A5074947008- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Head and Neck Cancer Studies
- Geology and Paleoclimatology Research
- Lower Extremity Biomechanics and Pathologies
- Orthopaedic implants and arthroplasty
- Lung Cancer Research Studies
- Osteoarthritis Treatment and Mechanisms
- Geological and Geochemical Analysis
- Shoulder Injury and Treatment
- Hydrocarbon exploration and reservoir analysis
- Head and Neck Surgical Oncology
- earthquake and tectonic studies
- Dermatologic Treatments and Research
- Geological and Geophysical Studies
- Geological Studies and Exploration
- Ear and Head Tumors
- Cancer Immunotherapy and Biomarkers
- Sports injuries and prevention
- melanin and skin pigmentation
- Inflammatory Myopathies and Dermatomyositis
- Spinal Fractures and Fixation Techniques
- Immune Response and Inflammation
- Advanced X-ray Imaging Techniques
- Skin Protection and Aging
Okayama University
1999-2025
Niigata University Medical and Dental Hospital
2024
Niigata University
2016-2024
Okayama University Hospital
2022-2024
Chiba University
2016-2022
The University of Tokyo
2015-2021
Japan Agency for Marine-Earth Science and Technology
2019-2021
Okayama Rosai Hospital
1979-2021
Planetary Science Institute
2021
Nagaoka Red Cross Hospital
2018-2019
Abstract Purpose The extent to which arthropathic changes progress after medial meniscus posterior root tear (MMPRT) repair remains controversial. This retrospective study assessed joint space (MJS) narrowing progression pullout for MMPRT and identified the correlating factors. Methods We included 56 patients who underwent MMPRT. MJS of bilateral knees was with radiography using fixed-flexion view. A second-look arthroscopy performed one year post-operatively all patients. baseline...
Abstract Purpose To reveal the outcomes of partial medial meniscus posterior root tears following transtibial pullout repair compared with complete radial tears. Materials and methods We retrospectively evaluated 15 consecutive patients (male/female, 5/10; average age, 64.4 years) who underwent for their results those 86 same surgery All second-look arthroscopy on 1 year postoperatively, a semi-quantitative meniscal healing score (anteroposterior width, stability, synovial coverage, total 10...
This study aimed to assess quadriceps muscle strength after medial meniscus (MM) posterior root repair and determine its relationship with clinical scores MM extrusion (MME).Thirty patients who underwent pullout for tear were evaluated preoperatively at 1 year postoperatively included in this study. Quadriceps was measured using the Locomo Scan-II instrument (ALCARE, Tokyo, Japan). MME (i.e., Knee Injury Osteoarthritis Outcome Score [KOOS], International Documentation Committee score,...
Abstract Purpose To assess postoperative progression of patellofemoral (PF) cartilage degeneration after medial meniscus posterior root (MMPR) repair and identify potential risk factors. Methods Data from patients who underwent transtibial pullout for complete radial MMPR tears between April 2018 October 2021 were retrospectively investigated. Patients with severe chondral lesions the PF joint at primary surgery excluded. All second‐look arthroscopy 12 months postoperatively. Postoperative...
Abstract Background We investigated whether the preoperative flexion tear gap (FTG) observed in open magnetic resonance imaging (MRI) affects meniscus stability after medial (MM) posterior root (MMPR) repairs. Furthermore, time-correlated MRI findings from MMPR occurrence were evaluated. Methods This retrospective observational study included 54 patients (mean age, 64.6 years; 13 males and 41 females) who underwent pullout repair for radial degenerative tear. Meniscus (scored 0–4 points) was...
Abstract Background Quality‐switched (QS) lasers are well‐known effective treatment for removing solar lentigines. However, the high incidence of post‐inflammatory hyperpigmentation (PIH) raises concern in darker skin types. This is first study comparing efficacies and incidences PIH Asian with different degrees irradiation between two QS lasers. Method In total, 355 lentigines 193 cases, types III–V, were randomly divided into four groups. All cases received single laser treatment. Clinical...
ObjectivesThis study aimed to investigate whether the initial suture tension when pullout sutures are fixed affects postoperative clinical outcomes following medial meniscus posterior root repair.MethodsThe data of 48 patients who underwent transtibial repair using two simple stitches (outer and inner sutures) with an additional all-inside posteromedial were retrospectively investigated. The sequentially divided into groups compare efficacy fixed: 30N Group (April 2019 September 2019, 24...
Meniscus cells have several distinct properties in cellular morphology and extracellular matrix production. Inner meniscus are considered to more chondrocytic phenotype compared with outer cells. However, the chondrogenic property of each cell has not been elucidated detail. In this study, we investigated difference between human inner meniscus-derived deposition potential. Monolayer-cultured showed small ovoid shapes though slender fibroblastic were obtained from half meniscus. The...
