A5076863384- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Hereditary Neurological Disorders
- Stroke Rehabilitation and Recovery
- Neurological Disease Mechanisms and Treatments
- Cardiac Imaging and Diagnostics
- Intracranial Aneurysms: Treatment and Complications
- Coronary Interventions and Diagnostics
- Cerebrovascular and genetic disorders
- Neurological Disorders and Treatments
- Neurogenesis and neuroplasticity mechanisms
- Sleep and Wakefulness Research
- MicroRNA in disease regulation
- Peripheral Neuropathies and Disorders
- Cardiovascular Health and Disease Prevention
- Traumatic Brain Injury and Neurovascular Disturbances
- Autoimmune Neurological Disorders and Treatments
- Neuroscience and Neuropharmacology Research
- Epilepsy research and treatment
- Parkinson's Disease Mechanisms and Treatments
- Genetic Neurodegenerative Diseases
- Venous Thromboembolism Diagnosis and Management
The Fifth People’s Hospital of Suzhou
2021-2024
People's Liberation Army No. 150 Hospital
2013
Chinese People's Liberation Army
2013
<h3>BACKGROUND AND PURPOSE:</h3> There are limited studies on the morphologic characteristics of MCA atherosclerotic stenosis. Our aim was to quantitatively assess remodeling pattern and plaque distribution MCAs with 3T high-resolution MR imaging. <h3>MATERIALS METHODS:</h3> Eighty-seven consecutive patients symptomatic stenoses at M1 segment DSA (50%–99%) were enrolled. The index calculated as Vessel Area Maximal Lumen Narrowing/Reference Area. A ≥ 1.0 defined positive remodeling, a <...
Neurogenesis plays an important role in the prognosis of stroke patients and is known to be promoted by activation Notch1 signaling pathway. Studies on airway epithelium have shown that miR-449b represses Notch The study aimed investigate whether limb remote ischemic conditioning (LRIC) was able promote neurogenesis cerebral mice, miR-449b/Notch1 pathway LRIC-induced neuroprotection. Male C57BL/6 mice (22–25 g) were subjected transient middle artery occlusion (MCAO), LRIC performed bilateral...
Abstract Objective This study aimed to explore the effect of different administration routes a low dose tirofiban on acute ischemic stroke (AIS) patients with successful recanalization after endovascular treatment (EVT). Methods is cohort that retrospectively analyzed data AIS who underwent EVT and achieved from prospective registry. Eligible were divided into three groups according their use tirofiban. Propensity score matching (PSM) was used balance baseline bias. Safety outcomes included...
Objectives The present study was designed to evaluate the effects of total cerebral small vessel disease (CSVD) on early-onset depression after acute ischemic stroke (AIS), and develop a new nomogram including CSVD burden predict post-stroke (PSD). Methods We continuously enrolled patients with AIS who were hospitalized at First Affiliated Hospital Soochow University between October 2017 June 2019. All assessed for depressive symptoms using 17-item Hamilton Depression Scale (HAMD-17) 14 ± 2...
Anti-ganglioside antibodies (AGA) play an essential role in the development of Miller-Fisher syndrome (MFS). The positive rate ganglioside was exceptionally high MFS, especially anti-GQ1b antibodies. However, presence other does not exclude MFS.We present a 48-year-old male patient who suddenly developed dizziness, visual rotation, nausea, and vomiting accompanied by unsteady gait diplopia for 3 days before presentation to our clinic.On physical examination, patient's right eye could fully...
Cerebral small vessel disease (CSVD) often coexists with cognitive dysfunction in patients, leading to significant challenges treatment and management. This study aimed examine the efficacy of combined application donepezil nimodipine on patients comorbid CSVD effects patients' albumin prealbumin levels.
Rationale: Neuronal intranuclear inclusion disease (NIID) is a slowly progressing neurodegenerative with various manifestations and high heterogeneity. Clinical characteristics, imaging, skin biopsy, genetic testing are necessary for its diagnosis. Electromyography may also be useful tool diagnosing NIID. In this study, we report patient motor sensory nerve demyelination changes accompanied by axonal damage. Patient concerns: A 64-year-old woman was admitted to our department gradually...
Thrombectomy greatly improves the clinical prognosis of patients with acute ischemic stroke (AIS). The aim this study is to develop a nomogram model that can predict undergoing thrombectomy.We retrospectively collected information who were admitted Green Channel First Affiliated Hospital Soochow University from September 2018 May 2022. main outcome was defined as three-month unfavorable (modified Rankin Scale 3-6). Based on results multivariate regression analysis, established. We tested...