Chen Zhang

ORCID: 0000-0002-8771-561X
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About
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Research Areas
  • HIV, Drug Use, Sexual Risk
  • HIV/AIDS Research and Interventions
  • Sex work and related issues
  • Adolescent Sexual and Reproductive Health
  • Sexuality, Behavior, and Technology
  • HIV Research and Treatment
  • Corporate Taxation and Avoidance
  • Homelessness and Social Issues
  • LGBTQ Health, Identity, and Policy
  • HIV/AIDS drug development and treatment
  • Hepatitis C virus research
  • Healthcare professionals’ stress and burnout
  • Viral gastroenteritis research and epidemiology
  • Taxation and Compliance Studies
  • Intimate Partner and Family Violence
  • Hepatitis B Virus Studies
  • Genital Health and Disease
  • Technology Adoption and User Behaviour
  • Noise Effects and Management
  • Workplace Health and Well-being
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Health, psychology, and well-being
  • Acute Ischemic Stroke Management
  • Urologic and reproductive health conditions
  • Family Support in Illness

University of Rochester Medical Center
2018-2025

Southeast University
2025

Renmin University of China
2022-2025

Zhongda Hospital Southeast University
2022-2025

Obstetrics and Gynecology Hospital of Fudan University
2021-2024

Zhengzhou University of Aeronautics
2024

University of Rochester
2016-2024

Army Medical University
2024

Xinqiao Hospital
2024

Southwest University
2024

On January 20, 2020, a new coronavirus epidemic with human-to-human transmission was officially declared by the Chinese government, which caused significant public panic in China. In light of disease 2019 outbreak, pregnant women may be particularly vulnerable and special need for preventive mental health strategies. Thus far, no reports exist to investigate response outbreak.This study aimed examine impact outbreak on prevalence depressive anxiety symptoms corresponding risk factors among...

10.1016/j.ajog.2020.05.009 article EN cc-by-nc-nd American Journal of Obstetrics and Gynecology 2020-05-11

Inbound tourist arrivals into China have been declining in recent years, possibly response to increasing levels of urban air pollution. To examine Westerners' contemporary views on as a travel destination, with particular focus pollution, this research surveyed 600 US and Australian residents. An online panel survey collected data cognitive affective destination image, risk perceptions, intention visit key demographic variables. The findings show that, while China's image attributes were...

10.1080/09669582.2016.1177067 article EN Journal of Sustainable Tourism 2016-05-20

The incidence of cervical cancer continues to rise in underdeveloped regions due low human papillomavirus (HPV) vaccination rates and inadequate screening systems. To achieve convenient, rapid, accurate detection HPV, we developed a three-wire lateral flow strip assay system based on dual-OR logic gates for rapid simultaneous HPV subtypes 16 18 single test. combines three-branch-catalytic hairpin assembly (TCHA)-mediated signal amplification with simple OR gate-based output improve while...

10.1021/acs.analchem.4c05778 article EN Analytical Chemistry 2025-01-29

Hepatitis C virus (HCV) chronically infects approximately 170 million people worldwide, with an increased risk of developing cirrhosis and hepatocellular carcinoma. The study HCV replication pathogenesis has been hampered by the lack efficient stable cell culture system small-animal models infection propagation. In effort to develop a robust system, we constructed human hepatoma lines that contain chromosomally integrated genotype 2a cDNA constitutively produce infectious virus....

10.1128/jvi.79.22.13963-13973.2005 article EN Journal of Virology 2005-10-27

This paper presents our efforts to democratize ChatGPT across language. We release a large language model "Phoenix", achieving competitive performance among open-source English and Chinese models while excelling in languages with limited resources (covering both Latin non-Latin languages). believe this work will be beneficial make more accessible, especially countries where people cannot use due restrictions from OpenAI or local goverments. Our data, code, are available at...

10.48550/arxiv.2304.10453 preprint EN cc-by arXiv (Cornell University) 2023-01-01

Background Patients with cancer and their families often experience significant distress deterioration in quality of life. Psychosocial interventions were used to address patients’ families’ psychosocial needs. Digital technology is increasingly being deliver patients families. Objective A systematic review meta-analysis conducted the characteristics effectiveness digital health on outcomes adult family members. Methods Databases (PubMed, Cochrane Library, Web Science, Embase, CINAHL,...