Abstract Background Paget’s disease is an intraepidermal adenocarcinoma that difficult to diagnose clinically as it mimics inflammatory or infectious diseases. As a consequence, may be misdiagnosed resulting in delay appropriate management. Reflectance confocal microscopy allows the visualization of upper layers skin and mucosa at cellular resolution. characterized histologically by presence neoplastic cells scattered throughout all epidermis pattern similar also observed melanoma (and...
Monopolar radiofrequency (mRF) devices have been shown to be clinically effective for treating aging skin, but there are few histologic studies about the mechanisms.To histologically analyze chronologic and quantitative change in collagens after mRF treatment determine mechanisms of antiaging effect.Five patients were enrolled this study. Skin specimens taken before 1 3 months treatment. Immunostaining was performed type I III collagen levels stem other cell counts skin layers.In all cases,...
We previously reported that high expression of procollagen‑lysine 2‑oxoglutarate 5‑dioxygenase 2 (PLOD2) leads to stabilization and plasma membrane translocation integrin β1 promote the invasion metastasis oral squamous cell carcinoma (SCC). The present study aimed further understand relationship between PLOD2‑integrin signaling tumor microenvironment. This provided advanced insights indicating elevated interleukin (IL)‑6 in microenvironment acts as a key molecule triggers axis‑derived...
Bipolar radiofrequency (RF) technology is developed based on fractional thermolysis, and the literature concerning efficacy of rejuvenation treatment acne scars has been reported in Europe United States America. Therefore, we examined bipolar RF using thermolysis to evaluate safety Asian photo-aging skin, particularly 'wrinkles' 'sagging.' Ten Japanese women (mean age: 58.6, skin type III-IV) received three treatments every 4-6 weeks. For objective evaluation, evaluated improvement wrinkles...
Abstract The meniscus is a fibrocartilaginous tissue that plays an important role in controlling complex biomechanics of the knee. A perimeniscal capillary plexus supplies outer meniscus, whereas inner composed avascular tissue. Anti‐angiogenic molecules, such as chondromodulin‐I (ChM‐I) and endostatin, have pivotal roles preserving avascularity cartilage. However, anti‐angiogenic ChM‐I unclear meniscus. We hypothesized might maintain its feature by expressing ChM‐I. Immunohistochemical...
In the treatment of polymyositis (PM) and dermatomyositis (DM), muscle inflammation underlying autoimmunity need to be suppressed promptly; however, catabolic effects corticosteroids such as myopathy can detrimental in PM/DM. this study, we aimed assess corticosteroid-sparing effect tacrolimus initial PM/DM.We retrospectively identified 19 PM/DM patients who received with prednisolone at an dose 1 mg/kg/day (Conventional Monotherapy, our standard therapy before 2008) 23 plus 0.8 (Tacrolimus...
Objective Recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) treatment has changed dramatically with the introduction of immune checkpoint inhibitors (ICIs). However, there are few reports outcomes on HNSCC distant metastasis (M1) at initial diagnosis, its strategy not been standardized. We aimed to analyze outcome prognostic factors patients M1 disease. Methods In this multi‐institutional retrospective study, 98 were initially diagnosed disease between 2007 2021. The divided...
Abstract Introduction Immune‐related adverse events (irAEs) are prognostic factors for patients on nivolumab. However, predictors of irAEs have not yet been identified. We aimed to investigate the occurrence and nivolumab discontinuation due irAEs. Methods Sixty‐two with recurrent/metastatic head neck squamous cell carcinoma received therapy between June 2017 December 2020. Treatment outcome was compared groups or without The irAE (+) group further divided by discontinuation....
In allergic asthma, environmental allergens including house dust mite (HDM) trigger pattern recognition receptors and activate downstream signaling pathways NF-κB not only in immune cells but also airway epithelial cells. Recent studies have shown that activation is regulated positively or negatively depending on the cellular context by IκBNS (encoded gene Nfkbid), one of atypical IκB proteins, nucleus. Therefore, we hypothesized expressed involved regulation asthmatic responses.To determine...
We examined the role of lateral temporal bone resection (LTBR) in treatment external ear canal (EAC) carcinoma between 2007 and 2018. The estimated 3-year disease-free survival (DFS) disease-specific (DSS) according to tumor stage treatments were investigated 36 patients with EAC squamous cell carcinoma. T classification University Pittsburgh staging system was as follows: 14 T1, four T2, nine T3, T4. DFS rate 77.4% for T1 tumors, 100% 44.4% T3 11.1% T4 tumors ( p < 001). DSS T1/T2...