- Metal complexes synthesis and properties
- Ferrocene Chemistry and Applications
- Supramolecular Chemistry and Complexes
- Asymmetric Hydrogenation and Catalysis
- Organometallic Complex Synthesis and Catalysis
- Chemical Synthesis and Analysis
University of Ljubljana
2023-2024
Synthesis, characterization, solution speciation, binding affinity towards biomolecules and anticancer activity of organometallic Ru( ii ), Rh( iii ) Re( i complexes ( N , donor 5α-dihydrotestosterone-based hybrid ligands.
In this study, we report the synthesis and characterization of 12 novel rhenium(I) complexes with general formula
Organoruthenium pyrithione (1-hydroxypyridine-2-thione) complexes have been shown in our recent studies to be a promising family of compounds for development new anticancer drugs. The complex [(η6-p-cymene)Ru(pyrithionato)(pta)]PF6 contains phosphine ligand pta (1,3,5-triaza-7-phosphaadamantane) as functionality that improves the stability and its aqueous solubility. Here, we report efforts find alternatives discover structural elements improve biological properties ruthenium was replaced by...