A5102374475- Heavy Metal Exposure and Toxicity
- Hepatitis B Virus Studies
- Systemic Lupus Erythematosus Research
- Immunodeficiency and Autoimmune Disorders
- RNA Interference and Gene Delivery
- Trace Elements in Health
- FOXO transcription factor regulation
- Vitamin D Research Studies
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Refrigeration and Air Conditioning Technologies
- Eosinophilic Disorders and Syndromes
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Exercise and Physiological Responses
- Protein Kinase Regulation and GTPase Signaling
- Heavy metals in environment
- Muscle Physiology and Disorders
- Systemic Sclerosis and Related Diseases
- Innovative Educational Techniques
- Advanced Combustion Engine Technologies
- Educational Reforms and Innovations
- Selenium in Biological Systems
- Turbomachinery Performance and Optimization
- Adenosine and Purinergic Signaling
- Heavy Metals in Plants
Sun Yat-sen University
2024-2025
Nanjing Medical University
2020-2025
Anhui University of Science and Technology
2013-2014
ABSTRACT Background Although the role of vitamin D receptor (VDR) in muscle mass and strength is well established, effects (VD) on remain controversial due to various factors. Herein, influence sex VD function underlying reasons was explored. Methods Male female Sod1 gene knockout (SKO) mice, serving as a model for skeletal atrophy, were treated with active analogue calcipotriol, RNA sequencing employed investigate this potential signalling pathway. The National Health Nutrition Examination...
Protein kinase C (PKC) family is evolutionally conserved and involved in various signaling cascades all cells. Of the family, PRKCQ dominatingly expressed testis, however, its molecular functionality spermatogenesis male fertility remains unclear. To evaluate role of spermatogenesis, Prkcq knockout mice were generated using CRISPR/Cas9 system. Histological immunofluorescence assays by different markers employed to assess testicular cells variation. Sperm parameters analyzed computer-assisted...
Objective. Anti-DFS70 antibodies correlating with the nuclear dense fine speckled (DFS) pattern in HEp-2 indirect immunofluorescence assay (IFA) are less common patients systemic autoimmune rheumatic disease (SARD) than healthy subjects and their clinical associations remain elusive. We hosted a multi-center IFA training program to improve ability of laboratories recognize DFS investigate prevalence relevance anti-DFS70 antibodies. Methods. sera identified by 29 centers China were redirected...
Background/Objectives: As a hyperaccumulator of selenium (Se), Cardamine violifolia (Cv) and its peptide extract could ameliorate the negative effects high-fat diet (HFD). However, coaccumulation cadmium (Cd) in Se-enriched Cv (Cv2) potential confounding effect on roles enriched Se remain unknown. We aimed to investigate whether Cv2 alleviate HFD-induced lipid disorder liver damage. Methods: Three groups 31-week-old female mice were fed for 41 weeks (n = 10–12) with control Cv-supplemented...
The association between heavy metal exposure and diabetes is controversial vitamin E (VE) may reduce risk. We aimed to examine the associations blood metals (BHMs) risk VE's role in relationship. From 2007-2018 NHANES, 10,721 participants aged ≥ 18 were included for multiple statistical analyses, which revealed that BHMs dietary VE intake negatively associated with fasting plasma glucose (FPG). prevalence each quartile (Q) of increased age, but within age Q4, it generally decreased...