A5058078791- Zoonotic diseases and public health
- Animal Disease Management and Epidemiology
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- Microbial Natural Products and Biosynthesis
- Metabolomics and Mass Spectrometry Studies
- Viral Infections and Vectors
- Analytical chemistry methods development
- Plant Pathogens and Fungal Diseases
- Viral gastroenteritis research and epidemiology
- Vector-Borne Animal Diseases
- Pesticide and Herbicide Environmental Studies
- Pesticide Residue Analysis and Safety
- Advancements in Semiconductor Devices and Circuit Design
- NMR spectroscopy and applications
- Fungal Biology and Applications
- Viral Infections and Outbreaks Research
- Semiconductor materials and devices
- Insect Resistance and Genetics
- Ion-surface interactions and analysis
- Carbohydrate Chemistry and Synthesis
- Crystallization and Solubility Studies
- Influenza Virus Research Studies
- X-ray Diffraction in Crystallography
- Fungal Plant Pathogen Control
Corteva (United States)
2022-2025
World Health Organization
2025
International Livestock Research Institute
2010-2023
Food and Agriculture Organization of the United Nations
2021-2023
National Veterinary Research Institute
2023
International Federation of Red Cross and Red Crescent Societies
2018
Dow Chemical (United States)
2004-2016
Western Regional Research Center
2009
Edison Agrosciences (United States)
2009
Mycosynthetix (United States)
2006
Abstract Even though raw mass spectrometry data is information rich, the vast majority of underutilized. The ability to interrogate these rich datasets handicapped by limited capability and flexibility existing software. We introduce Mass Spec Query Language (MassQL) that addresses issues enabling an expressive set patterns be queried directly from data. MassQL open-source query language for flexible spectrometer manufacturer-independent mining MS envision flexibility, scalability, ease use...
Field isolates of Phoma macrostoma were obtained from diseased Canada thistle growing in several geographically diverse regions. Bleaching and chlorotic symptoms present on the infected plants. The grown liquid culture found to produce phytotoxic metabolites which also caused bleaching when applied foliarly broadleaf species. Bioassay-directed isolation led discovery macrocidins A B, first representatives a new family cyclic tetramic acids. This chemotype may offer significant potential as...
In outbreak situations involving a novel pathogen timely and coordinated response is crucial. The WHO Scientific Advisory Group for the Origins of Novel Pathogens recently released global framework to guide future scientific investigations into origin emerging pathogens.
Improved retention and distribution of agrochemicals on plant surfaces is an important attribute in the biological activity pesticide. Although plants after spray application can be quantified using traditional analytical techniques including LC or GC, spatial has received little attention. Matrix assisted laser desorption/ionization (MALDI) imaging technology been widely used to determine proteins, peptides metabolites different tissue sections, but its environmental research limited....
Pig rearing is an important income source in the Lao People’s Democratic Republic (PDR), with many smallholder farmers using traditional free-range pig production systems. Despite potentially significant health risks posed by regarding pig-associated zoonoses, information on sociocultural drivers of these zoonoses significantly lacking. This review summarises existing knowledge eight suspected to be endemic Southeast Asia: brucellosis, Q fever (Coxiella burnetii), trichinellosis, hepatitis E...
A new member of the tartrolone series macrodiolides, C (1), was isolated from a Streptomyces species on basis its insecticidal activity. Metacycloprodigiosin (2) and undecylprodigiosin (3) were also same basis. The structure all compounds established by spectroscopic data (NMR, MS, UV).
[reaction: see text] We present two new diffusion-edited NMR experiments, improved DECODES and HETDECODES, that sort the constituents in a mixture by their individual diffusion coefficients. These experiments should allow partial spectral assignment cursory structure elucidation of compounds complex as an aid dereplication known or nuisance compounds.
