- Olfactory and Sensory Function Studies
- Parkinson's Disease Mechanisms and Treatments
- Biochemical Analysis and Sensing Techniques
- Advanced Chemical Sensor Technologies
- Neurogenetic and Muscular Disorders Research
- Voice and Speech Disorders
- Cerebral Venous Sinus Thrombosis
- Neurological disorders and treatments
- Intracranial Aneurysms: Treatment and Complications
- RNA Research and Splicing
- Neurosurgical Procedures and Complications
- Botulinum Toxin and Related Neurological Disorders
- Amyotrophic Lateral Sclerosis Research
University of Sassari
2020-2023
Azienda Ospedaliero Universitaria di Sassari
2022
Olfactory and cognitive disorders represent important non-motor symptoms in Parkinson's disease (PD). No clear evidence was reported about association of specific domains olfactory impairment.The aim this study to evaluate the between dysfunction PD patients compared controls.178 98 controls were enrolled evaluated for odor threshold (OT), discrimination (OD), identification (OI), TDI score using Sniffin' Sticks test. Cognitive function Montreal Assessment scale with six sub-scores:...
Human endogenous retrovirus (HERV)-K env-su glycoprotein has been documented in amyotrophic lateral sclerosis (ALS), where HERV-K 19–37 antibody levels significantly correlated with clinical measures of disease severity. Herein, we investigated further the humoral and cell-mediated immune response against specific antigenic peptides derived from ALS. env expression on peripheral blood mononuclear cells (PBMCs) membrane cytokines chemokines after stimulation 109–126 were quantified patients...
Olfactory impairment and REM sleep behavior disorder (RBD) are common non-motor symptoms in Parkinson's disease (PD) patients, often preceding the onset of specific motor and, thus, crucial for strategies directed to anticipate PD diagnosis. In this context, interaction between olfactory RBD has not been clearly defined.The aim study was determine possible role other clinical characteristics as predictors higher scores at screening questionnaire (RBDSQ) a large population patients.In study,...
Currently, Parkinson’s Disease (PD) is diagnosed primarily based on symptoms by experts clinicians. Neuroimaging exams represent an important tool to confirm the clinical diagnosis. Among them, Brain Parenchyma Sonography (BPS) used evaluate hyperechogenicity of Substantia Nigra (SN), found in more than 90% PD patients. In this article, we exploit a new dataset BPS images investigate automatic segmentation approach for SN that can increase accuracy exam and its practicability routine. This...
The objective of our description is to shed light on some new hemodynamic and clinical characteristics in the unstable cerebral aneurysm Case: We describe a 54 year old woman who presented tension headache, that increasing for several days. A CT scan performed ER suggests possible arterial ectasia at level circle Willis. patient hospitalized. An angio shows an anterior communicating artery, without signs fixation and/or other instability. subsequent TCCD examination with venous study clear...