Suzhen Guan

ORCID: 0009-0004-9626-8884
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About
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Research Areas
  • Stress Responses and Cortisol
  • Birth, Development, and Health
  • Maternal Mental Health During Pregnancy and Postpartum
  • Workplace Health and Well-being
  • Gut microbiota and health
  • Sleep and related disorders
  • Neuroendocrine regulation and behavior
  • Employment and Welfare Studies
  • Resilience and Mental Health
  • Health, psychology, and well-being
  • Tryptophan and brain disorders
  • Sleep and Wakefulness Research
  • Stress and Burnout Research
  • Healthcare professionals’ stress and burnout
  • Transgenic Plants and Applications
  • Toxin Mechanisms and Immunotoxins
  • Posttraumatic Stress Disorder Research
  • Sleep and Work-Related Fatigue
  • Health and Well-being Studies
  • Obstructive Sleep Apnea Research
  • Intergenerational Family Dynamics and Caregiving
  • Biomarkers in Disease Mechanisms
  • Family Support in Illness
  • Heavy Metal Exposure and Toxicity
  • Heavy metals in environment

Ningxia Medical University
2017-2025

Ningxia Center for Diseases Prevention and Control
2021-2025

Xinjiang Medical University
2014-2020

Nantong University
2016

Job strain is a major concern in view of its effects among civil servants associated with job burnout, mental fatigue and chronic diseases. The objective this study was to assess the level examine effect on resulting A cross-sectional representative sample consisting 5000 conducted from March August 2014. Using structured questionnaire, level, burnout were measured by using Personal Strain Questionnaire (PSQ), Maslach Burnout Inventory (MBI) Multidimensional Fatigue (MFI-20), respectively....

10.3390/ijerph14080872 article EN International Journal of Environmental Research and Public Health 2017-08-03

It is debatable whether or not glucocorticoid receptor (GR) polymorphisms moderate susceptibility to PTSD. Our objective was examine the effects of stressful life events, social support, GR genotypes, and gene-environment interactions on etiology PTSD.Three tag single nucleotide polymorphisms, trauma support were assessed in 460 patients with PTSD 1158 control subjects from a Chinese Han population. Gene-environment analyzed by generalized multifactor dimensionality reduction...

10.1186/s12888-014-0232-9 article EN cc-by BMC Psychiatry 2014-08-11

Abstract Background Prenatal stress can cause neurobiological and behavioral defects in offspring; environmental factors play a crucial role regulating the development of brain behavioral; this study was designed to test verify whether an enriched environment repair learning memory impairment offspring rats induced by prenatal explore its mechanism involving expression insulin-like growth factor-2 (IGF-2) activity-regulated cytoskeletal-associated protein (Arc) hippocampus offspring. Methods...

10.1186/s12199-020-00929-7 article EN cc-by Environmental Health and Preventive Medicine 2021-01-15

Mental health issues, particularly anxiety and depression, are increasingly prevalent among the occupational population. Environmental factors, such as dust exposure, may contribute to worsening of these symptoms. While previous studies have examined association between exposure mental health, moderating effect sleep duration on this link in settings remains under-explored. This study was conducted from July October 2023 at The Fifth People's Hospital Ningxia recruited dust-expose d workers...

10.1186/s12889-025-21520-1 article EN cc-by-nc-nd BMC Public Health 2025-01-29

Sleep disorders are among the most common major problems during pregnancy. Most studies on sleep of pregnant women closely related to adverse birth outcomes. In this study, our aim was develop and validate a predictive model for risk in women. A total 2,467 healthy were enrolled randomly partitioned into training set validation at ratio 7:3. During variable selection stage, Pearson's chi-square test employed identify variables with p-value below 0.05, which then designated as candidate...