10.2196/46116 article EN cc-by JMIR Cancer 2024-02-05

Recreational drug use (RDU) may result in sexual disinhibition and higher risk for HIV other sexually transmitted infections (STIs) among men who have sex with (MSM) China. We assessed whether RDU was associated HIV, syphilis, herpes simplex virus type 2 (HSV-2) within the context of multiple partnerships unprotected sex. conducted a cross-sectional study sexually-active MSM six Chinese cities (Kunming, Jinan, Changsha, Zhengzhou, Nanjing, Shanghai) 2012–2013. interviewed participants...

10.1186/s12879-014-0642-9 article EN cc-by BMC Infectious Diseases 2014-12-01

Background Despite recognized vulnerability of female sex workers (FSW), most data on this population are focused their HIV and STI prevalence; studies experience partner violence psychosocial distress limited, especially FSW in China. Methods Findings A cross-sectional survey was administered among 1,022 recruited from 9 different types commercial venues Southwest Partner scales were adapted WHO's Women's Health Domestic Violence scale measured by five indicators, including alcohol...

10.1371/journal.pone.0062290 article EN cc-by PLoS ONE 2013-04-23

Abstract Background Suboptimal adherence to HIV antiretroviral therapy (ART) and concomitant lack of viral control can have severe consequences for health onward transmission among persons living with HIV. Little is known about the barriers facilitators optimal ART heterosexual HIV-positive men. Methods Structural equation modeling (SEM) was performed test a theory-derived model using data from cross-sectional sample 317 self-identified men residing in New York City. We assessed conceptual...

10.1186/s12981-019-0248-9 article EN cc-by AIDS Research and Therapy 2019-11-09

Environmental cadmium (Cd) exposure can cause several pulmonary diseases. Epithelial-mesenchymal transition (EMT) involved in the process of chronic obstructive disease (COPD). However, association between environmental Cd and EMT was unclear COPD patients. This study aimed to analyze associations among circulatory Cd, based on case-control study. Four hundred patients 400 control subjects were recruited. Circulatory detected using atomic adsorption spectrometer. MicroRNA-30 (miR-30)...

10.1016/j.ecoenv.2021.112164 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2021-03-20

Abstract Background The World Health Organization urged governments to prioritize the health and work well-being of nursing staff by promoting a positive working environment. A safe healthy physical psychosocial environment is basic human right for nurses. Job crafting necessary skill when facing challenging conditions. Objectives This cross-sectional correlational research based on Demands-Resources Model aimed explore correlation between among nurses in intensive care unit (ICU) determine...

10.1186/s12912-024-02041-5 article EN cc-by BMC Nursing 2024-06-03

Pre-exposure prophylaxis (PrEP) is an effective strategy in reducing HIV transmission, yet its uptake remains suboptimal. Health care providers play a vital role facilitating PrEP access and care. This qualitative study explores health providers' perspectives on the oral continuum for adults, emphasizing barriers, facilitators, missed opportunities implementation. Drawing interviews with 18 primary New York State, our research investigates multi-level factors influencing awareness,...

10.1089/apc.2024.0241 article EN AIDS Patient Care and STDs 2025-01-28

Background: Many studies have explored the relationship between education and postpartum depression (PPD), with inconsistent results. Our study is to identify which education‐related factors (education attainment, qualifications, cognitive performance) played predominant role in PPD using Mendelian randomization (MR) analysis. Then, we that may mediate effect of on PPD. Method: We performed two‐sample multivariable (MVMR) assess independent impact Based literature review, three mediating...

10.1155/da/8835118 article EN cc-by Depression and Anxiety 2025-01-01

<sec> <title>BACKGROUND</title> HIV pre-exposure prophylaxis (PrEP) is a proven strategy for preventing transmission, yet Black cisgender women remain underrepresented among PrEP users despite their elevated risk. Barriers such as stigma, mistrust, logistical challenges, and limited awareness hinder uptake in this population. Artificial intelligence (AI)-powered chatbots offer promising solutions by providing personalized, stigma-free, accessible education, but effectiveness context remains...

10.2196/preprints.72536 preprint EN 2025-02-11

ABSTRACT Hepatitis C virus (HCV) nonstructural protein 3 (NS3) possesses multiple enzyme activities. The N-terminal one-third of NS3 primarily functions as a serine protease, while the remaining two-thirds serve helicase and nucleoside triphosphatase. Whether activities are functionally interdependent and/or modulated by other viral NS proteins remains unclear. We performed biochemical studies to examine functional interdependence protease domains modulation NS5B, an RNA-dependent RNA...

10.1128/jvi.79.14.8687-8697.2005 article EN Journal of Virology 2005-07-01
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