A5017256384- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Viral Infections and Immunology Research
- Hepatitis Viruses Studies and Epidemiology
- Clostridium difficile and Clostridium perfringens research
- Historical Economic and Social Studies
- Salmonella and Campylobacter epidemiology
- Infection Control and Ventilation
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Zoonotic diseases and public health
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Historical and modern epidemiology studies
- COVID-19 and healthcare impacts
- Child and Adolescent Health
- Virus-based gene therapy research
- Animal Disease Management and Epidemiology
- Epigenetics and DNA Methylation
- Animal Virus Infections Studies
- COVID-19 and Mental Health
National Center for Immunization and Respiratory Diseases
2022-2025
Cherokee Nation
2021-2025
Centers for Disease Control and Prevention
2021-2025
Kaiser Permanente Center for Health Research
2022
Oak Ridge Institute for Science and Education
2021-2022
Oak Ridge Associated Universities
2021-2022
Emory University
2017
Excessive inflammation during pregnancy alters homeostatic mechanisms of the developing fetus and has been linked to adverse outcomes. An anti-inflammatory diet could be a promising avenue combat pro-inflammatory state pregnancy, particularly in obese women, but we lack mechanistic data linking this dietary pattern birth In an ethnically diverse cohort 1057 mother-child pairs, estimated relationships between inflammatory potential [measured via energy-adjusted index (E-DII™)] outcomes...
Abstract Background In the United States, norovirus is leading cause of healthcare-associated gastroenteritis outbreaks. To inform prevention efforts, we describe epidemiology outbreaks in long-term care facilities (LTCFs). Methods The Centers for Disease Control and Prevention (CDC) collect epidemiologic laboratory data on from US health departments through National Outbreak Reporting System (NORS) CaliciNet. Reports both systems were merged, nursing homes, assisted living, other LTCFs...
Abstract Knowledge of the epidemiology sporadic acute gastroenteritis (AGE) in United States is limited. During September 2016–September 2017, we surveyed Kaiser Permanente Northwest members Oregon and Washington, USA, to collect data on 30-day prevalence dually defined AGE diarrhea disease related health-seeking behavior; from a subset participants, obtained stool specimen. Using iterative proportional fitting algorithm with raked weights, generated annualized rate estimates. We detected...
Norovirus is the leading cause of acute gastroenteritis (AGE) globally. Few longitudinal studies have assessed norovirus-associated AGE incidence across age groups in community settings Latin America. During April 2015–April 2019, active surveillance for among members all ages was conducted through household visits two to three times per week San Jeronimo, Cusco, Peru. An asymptomatic control selected every fifth case. Stool specimens were collected from cases, members, and they tested...
Abstract Background The National Outbreak Reporting System (NORS) captures data on foodborne, waterborne, and enteric illness outbreaks in the United States. This study describes reported during 11 years of surveillance. Methods We extracted finalized reports from NORS for occurring 2009–2019. Outbreaks were included if caused by an etiology or any patients diarrhea, vomiting, bloody stools, unspecified acute gastroenteritis. Results A total 38 395 met inclusion criteria, increasing 1932...
Abstract During 2009–2018, four adenovirus, 10 astrovirus, 123 rotavirus, and 107 sapovirus gastroenteritis outbreaks were reported to the US National Outbreak Reporting System (annual median 30 outbreaks). Most attributable person-to-person transmission in long-term care facilities, daycares, schools. Investigations of norovirus-negative should include testing for these viruses.
Globally, noroviruses cause infections year-round but have recognized winter seasonality in the Northern Hemisphere and yearly variations incidence. With candidate norovirus vaccines development, understanding temporal geographic trends disease is important to inform potential vaccination strategies evaluate vaccine impact.
OBJECTIVES Acute gastroenteritis (AGE) outbreaks commonly occur in congregate settings, including schools and childcare facilities. These disrupt institutions, causing absences temporary facility closures. This study analyzed the epidemiology of school AGE United States. METHODS We occurring kindergarten to grade 12 facilities reported via National Outbreak Reporting System States from 2009 2019 compared this information 2020 data. case characteristics were using Kruskal-Wallis rank sum...
With recent advances in U.S. clinical trials for norovirus vaccines, it is an opportune time to examine what known about the public receptivity this novel vaccine. From October 2016–September 2017, we surveyed Kaiser Permanente Northwest members Portland, Oregon, ask their level of agreement on a 5-point scale with statements need and willingness get potential vaccine themselves or child analyzed responses according age, occupational status, prior uptake, history diagnoses. The survey...
While costs of norovirus acute gastroenteritis (AGE) to healthcare systems have been estimated, out-of-pocket and indirect incurred by households are not well documented in community settings, particularly developing countries. We conducted active surveillance for AGE two communities Peru: Puerto Maldonado (October 2012–August 2015) San Jeronimo (April 2015–April 2019). Norovirus events with PCR-positive stool specimens were included. Data collected follow-up interviews included...
We characterized common exposures reported by a convenience sample of 202 US patients with coronavirus disease during January-April 2020 and identified factors associated presumed household transmission. The most commonly settings known exposure were households healthcare facilities; among case-patients who had contact confirmed case-patient compared those did not, occupations more common. Among without contact, use public transportation was Within the household, transmission highest from...
Introduction From April 1 to May 31, 2022, Grand Canyon National Park received increased acute gastroenteritis reports. Pooled portable toilet specimens identified norovirus genogroups I and II. We sought determine outbreak transmission contributors individual risk factors while rafting or backpacking in the park. Methods rafters backpackers were surveyed online from June 13–July 8, a Cox proportional hazards model was used identify predictors associated with illness adjusted for potential...
On May 11, 2022, the National Park Service (NPS) Office of Public Health (OPH) and Coconino County Human Services (CCHHS) in Flagstaff, Arizona contacted CDC about a rising number acute gastroenteritis cases among backcountry visitors to Grand Canyon (Grand Canyon). The agencies reviewed illness report forms, assessed infection prevention control (IPC) practices, distributed detailed survey river rafters hikers with permits (backpackers) who visited backcountry. During April 1-June 17, total...
Abstract Background While enteric viruses are highly transmissible, household factors associated with transmission less well documented. We identified individual- and household-level viral acute gastroenteritis (AGE) in a large health care network the United States. Methods Patients presenting AGE were enrolled from April 2014 to September 2016. symptomatic members interviewed, stool specimens collected tested for pathogens. Within household, primary cases those earliest symptom onset...