A5101402499- Cardiac electrophysiology and arrhythmias
- Parasite Biology and Host Interactions
- Soil and Water Nutrient Dynamics
- Soil Carbon and Nitrogen Dynamics
- Parasitic Infections and Diagnostics
- Composting and Vermicomposting Techniques
- Neuroscience and Neural Engineering
- Helminth infection and control
- Supercapacitor Materials and Fabrication
- Ion channel regulation and function
- Peatlands and Wetlands Ecology
- Coastal wetland ecosystem dynamics
- Microbial Community Ecology and Physiology
- Parasitic infections in humans and animals
- Pharmaceutical and Antibiotic Environmental Impacts
- Constructed Wetlands for Wastewater Treatment
- Advanced battery technologies research
- Photodynamic Therapy Research Studies
- Parasites and Host Interactions
- Advancements in Battery Materials
- Cardiac Fibrosis and Remodeling
- HIV Research and Treatment
- Recycling and Waste Management Techniques
- Advanced Memory and Neural Computing
- Air Quality and Health Impacts
Southeast University
2024-2025
First Affiliated Hospital of Jinan University
2022-2025
Union Hospital
2025
Huazhong University of Science and Technology
2025
Sun Yat-sen University
2021-2025
Guangzhou Medical University
2025
Chinese Academy of Sciences
2019-2024
Northeast Institute of Geography and Agroecology
2019-2024
Sichuan University
2021-2024
West China Second University Hospital of Sichuan University
2021-2024
Layered double hydroxides (LDHs) have come to the foreground recently, considering their unique layered structure and short ion channels when they act as electrode materials for supercapacitors (SCs). However, due poor rate cycle performance, are not highly sought after in market. Therefore, a flower-like hierarchical NiCo-LDH@C nanostructure with flake NiCo-LDH anchored on carbon skeleton has emerged here, which is constructed by calcination hydrothermal reaction applying ZIF-67 precursor....
Recent in vitro cardiac safety studies demonstrate the ability of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) to detect electrophysiologic effects drugs. However, variability contributed by unique approaches, procedures, cell lines, and reagents across laboratories makes comparisons results difficult, leading uncertainty about role hiPSC-CMs defining proarrhythmic risk drug discovery regulatory submissions. A blinded pilot study was conducted evaluate 8...
Available information on the microbial mechanisms associated with heavy metal (HM) passivation during co-composting amended phosphate rock (PR) remains limited. Thus, this study investigated dynamic changes in bacterial communities and HM-fractions (Zn, Cu, Cd, Cr Pb) swine manure composting maize straw, ascertained influence HM-passivation. The results demonstrated that addition of PR improved HM-passivation, especially for Zn their bioavailability factors (BFs) reduced by 247.41 176.25%,...
We conducted a large-scale whole-brain morphometry study by analyzing 3.7 peta-voxels of mouse brain images at the single-cell resolution, producing one largest multi-morphometry databases mammalian brains to date. registered 204 three major imaging modalities Allen Common Coordinate Framework (CCF) atlas, annotated 182,497 neuronal cell bodies, modeled 15,441 dendritic microenvironments, characterized full morphology 1876 neurons along with their axonal motifs, and detected 2.63 million...
The vascular endothelial growth factor A (VEGF-A)/VEGF receptor 2 (VEGFR-2) signaling pathway is pivotal in regulating angiogenesis. We have synthesized a linear peptide-based VEGFR-2-targeted positron emission tomography (PET) tracer, but its target affinity and vivo stability need further improvement. In this study, we developed two novel 64Cu-labeled PET dimer tracer [64Cu]VEGF2215 [64Cu]VEGF2216 modified with pegylated branched linker, respectively, to optimize pharmacokinetic properties...
A new integrated tunable microfluidic particle synthesis and shape population analysis workflow allows us to study the immunological readouts for even highly complex shaped nanoparticles. Using this approach, we demonstrate that some gold nanoparticles, when injected parenterally, are taken up by axillary brachial lymph nodes. We then show specific nanoparticle shapes influence primary structure of T cell receptor, inducing changes in hypervariable complementary-determining regions (CDRs)...
Neuron morphology and sub-neuronal patterns offer vital insights into cell typing the structural organization of brain networks. The community-collaborative BRAIN Initiative Cell Census Network (BICCN) project has yielded a vast amount whole-brain imaging data. However, reconstructing multi-scale neuron morphometry at scale requires not only integration diverse hardware devices, tools, algorithms but also dedicated production workflow. To address these challenges, we developed cloud-based,...
Myocardial infarction (MI) leads to heart failure (HF) and premature death. The respective roles of myocyte death depressed contractility in the induction HF after MI have not been clearly defined are focus this study.We developed a mouse model which we could prevent used it test idea that preventing depression Ca(2+)-handling defects avert post-MI cardiac pump dysfunction.MI was produced mice with inducible, cardiac-specific expression β2a subunit L-type Ca(2+) channel. Myocyte function...
Abstract Throughout history, the development of artificial intelligence, especially neural networks, has been continuously influenced by a deeper understanding brain. This influence includes neocognitron, considered precursor to convolutional networks. The emerging field NeuroAI posits that leveraging neuroscience knowledge could significantly advance AI imbuing networks with enhanced capabilities. Unlike human brain, which features variety morphologically and functionally distinct neurons,...