Shengyong Wu

ORCID: 0000-0003-2916-5143
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About
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Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pancreatitis Pathology and Treatment
  • Peptidase Inhibition and Analysis
  • Tracheal and airway disorders
  • Cancer Genomics and Diagnostics
  • Neuroendocrine Tumor Research Advances
  • Cardiac Imaging and Diagnostics
  • Esophageal and GI Pathology
  • Cardiac Structural Anomalies and Repair
  • Glioma Diagnosis and Treatment
  • Cancer Cells and Metastasis
  • Protease and Inhibitor Mechanisms
  • Cardiovascular Disease and Adiposity
  • Head and Neck Anomalies
  • Nutrition and Health in Aging
  • Trauma and Emergency Care Studies
  • Cardiac Health and Mental Health
  • Epilepsy research and treatment
  • Cardiac Fibrosis and Remodeling
  • Burn Injury Management and Outcomes
  • Cardiovascular Issues in Pregnancy
  • Esophageal Cancer Research and Treatment
  • Amyotrophic Lateral Sclerosis Research
  • Photodynamic Therapy Research Studies

Second Military Medical University
2021-2024

Changhai Hospital
2021-2022

Government of Jilin Province
2021

The University of Texas MD Anderson Cancer Center
2014

Tianjin Medical University General Hospital
2013

Tianjin Medical University
2013

The First People's Hospital of Tianmen
2013

St. Jude Children's Research Hospital
2010

Objectives To investigate and compare the associated factors of depression, anxiety, other psychological differences between patients with Corona Virus Disease 2019 quarantined in square cabin hospitals (SCH) isolation wards (IW) China. Methods Cluster sampling method was performed during Shanghai’s Two-Month Lockdown 2022. Hospital Anxiety Depression Scale subscale (HADS-D), 7-tiem Generalized Disorder (GAD-7), Pittsburgh sleep quality index (PSQI), Perceived Social Support (PSSS) were used...

10.3389/fpsyt.2024.1339774 article EN cc-by Frontiers in Psychiatry 2024-02-05

The adverse effects of proton pump inhibitors (PPIs) on pneumonia have been well reported. However, the relationship between use PPIs and outcomes coronavirus disease 2019 (COVID-19) is currently inconclusive. In this study, we aimed to explore in-hospital mortality among patients who were laboratory-confirmed SARS-CoV-2.Data was derived from 2 hospitals which both first batch SARS-CoV-2 specialist with four types sensitivity analyses. This cohort included 4634 older than 18 years...

10.7189/jogh.12.05005 article EN cc-by Journal of Global Health 2022-02-16

Objective: This study aimed to explore the association between base excess (BE) and risk of 30-day mortality among patients with acute kidney injury (AKI) in intensive care unit (ICU). Methods: retrospective included AKI from Medical Information Mart for Intensive Care (MIMIC)-IV database. We used a multivariate Cox proportional-hazards model obtain hazard ratio (HR) AKI. Furthermore, we utilized proportional-hazard restricted cubic splines (RCS) potential non-linear associations. Results:...

10.3389/fmed.2021.779627 article EN cc-by Frontiers in Medicine 2021-12-02

Background: Notwithstanding that significant medical progress has been achieved in recent years, the optimal nutritional support method following pancreaticoduodenectomy (PD) remains uncertain. This study compared safety and feasibility of early oral feeding (EOF) with nasojejunal enteral nutrition (NJEEN) after PD. Methods: A retrospective cohort was conducted on 428 consecutive patients who underwent PD between August 2018 December 2020. During first phase, routine postoperative strategy...

10.1097/js9.0000000000000786 article EN cc-by-nc-nd International Journal of Surgery 2023-09-25

Stanford type A aortic dissection (T(A)AD) is one of the most dangerous cardiovascular diseases and morbid obesity associated with prognosis many diseases. The aim this study to investigate impact on in-hospital mortality, total hospital costs discover prevalence among inpatients T(A)AD.Patients a primary diagnosis T(A)AD were identified from National Inpatient Sample database (NIS) 2008 2017. These patients categorized into non-obesity, obesity. Multivariable regression models utilized...