The ansacarbamitocins are a new family of maytansinoids that unusually substituted with glucose subunit and two carbamate functional groups exhibit modest activity against some agricultural fungal disease organisms. Ansacarbamitocins A-F ( 1- 6) all consist the same macrocyclic core as ansamitocins, variation occurring on unit, while A1 B1 7, 8) additionally lack epoxide group C-4 C-5.
Formulating agrochemical products involves combining several chemical components, including the active ingredient(s), to obtain a final product with desirable efficacy. A formulated incorporates additional components modulate properties that enhance efficacy of active(s) by modifying physical such as viscosity, hydrophobicity, miscibility, and others. In plants, understanding formulation's ability spread on tissues penetrate through outer layer is critical in evaluating product. We have...
A self-aligned complementary GaAs heterostructure FET process has been established for low power, high-speed digital circuits. The devices are fabricated on four-inch MBE epitaxial wafers consisting of AlGaAs/InGaAs epilayers grown LEC substrates. uses twelve lithographic steps including two levels interconnect metal. Typical transconductances 250 mS/mm and 60 achieved 1/spl times/10 /spl mu/m N-channel P-channel devices, respectively. Twenty-three stage unloaded ring oscillators N- P-FETs...
Several Penicillia and one Tricothecium strain produced a new, insecticidally active member of the cycloaspeptide family, with proposed name E (1). The structure, which was determined on basis spectroscopic (NMR, UV, MS) data Marfey amino acid analysis, tyrosine desoxy version A (2). Two synthetic routes to compound 1 were developed: partial synthesis from 2 other total methyl alaninate hydrochloride. Cycloaspeptide E, first this series not contain moiety, is also be reported insecticidal activity.
Cry34Ab1 and Cry35Ab1 proteins, identified from Bacillus thuringiensis strain PS149B1, act together to control corn rootworms. Transgenic lines coexpressing the two proteins were developed protect against rootworm damage. Large quantities of needed conduct studies required for assessing safety this transgenic crop. Because it was technically infeasible obtain sufficient high purity plants, produced using a recombinant Pseudomonas fluorescens (Pf) production system. The both Pf purified...
Cotton plants were genetically modified through the introduction of a synthetic gene that encodes Bacillus thuringiensis insecticidal protoxin referred to as Cry1F(synpro). This is chimeric, full-length δ-endotoxin 130 kDa, comprised core toxin Cry1Fa2 protein and parts nontoxic portions Cry1Ca3 Cry1Ab1 proteins, all which originated from thuringiensis. The Cry1F(synpro) expressed in cotton confers resistance lepidopteran pests. current study was conducted characterize transgenic event...
Three novel cyclodepsipeptides, alveolarides A (1), B (2), and C (3), each possessing the rare 2,3-dihydroxy-4-methyltetradecanoic acid unit a β-phenylalanine amino residue, along with known peptide scopularide were isolated identified from culture broth of Microascus alveolaris strain PF1466. The pure compounds evaluated for biological activity, alveolaride (1) provided strong in vitro activity against plant pathogens Pyricularia oryzae, Zymoseptoria tritici, Ustilago maydis. Moderate was...
Cholecystokinin (CCK) and the different molecular forms of CCK are well established as biomarkers for satiety but accurate analysis has been limited by multiple naturally occurring extensive similarities to gastrin. Changes in levels one form, CCK-8, a eight amino acid peptide CCK, have correlated with responses. Endogenous CCK-8 not characterized Syrian Golden hamsters, an important model study fat uptake digestion. We cloned sequenced hamster identified endogenous from plasma. Hamster is...
An ion of m/z 110.06036 (ion formula [C6H8NO](+); error: 0.32 mDa) was observed in the collision induced dissociation tandem mass spectrometry experiments protonated N-(3-aminophenyl)benzamide, which is a rearrangement product purportedly through nitrogen-oxygen (N-O) exchange. The N-O exchange confirmed by MS/MS spectrum N-(3-aminophenyl)-O (18) -benzamide, where rearranged ion, [C6H8NO ](+) 112 available because presence O . Theoretical calculations using Density Functional Theory (DFT) at...