A5104617715- Advanced MRI Techniques and Applications
- Advanced NMR Techniques and Applications
- Electron Spin Resonance Studies
- Radiomics and Machine Learning in Medical Imaging
- Lanthanide and Transition Metal Complexes
- Cardiovascular Function and Risk Factors
- Medical Imaging Techniques and Applications
Aarhus University
2024-2025
Assessment of liver function is essential before partial hepatectomy to predict the risk post failure, a severe and life-threatening complication. Traditional methods have focused on expected future remnant (FLR) volume estimation. However, does not always correlate with function. We suggest that metabolism might be better surrogate for than volume. Therefore, we aimed investigate metabolic changes in porcine model portal vein ligation (PVL) using hyperpolarized magnetic resonance imaging...
Purpose: Water freely diffuses across cell membranes, making it suitable for measuring absolute tissue perfusion. In this study, we introduce an imaging method conducting coronary artery angiography and quantifying myocardial perfusion the entire heart using hyperpolarized water. Methods: 1H was dissolution dynamic nuclear polarization (dDNP) with UV-generated radicals. Submillimeter resolution images were acquired as 2D projections a spoiled GRE (SPGRE) sequence gated on diastole. Dynamic...
Abstract Chronic kidney disease (CKD) is the tenth biggest killer worldwide and projected to be fifth leading cause of mortality by 2040. CKD an inherently systemic with progressive deterioration kidney, muscle, liver function creating a vicious cycle comorbidity. However, whether energetic deficiency in contributes cardiac dysfunction uraemic cardiomyopathy remains unknown. Using two pre-clinical renal failure models different aetiology rats (4-week 0.75% adenine diet 12-week post-partial...
Motivation: Distinguishing Alzheimer’s Disease form other dementias is becoming increasingly important with the development of amyloid-targeting therapies. This requires extensive clinical and paraclinical work-up, often including structural molecular brain imaging. Goal(s): To compare deuterium metabolic imaging (DMI) routinely used technologies for detection Disease. Approach: We performed a prospective trial 5 healthy age-matched controls compared 10 patients dementia. Results:...