japan)
2024
Zhejiang Cancer Hospital
2023
University of Chinese Academy of Sciences
2023
Second Affiliated Hospital of Zhengzhou University
2018
National Taiwan University Hospital
2018
Peking Union Medical College Hospital
2017
Chinese Academy of Medical Sciences & Peking Union Medical College
2017
Southern Medical University
2015
Nanfang Hospital
2015
Abstract Fabry disease, an X-linked lysosomal storage disorder caused by galactosidase alpha (GLA) gene mutations, exhibits diverse clinical manifestations, and poses significant diagnostic challenges. Early diagnosis treatment are crucial for improved patient outcomes, pressing the need reliable biomarkers. In this study, we aimed to identify miRNA candidates as potential biomarkers disease using KingFisher™ automated isolation method NanoString nCounter® detection assay. Clinical serum...
To explore the effects of melatonin (MT) on expressions β-amyloid protein (β-AP) and S100β in rats with senile dementia.A total 36 Sprague-Dawley were randomly divided into Sham group, Model group MT 12 each group. Senile dementia models established except After modeling, given tail vein injection 0.9% sodium chloride once per day. Rats Materials collected at 40 d after intervention. Hematoxylin-Eosin (HE) staining was adopted to observe histomorphology hippocampal area, Western blotting...
Fabry disease, an X-linked lysosomal storage disorder caused by galactosidase α (GLA) gene mutations, exhibits diverse clinical manifestations, and poses significant diagnostic challenges. Early diagnosis treatment are crucial for improved patient outcomes, pressing the need reliable biomarkers. In this study, we aimed to identify miRNA candidates as potential biomarkers disease using KingFisher™ automated isolation method NanoString nCounter® detection assay. Clinical serum samples were...
Objective: The study aimed to investigate whether sample sizes of F-wave differed according different nerves, parameters, and amyotrophic lateral sclerosis(ALS) patients or healthy subjects. Methods: F-waves in the median, ulnar, tibial, deep peroneal nerves 55 sclerosis (ALS) 52 subjects were studied assess effect size on accuracy measurements following parameters: minimum latency, maximum mean persistence, chronodispersion, amplitude. A hundred stimuli used study. values obtained from 100...