10.1186/s13019-022-02080-6 article EN cc-by Journal of Cardiothoracic Surgery 2023-01-10

The relationship between epilepsy and risk of acute myocardial infarction (AMI) is not fully understood. Evidence from the Stockholm Heart Study indicates that AMI increased in people with epilepsy. This study aims to analyze temporal trends prevalence, adverse clinical outcomes, factors patients (PWE).

10.3389/fneur.2024.1378682 article EN cc-by Frontiers in Neurology 2024-08-05

We present a rare case of concurrent medullary thyroid cancer (MTC) and relapse Graves' disease (GD).A 26-year-old Chinese female suffered from GD for 1 year.Physical examination demonstrated mildly diffuse goiter with palpable 1.0 cm nodule in the right lobe exophthalmos.Before hemithyroidectomy, calcitonin was elevated thyroglobulin normal.After surgery, histopathological fi ndings proved coexistence MTC GD.16 months later, relapsed radioactive iodine 131 therapy given.Meanwhile,...

10.4149/bll_2013_114 article EN Bratislavské lekárske listy/Bratislava medical journal 2013-01-01

Abstract Early diagnosis of gastrointestinal malignancies in patients with acute coronary syndrome (ACS) is often delayed. The present study aims to demonstrate the value [ 68 Ga]Ga‐FAPI‐04 PET imaging ACS suspected malignancies. Twelve were enrolled, including ST‐elevation myocardial infarction (STEMI) ( n = 5), non‐ST‐elevation (NSTEMI) and unstable angina (UA) 2). All underwent angiography (CAG) PET/MR or PET/CT within 1 week. five STEMI NSTEMI had high uptake injured myocardium compared...

10.1002/viw.20230018 article EN cc-by View 2023-07-27

To construct a novel tumor-node-morphology (TNMor) staging system derived from natural language processing (NLP) of pathology reports to predict outcomes pancreatic ductal adenocarcinoma.This retrospective study with 1657 participants was based on large referral center and The Cancer Genome Atlas Program (TCGA) dataset. In the training cohort, NLP used extract screen prognostic predictors develop TNMor system, which further evaluated tumor-node-metastasis (TNM) in internal external...

10.1097/js9.0000000000000648 article EN cc-by-nc-nd International Journal of Surgery 2023-08-14

Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant tumor and insensitive to radiotherapy chemotherapy, as it correlated with its complex microenvironment (TME). A comprehensive description of PDAC's immune at the pathological level has not been reported, thus limiting treatment. Previous studies have shown that large-section histopathology (LSH) can reveal complete structure margin on single slice effectively reflect intratumoral heterogeneity. LSH, opposed classic small-section...

10.3389/fonc.2021.694933 article EN cc-by Frontiers in Oncology 2021-07-12

Aim To investigate the incidence and outcomes of acute high-risk chest pain diseases, including myocardial infarction (AMI), aortic dissection (AD), pulmonary embolism (PE) during pregnancy puerperium. Methods The National Inpatient Sample was queried to identify pregnancy-related hospitalizations from January 1, 2008 December 31, 2017. Temporal trends in mortality AMI, AD PE were extracted. Results Among 41,174,101 hospitalizations, diseases diagnosed 40,285 (0.098%). increased...

10.3389/fcvm.2022.968964 article EN cc-by Frontiers in Cardiovascular Medicine 2022-08-11

Glioblastoma, with aberrant activation of growth factor signaling pathways, represents a compelling disease for kinase inhibitor therapy. Despite the evidence defining PI3K network as high quality target, regulatory feedback loops well cross-talk other networks make understanding and targeting challenging task. As result selective pressure by PI3 inhibitors, glioblastoma: 1) up-regulates compensatory survival pathways 2) utilizes complimentary predominant mechanism escape from anti-PI3K...

10.1093/neuonc/nou252.8 article EN Neuro-Oncology 2014-11-01
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