A5101850962- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- Antimicrobial Peptides and Activities
- Invertebrate Immune Response Mechanisms
- Bone Tissue Engineering Materials
- Biochemical and Structural Characterization
- Polymer Surface Interaction Studies
- Silkworms and Sericulture Research
- Parkinson's Disease Mechanisms and Treatments
- Periodontal Regeneration and Treatments
- Agricultural Innovations and Practices
- Nuclear Receptors and Signaling
- Microplastics and Plastic Pollution
- Phytochemical compounds biological activities
- Hemostasis and retained surgical items
- Immunotherapy and Immune Responses
- Renal and related cancers
- Ginkgo biloba and Cashew Applications
- Chemokine receptors and signaling
- Calpain Protease Function and Regulation
- Cardiomyopathy and Myosin Studies
- Agricultural Engineering and Mechanization
- Antifungal resistance and susceptibility
- Aquaculture disease management and microbiota
- Collagen: Extraction and Characterization
Sichuan University
2022-2025
Ministry of Natural Resources
2025
Fujian Institute of Oceanography
2025
Wuhan Institute of Physics and Mathematics
2020-2025
Chinese Academy of Sciences
2020-2025
Wuhan University
2021-2025
Renmin Hospital of Wuhan University
2021-2025
University of Chinese Academy of Sciences
2021-2025
Ministry of Agriculture and Rural Affairs
2022-2024
Soochow University
2013-2024
Natural resource scarcity, fossil fuel energy consumption, and total greenhouse gas emissions are critical issues that require immediate attention. With the global population steadily increasing economies expanding, demand for natural resources, particularly fuels, has experienced an unprecedented surge. This surge in consumption is directly linked to alarming rise emissions. The study examines nexus between agricultural nitrous oxide taking into account dynamics of agriculture, forestry,...
Abstract Background Rainbow trout are important fish for aquaculture and recreational fisheries serves as a model species research investigations associated with carcinogenesis, comparative immunology, toxicology evolutionary biology. However, to date there is no genome reference sequence facilitate the development of molecular technologies that utilize high-throughput characterizations gene expression genetic variation. Alternatively, transcriptome sequencing rapid efficient means discovery...
Hemostasis is achieved through the comprehensive effect of multiple pathways. A composite porous material was designed consisting silk fibroin (SF), gelatin (GA) and calcium alginate (CA), integrating good biocompatibility SF, swelling property GA hemostatic factor Ca2+ CA. Water absorption, platelet adhesion, fibrinogen adsorption, blood coagulation activity, cytotoxicity were investigated. Pore size in SF/GA materials increased with increasing content SF but decreased significantly SF/CA...
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are characterized by rapid onset widespread inflammation in the lungs, often leading to failure. These conditions can be triggered various factors, resulting a severe inflammatory response within lungs. Resveratrol, polyphenolic compound found grapes peanuts, is renowned for its potent antioxidative anti-inflammatory properties. In this study, we investigated how resveratrol protects against lipopolysaccharide...
SOX5 is a transcription factor with homology to the high mobility group box region of testis-determining factor, SRY. Both mouse and human genes encode 48-kDa protein (S-SOX5) that only present in tissues containing cells motile cilia/flagella. The mammalian sperm-associated antigen 6 gene (SPAG6) encodes an axoneme central apparatus protein. Because SPAG6 promoters contain multiple potential binding sites for SOX5, regulation by S-SOX5 was investigated BEAS-2B cells, line derived from...
Human Y-box binding protein 1 (YB-1) is a multifunctional and overexpressed in many types of cancer. It specifically recognizes DNA/RNA through cold shock domain (CSD) regulates nucleic acid metabolism. The C-terminal extension CSD the phosphorylation S102 are indispensable for YB-1 function. Until now, roles gene transcription translation still largely unknown. Here, we solved structure human with sequence (CSDex). reveals that interacts several residues conventional adopts rigid instead...
The periosteum plays an important role in bone formation and reconstruction. One of the reasons for high failure rate transplantation is absence periosteum. Silk fibroin (SF) silk sericin (SS) have excellent biocompatibility physicochemical properties, which amazing application prospects tissue engineering, but lacked mechanical properties. We developed a series SF/SS composite films with improved properties using boiling water degumming, caused little damage to SF molecular chains retain...
Abstract Background The accumulation and aggregation of α‐synuclein (α‐Syn) are characteristic Parkinson's disease (PD). Epidemiological evidence indicates that hyperlipidemia is associated with an increased risk PD. levels 27‐hydroxycholesterol (27‐OHC), a cholesterol oxidation derivative, in the brain cerebrospinal fluid patients However, whether 27‐OHC plays role α‐Syn propagation remains elusive. Objective aim this study was to determine regulates propagation. Methods Purified...
Aloe vera (L.) Burm.f. is a traditional Chinese medicine known for treating various ailments, including fungal infections. Aloin one of the major components from A. vera, but its antifungal mechanism and therapeutic potential against oral candidiasis are not clear. This study aimed to examine aloin Candida albicans inhibitory activity candidiasis. In this study, we first time found that could induce formation abnormal hyphae with smaller hyphal diameters fewer branching points in C. 11...
Parkinson’s disease (PD) is a neurodegenerative characterized by the death of dopaminergic neurons in substantia nigra and formation Lewy bodies that are composed aggregated α-synuclein (α-Syn). However, factors regulate α-Syn pathology nigrostriatal degeneration remain poorly understood. Previous studies demonstrate cholesterol 24-hydroxylase (CYP46A1) increases risk for PD. Moreover, 24-hydroxycholesterol (24-OHC), brain-specific oxysterol catalyzed CYP46A1, elevated cerebrospinal fluid PD...
As China’s agricultural sector modernizes, enhancing farmers’ sustainable work performance remains pivotal. This study examines how Servant Leadership directly and indirectly improves productivity in emerging entities, with Organizational Identity serving as a critical mediator. Structural equation modeling reveals two direct pathways: Altruism ( β = 0.124), where leaders prioritize well-being through equitable resource allocation personalized support, fostering trust reducing attrition;...
Expanded polystyrene (EPS) has caused significant pollution in marine environments, with potential EPS-degrading bacteria identified on long-term floating EPS biofilms. However, studies bacterial interactions and consortium reconstruction based in-situ diversity remain limited. Marine wastes of different sizes were collected from subtropical coast Xiamen island, subjected to analyses. Co-occurrence network characterization revealed that Rhodobacterales Rhizobiales play important roles (PS)...
Arginine-Glycine-Aspartate (RGD) tripeptide can promote cell adhesion when present in the amino acid of proteins such as fibronectin. In order to demonstrate bioactivity an RGD-containing silk protein, a gene encoding RGD motif-containing peptide GSGAGGRGDGGYGSGSS (–RGD–) derived from nonmulberry was designed and cloned, then multimerised inserted into commercial pGEX expression vector for recombinant (–RGD–)n peptides. Herein, we focus on two glutathione-S-transferase (GST)-tagged fusion...
The detection and classification of arrhythmias are crucial steps in diagnosing cardiovascular diseases. However, current deep learning-based methods often fail to consider both the morpho-logical temporal features electrocardiogram (ECG) simultaneously. Therefore, we propose a hybrid heartbeat method that combines Transformer multi branch convolutional neural networks (CNNs). Then, use fusion module stitch obtained from different classifiers. We performed three protocols on MIT-BIH...