Hua Fan

ORCID: 0009-0006-1027-9182
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About
Contact & Profiles
Research Areas
  • Advanced Database Systems and Queries
  • MicroRNA in disease regulation
  • Patient Satisfaction in Healthcare
  • Healthcare Policy and Management
  • Natural product bioactivities and synthesis
  • Data Management and Algorithms
  • Total Knee Arthroplasty Outcomes
  • Data Mining Algorithms and Applications
  • Knee injuries and reconstruction techniques
  • Ferroptosis and cancer prognosis
  • Cancer-related molecular mechanisms research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Bioactive Compounds and Antitumor Agents
  • Cancer, Hypoxia, and Metabolism
  • Healthcare Systems and Reforms
  • Osteoarthritis Treatment and Mechanisms
  • Peptidase Inhibition and Analysis
  • Silkworms and Sericulture Research
  • Helicobacter pylori-related gastroenterology studies
  • Hepatitis C virus research
  • Gastric Cancer Management and Outcomes
  • Cancer Mechanisms and Therapy

Gansu University of Traditional Chinese Medicine
2024

Gansu Provincial Hospital
2024

Hainan Medical University
2017-2023

Peking University
2021-2022

Peking University Cancer Hospital
2021-2022

Hudson Institute
2020

John Wiley & Sons (United States)
2020

Molecular features underlining the multistage progression of gastric lesions and development early cancer (GC) are poorly understood, restricting ability to GC prevention management.We portrayed proteomic landscape explored signatures associated with risk GC. Tissue profiling was conducted for a total 324 subjects. A case-control study performed in discovery stage (n=169) based on populations from Linqu, known high-risk area China. We then two-stage validation, including cohort Linqu (n =...

10.1016/j.ebiom.2021.103714 article EN cc-by-nc-nd EBioMedicine 2021-11-22

Integration reforms have been piloted as key policies to address the fragmented health insurance system in China. They are also regarded a better choice for realizing Universal Basic Medical Insurance System (UBMIS). This study has attempted explore determinants that may affect respondents' dissatisfaction with reforms. The aim is provide evidence more effective policy adjustment during next round of nationwide integration A cross-sectional questionnaire survey was conducted Ningbo,...

10.1093/heapol/czx173 article EN cc-by-nc-nd Health Policy and Planning 2017-11-15

Early detection of gastric cancer (GC) remains challenging. We aimed to examine urine proteomic signatures and identify protein biomarkers that predict the progression lesions risk GC.A case-control study was initially designed, covering subjects with GC different stages. Subjects were aged 40-69 years, without prior diagnosis renal or urological diseases. enrolled a total 255 subjects, 123 in discovery stage from Linqu, China, high-risk area for 132 validation Linqu Beijing. A prospective...

10.1016/j.ebiom.2022.104340 article EN cc-by-nc-nd EBioMedicine 2022-11-07

Saikosaponin A (SSA) has been revealed to have anti-breast cancer (BC) effect. However, the association between SSA and BC glycolysis is obscure. We want probe function mechanism of on glycolysis. Kaplan-Meier plotter relationship STAT3 survival curve BC. The protein kinase B (Akt)/signal transducer activator transcription 3 (STAT3) pathway viability in cells treated with or without 0, 5, 10, 15 μM were assessed by Western blot cell counting kit-8. biological behaviors, lactate, ATP...

10.1111/cbdd.14259 article EN Chemical Biology & Drug Design 2023-04-23
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