10.1186/s12884-025-07197-9 article EN cc-by-nc-nd BMC Pregnancy and Childbirth 2025-03-06

Environmental metal exposure is associated with elevated triglycerides (TG) and the development of chronic kidney disease (CKD). However, relationship between glomerular filtration rate (GFR) remains uncertain, mediating effect TG two unclear.This study measured concentrations 14 metals in urine samples from 3752 elderly people community. The most relevant were screened by least absolute shrinkage selection operator (LASSO) regression. combined to multiple abnormal estimated (eGFR) was...

10.1016/j.ecoenv.2023.114966 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2023-05-12

<h3>Objectives</h3> The aim of this study was to assess the risk cataract following protracted low doses radiation exposure among industry radiographers and comparison groups unexposed workers. <h3>Methods</h3> A cohort 1401 1878 workers in China followed up for 12 years. lens were based on individual monitoring. Presence assessed clinically photographs using Lens Opacities Classification System III. Radiation dose–response analyses performed incidence by Poisson regression, adjusting...

10.1136/oemed-2014-102772 article EN Occupational and Environmental Medicine 2015-07-10

This study aims to investigate the relationships of personality and social support with posttraumatic stress disorder (PTSD) after traffic accidents. The 90 Symptom Checklist (SCL-90) Eysenck Personality Questionnaire (EPQ) were completed 1 week trauma. Checklist-Civilian Version (PCL-C) was surveyed 3 months discharge. PCL-C score 38 used as cutoff point. older age lower education significantly increased PTSD incidence. SCL-90 positively correlated symptom score. psychoticism (P) (0.230)...

10.1097/md.0000000000007815 article EN cc-by-nc Medicine 2017-08-01

Stress during pregnancy is not only detrimental to a woman's own physical and mental health, but can also cause changes in the intrauterine environment even have an impact on later growth development, this study was designed understand of gut microbiota maternal offspring caused by prenatal chronic stress, explore regulatory effect LBP microbiota, then improve emotional damage stress offspring. A rat model made used intervene gavage. Fresh feces were collected, concentration microbial...

10.1016/j.biopha.2021.112087 article EN Biomedicine & Pharmacotherapy 2021-08-30

The present study investigated the association between resilience, stigma, life satisfaction and intention to receive a COVID-19 vaccination among Chinese HCWs. It also explored mediating role of stigma on resilience vaccination.An anonymous cross-sectional survey.1733 HCWs from five hospitals in four provinces mainland China completed online survey October November 2020.Among HCWs, rate was 73.1%. Results structural equation modelling showed that associated both directly, indirectly with...

10.1111/jan.15143 article EN Journal of Advanced Nursing 2022-02-23

The present study aims to investigate psychological stress and its determinants in Xinjiang field oil workers. Specifically, we aim elucidate the mechanisms underlying by comprehensively quantitatively evaluating processes involved stress, factors which influence it, their relationship. participants were 1200 workers who had been service for at least 1 year. A structural equation model based on data from symptom checklist, social support research scale, personality questionnaire,...

10.1097/md.0000000000010323 article EN cc-by-nc Medicine 2018-04-01

The present study compared the level of occupational strain and work ability among Han, Hui, Uygur, Kazakh teachers, explored ethnic differences based on associations psychosocial factors at work, strain, ability. A cross-sectional survey was conducted 2,941 teachers in primary secondary schools Xinjiang Province, China. Psychosocial factors, were measured using Occupation Stress Inventory—Revised Edition (OSI-R) Work Ability Index. Han Hui experienced reduced with Uygur this finding caused,...

10.1080/19338244.2014.956859 article EN Archives of Environmental & Occupational Health 2014-08-26

Background Chronic long-term stress is associated with a range of disorders, including depression and variety other chronic illnesses. It well known that maternal exposure to psychosocial during pregnancy significantly increases the likelihood adverse outcomes. The gut microbiota has been popular topic, it key mediator gut-brain axis plays an important role in human health; changes have related stress-induced health impairment, however, relationship between negative emotions abnormal its...

10.7717/peerj.15113 article EN cc-by PeerJ 2023-04-17
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