A5100645807- Zebrafish Biomedical Research Applications
- Electromagnetic wave absorption materials
- Calpain Protease Function and Regulation
- Epigenetics and DNA Methylation
- Advanced Sensor and Energy Harvesting Materials
- Neuroinflammation and Neurodegeneration Mechanisms
- RNA modifications and cancer
- Pharmacological Effects of Natural Compounds
- Berberine and alkaloids research
- Yeasts and Rust Fungi Studies
- Neurofibromatosis and Schwannoma Cases
- Physical Activity and Health
- Intracerebral and Subarachnoid Hemorrhage Research
- Machine Learning in Healthcare
- Spinal Hematomas and Complications
- ATP Synthase and ATPases Research
- Artificial Intelligence in Healthcare
- Nuclear Structure and Function
- Supply Chain Resilience and Risk Management
- Ginseng Biological Effects and Applications
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Software Reliability and Analysis Research
- Cancer, Hypoxia, and Metabolism
- Economics of Agriculture and Food Markets
- Silk-based biomaterials and applications
Beijing University of Chemical Technology
2022-2025
Shandong Academy of Sciences
2022-2025
Qilu University of Technology
2022-2025
Shandong First Medical University
2024
Peking University
2021-2024
Zhejiang University
2024
Chinese PLA General Hospital
2023-2024
Zhejiang Center for Disease Control and Prevention
2023
Soochow University
2022
University of Toronto
2020
Traditional electromagnetic interference–shielding materials are predominantly electrically conductive, posing short-circuit risks when applied in highly integrated electronics. To overcome this dilemma, we propose a microcapacitor-structure model comprising conductive fillers as polar plates and intermediate polymer dielectric layer to develop insulating composites. The electron oscillation dipole polarization layers contribute the reflection absorption of waves. Guided by this, synergistic...
The flexible and conductive MXene grid/silver nanowire hierarchical film exhibits both high optical transmittance excellent electromagnetic interference shielding efficiency.
Hematoma clearance, which is achieved largely by phagocytosis of erythrocytes in the hemorrhagic brain, limits injury and facilitates recovery following intracerebral hemorrhage (ICH). Efficient critically depends on capacity a single phagocyte to phagocytize dead cells continually. However, mechanism underlying continual ICH remains unclear. We aimed investigate this study. By using models, we found that gasotransmitter hydrogen sulfide (H2S) an endogenous modulator ICH. The expression H2S...
Abstract Although electrically conductive Ti₃C₂T x MXene fibers are promising for wearable electronics, the poor inter‐sheet interactions and random stacking structure of sheets seriously hinder electron transport load transfer fibers. Herein, mechanically strong MXene@graphene oxide (GO) core‐shell fabricated with a coaxial wet‐spinning methodology electromagnetic wave regulation, thermochromic alerts, visible camouflage. During wet‐spinning, trace‐carboxylated GO in shell align readily...
Xanthatin, a sesquiterpene lactone compound, isolated from Chinese herb, Xanthium strumarium L, has various activities, including anti-inflammatory, anti-tumor, anti-ulcer effects. However, it been less studied in terms of its toxicity, especially the potential toxicity on heart. This study is mainly aimed to assess cardiotoxicity xanthatin vivo using zebrafish larva and vitro cardiomyocytes H9C2. The was assessed by pericardial edema, blood flow dynamics, SV-BA distance, sub-intestinal...
ING5 belongs to the inhibitor of growth (ING) candidate tumor suppressor family, which is involved in multiple cellular functions, such as cell cycle regulation, apoptosis, and chromatin remodelling. Previously, we reported that overexpression inhibits EMT by regulating EMT-related molecules, including Snail1, at mRNA protein levels. However, mechanisms remain unclear. In current study, identify induces upregulation miR-34c-5p. The expression levels both miR-34c-5p NSCLC tissues from TCGA...
Loss of Nemp leads to softening the germline nuclear envelope and loss fertility.
Trichosanthis fruit (TF) is a classic medicinal material obtained from Shandong, China. The peel of this (Trichosanthis pericarpium, TP) known to exert anti-thrombotic effects. However, the active components and mechanisms TP have yet be fully elucidated. Combined with zebrafish models high-performance liquid chromatography (HPLC), study evaluated endogenous effects combination three compounds TP. First, we used HPLC investigate in water extract Next, model activity compound combinations by...
Abstract: Panax notoginseng has the effect of stimulating circulation to end stasis. Our study was designed evaluate anti-thrombotic protoparaxotriol saponins (PTS) from P. and involved mechanisms. A thrombosis model constructed, activity PTS determined by erythrocyte staining, heart rate, blood flow velocity. In addition, quantitative real-time polymerase chain reaction used identify changes in expression genes related coagulation, inflammation, apoptosis. alleviated arachidonic...
Guizhi granules mainly treat colds and improve overall health. They are widely used in clinical practice, but their protective effect anti-inflammatory mechanism against influenza unclear. In this study, the therapeutic of on was verified vitro. The active compounds, targets, cellular pathways were predicted using network pharmacology. protein-protein interaction component-target networks identified 5 core targets (JUN, TNF-α, RELA, AKT1, MAPK1) components (dihydrocapsaicin, kumatakenin,...
Many long non-coding RNAs(lncRNAs) have been found to be a good marker for several tumors. Using lncRNA-mining approach, we aimed identify lncRNA expression signature that can predict breast cancer patient survival. We performed LncRNA profiling in 887 patients from Gene Expression Omnibus (GEO) datasets. The association between and clinical survival was analyzed using the training set(n = 327, GSE 20685). validation another three independent testing sets(252 GSE21653, 204 GSE12276, 104...
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Chelerythrine (CHE), a natural benzophenanthridine alkaloid, possesses various biological and pharmacological activities, such as antimicrobial, antitumor anti-inflammatory effects. However, its adverse side effect has not been fully elucidated. Therefore, this study was designed to investigate the developmental toxicity of CHE in zebrafish. We found that could lead notably increase mortality malformation rate, while reduction hatching rate body length decrease. also can affect normal...