A5113831243- Antibiotic Use and Resistance
- Glycosylation and Glycoproteins Research
- Inhalation and Respiratory Drug Delivery
- Antifungal resistance and susceptibility
- Aortic Disease and Treatment Approaches
- Non-Invasive Vital Sign Monitoring
- biodegradable polymer synthesis and properties
- Chemical Synthesis and Analysis
- Synthetic Organic Chemistry Methods
- Pneumonia and Respiratory Infections
- Cancer, Lipids, and Metabolism
- Molecular spectroscopy and chirality
- Cardiovascular Health and Disease Prevention
- Lipoproteins and Cardiovascular Health
- Cardiac, Anesthesia and Surgical Outcomes
- Porphyrin and Phthalocyanine Chemistry
- Advanced Polymer Synthesis and Characterization
- Organometallic Complex Synthesis and Catalysis
- Blood Pressure and Hypertension Studies
- Aortic aneurysm repair treatments
- Tracheal and airway disorders
- Lysosomal Storage Disorders Research
- Galectins and Cancer Biology
- Vector-Borne Animal Diseases
- Semiconductor materials and devices
Yamagata University Hospital
2025
University of Toyama
2024
Keio University
2023
Tokushima University
2008-2018
Hiroshima University
2012
Nagoya University
1965-2011
Nagasaki University Hospital
2010
Niigata University
1977-2009
Yokohama City University Medical Center
2007
Aichi Shukutoku University
2007
Gangliosides, sialic acid-containing glycosphingolipids, are abundant in the vertebrate (mammalian) nervous system. Their composition is spatially and developmentally regulated, gangliosides have been widely believed to lay essential roles establishment of system, especially neuritogenesis synaptogenesis. However, this has never tested directly. Here we report generation mice with a disrupted beta 1,4-N-acetylgalactosaminyltransferase (GM2/GD2 synthase; EC 2.4.1.92) gene. The lacked all...
Pre beta 1-HDL promotes cholesterol efflux from cell membranes. Its plasma concentration is regulated by lecithin: acyltransferase (LCAT). To clarify whether the of pre changes in coronary artery disease (CAD), we determined distribution apolipoprotein A-I (apoA-I) among HDL subfractions 20 CAD patients and healthy controls, using nondenaturing two-dimensional gel electrophoresis. We found that had significantly higher concentrations than controls [7.6% +/- 3.4% vs 4.6% 2.3% apoA-I (P <...
The patient is a 70-year-old male who developed back pain in May 2021. He was diagnosed with ureteral stone and type 2 diabetes (T2D) an HbA1c of 9.3% After successful operation, he continued treatment for T2D. Pulse wave velocity (PWV) showed ankle-brachial index (ABI) 0.78/0.83 (R/L) cardio-ankle vascular (CAVI) 12.9/13.9, suggesting arteriosclerosis peripheral artery disease (PAD). Computed tomography (CT) movable lesion adjacent to the right heart, pericardial cyst. had been stable after...
Summary Blood transfusion is one of the causes anaphylaxis during general anaesthesia. In most cases, adrenaline administration quickly alleviates circulatory failure and its continuous for days very rare. We present case a 79‐year‐old man who experienced prolonged anaphylactic with increased histamine tryptase concentrations following laparoscopic total gastrectomy, which he received blood transfusion. He developed hypotension soon after initiation surgery. immediately administered...
The patient is a 73-year-old male with type 2 diabetes (T2D) and hypertension, treated for years various oral hypoglycemic agents (OHAs) an anti-hypertensive agent (AHA). His HbA1c levels were unstable during 2020-2022, which time he was prescribed linagliptin, voglibose, metformin. In 2023, his increased to 8.4%, imeglimin (Twymeeg) initiated. This resulted in acute reduction of 6.5% over 5 months. A pulse wave velocity (PWV) examination, using sphygmograph, showed stable values the...
Abstract Copolymerization of 1,3‐dioxolane with tetrahydrofuran, 3,3‐bis(chloromethyl)oxacyclobutane, and 4‐chloromethyl‐1,3‐dioxolane were performed using boron fluoride etherate as catalyst. The monomer reactivity ratios at 0°C. determined. plot log 1/r 1 vs. pK b each gave a straight line, which suggests that basicity cyclic ethers may be important in determining their cationic copolymerization.
Solar irradiance is fundamental data crucial for analyses related to weather and climate. High-precision estimation models are necessary create areal solar irradiance. In this study, we developed a novel model by utilizing machine learning multiband from meteorological satellite observations. Particularly under clear-sky thin clouds, observations can be influenced surface reflections, which may lead overfitting ground To make the applicable at any location, constructed incorporating prior...
The relationship between arterial pulse-wave velocity and the possible factors (age, gender, blood pressure, heart rate, serum lipids, disease state) involved were examined for 127 subjects using multivariate analysis. Since a preliminary study had shown that age correlated highly with transmission time of pulse waves rather than their velocity, former was used in this Transmission obtained from transit fingertip-pulse toetip-pulse waves, as estimated delay initial rise each six frequency...
Pulse wave velocity (PWV) is related to arterial wall elasticity, which in part regulated by sympathetic nervous system activity. The present study investigated the potential for simultaneous use of PWV and heart rate variability using noninvasive recordings order provide a quantitative evaluation sympathovagal interaction modulating cardiovascular functions. We obtained 10 indices from (HR) time series 92 healthy subjects (control group) compared results with those 135 patients diabetes...
Abstract Disease-modifying antirheumatic drugs (DMARDs) are expected to relieve polyarthritis, and thereby improve the patient's quality of life eventually alter prognosis rheumatoid arthritis (RA) or progressive joint destruction caused by it. DMARDs may cause adverse reactions become less effective over time in some patients. Using changes disease activity X-ray findings as indicators, we retrospectively evaluated long-term results step-wise administration 200 patients with RA. The had...
Gangliosides have been thought to be tumor markers of various neuroectoderm-derived cancers. However, their roles in malignant phenotypes cancer cells are not well understood. We performed the remodeling ganglioside profiles mouse melanoma B16 (B78 subline) by introducing GM2/GD2 synthase cDNA, and analyzed phenotypic changes such as cell morphology, growth, adhesion c-fos gene expression. Although newly expressed GM2 was clearly detected, GM2-positive transfectant showed rather reduced...
Low-power dry-etching process has been adopted to study the influence of on Ohmic contact p-GaN. When surface layer as-grown p-GaN was removed by low-power SiCl4/Cl2-etching, no can be formed dry-etched The same also applied n-GaN understand process. By capacitance-voltage (C-V) measurement, Schottky barrier heights (SBHs) and were measured. comparing change measured SBHs n-GaN, it suggested that etching damage is not only reason responsible for degraded contacts formatin, original have some...