A5076893743- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Sepsis Diagnosis and Treatment
- Anatomy and Medical Technology
- Innovations in Medical Education
- Nerve injury and regeneration
- Mass Spectrometry Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Computational Drug Discovery Methods
- Surgical Simulation and Training
- Immune Response and Inflammation
- Healthcare and Venom Research
- Clinical Reasoning and Diagnostic Skills
- Trauma and Emergency Care Studies
- Nutrition and Health in Aging
- Workplace Health and Well-being
- Acupuncture Treatment Research Studies
- Protein Structure and Dynamics
- Spinal Cord Injury Research
- Clinical Nutrition and Gastroenterology
- Atherosclerosis and Cardiovascular Diseases
- Chronic Disease Management Strategies
- Pain Mechanisms and Treatments
- Resilience and Mental Health
Sun Yat-sen University
2006-2024
The Fifth People’s Hospital of Suzhou
2023-2024
Inner Mongolia Medical University
2012-2023
Weatherford College
2023
Inner Mongolia Medical College Hospital
2012-2022
University of South China
2022
Mongolian National University of Medical Sciences
2022
Hainan Medical University
2022
Changsha Central Hospital
2022
Hainan Medical College Hospital
2021
Introduction Information about sepsis in mainland China remains scarce and incomplete. The purpose of this study was to describe the epidemiology outcome severe septic shock mixed ICU China, as well independent predictors mortality. Methods We performed a 2-month prospective, observational cohort 22 closed multi-disciplinary intensive care units (ICUs). All admissions into those ICUs during period were screened patients with or included. Results A total 484 patients, 37.3 per 100 diagnosed...
Phospholipids (PLs) are the major building block molecules of cellular membranes. Their composition varies depending on cell types and compartments. Thus, information regarding PL distribution in tissue has important physiological pathological significance. Recent developments imaging mass spectrometry (IMS) have allowed complete mapping species tissue. The IMS technique can detect different classes PLs as well their location directly from sections. head groups carry either positive and/or...
We sought to describe the demographics, case mix, interventions, and clinical outcome of critically ill patients admitted ICUs in Mainland China.A 2-month (July 1, 2009, August 31, 2009) prospective, observational cohort study.Twenty-two China.Adult participating during study period with an ICU length stay >24 hrs.None.Patient characteristics, including underlying diseases, severity illness, admission status, complications, intervention treatment stay, were recorded report form. The primary...
Abstract Background Previous cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain effects guideline implementation on patient-centered outcomes. Methods We conducted a multicenter, cluster-randomized, parallel-controlled trial intensive care units (ICUs) across China. developed...
Abstract We investigated the functional recovery of motoneurons after reimplanting an avulsed ventral root in a rat model traction injury. The eighth cervical (C8) was by controlled and immediately reimplanted to spinal cord. Spinal nerves from neighbouring segments (C5, C6, C7 T1) were ligated cut. After 12 or 20 weeks, survival, regeneration evaluated Nissl staining, retrograde labelling motoneurons, NOS histochemistry, histological examination muscle nerve–muscle junction,...
Background In order to identify novel chemical classes of β-secretase (BACE-1) inhibitors, an alternative scoring protocol, Principal Component Analysis (PCA), was proposed summarize most the information from original functions and re-rank results virtual screening against BACE-1. Method Given a training set (50 BACE-1 inhibitors 9950 inactive diverse compounds), three rank-based methods, individual scoring, conventional consensus PCA, were judged by hit number in top 1% ranked list. The...
Abstract Background One of the most important objectives modern medical education is to empower students become humanistic clinicians. Human anatomy plays a crucial role in this mission by using cadavers cause reflections on death, dying, illness, and practitioners care. The objective study was introduce, describe, evaluate impact ceremony honor body donors ethical attitudes students. Methods We used phenomenological research approach explore understand lived experiences teachers as they...
Poor inter-rater reliability in chest radiograph interpretation has been reported the context of acute respiratory distress syndrome (ARDS), although not for Berlin definition ARDS. We sought to examine effect training material on accuracy and consistency intensivists' interpretations ARDS diagnosis. conducted a rater agreement study which 286 intensivists (residents 41.3%, junior attending physicians 35.3%, senior physician 23.4%) independently reviewed same 12 radiographs developed by...
Although a large body of evidence has shown that peripheral nerve injury usually induces neuropathic pain, there are also clinical studies demonstrating the sural nerve, which almost only innervates skin, fails to do so. The underlying mechanism, however, is largely unknown. In present work, we found transection either gastrocnemius-soleus (GS) innervating skeletal muscle or tibial supplying both and but not produced lasting mechanical allodynia thermal hyperalgesia in adult rats....
Abstract Background The inhibition of the activity β-secretase (BACE-1) is a potentially important approach for treatment Alzheimer disease. To explore mechanism inhibition, we describe use 46 X-ray crystallographic BACE-1/inhibitor complexes to derive quantitative structure-activity relationship (QSAR) models. inhibitors were aligned by superimposing complexes, and gCOMBINE software was used perform COMparative BINding Energy (COMBINE) analysis on these minimized . major advantage COMBINE...
// Li-peng Zhang 1, * , Yan Zhao 2, Guo-juan Liu 1 Da-gang Yang Yi-huan Dong Li-hua Zhou Department of Critical Care Medicine, The Affiliated Hospital Innner Mongolia Medical University, Hohhot 010050, China 2 Neurology, people' Inner Mongolia, 010050 These authors contributed equally to this work Correspondence to: Zhou, email: rocboy2008@aliyun.com Keywords: glabridin, acute respiratory distress syndrome, p38MAPK, ERK Received: August 29, 2016 Accepted: November 08, Published: December 27,...
Senior medical students feel unprepared for surgical procedures and care surgery patients when they begin their internship. This study sought to introduce evaluate a boot camp training senior students.A 44-h program of lectures on clinical practice simulation, anatomical dissections, simulated operation cadavers was designed, implemented, evaluated during the 2018 2019 academic year. A self-administered questionnaire used assess students' perceptions content, delivery, self-confidence. The...
Health care maldistribution is a long-term problem in China. Telemedicine an efficient way to deliver medical resources remote areas; however, there are few studies on the effectiveness and challenges providing health from rural urban areas China.The objective was describe of telemedicine for Guangzhou Guangdong Province.We designed surveys conducted them immediately after consultation 2-4 weeks later. Data were collected June 2015 May 2016 including patients' demographic features, patient...
Medical students' motivation and study strategies are crucial in determining academic performance. This aimed to assess the learning of medical students as well their association with performance anatomy examinations. The Motivated Strategies for Learning Questionnaire, two focus group discussions, current cumulative grade point average (cGPA) were used. Generally, strongly felt that is fundamental practice medicine surgery. result was consistent high task value scores 5.99 ± 1.25. They also...
Bisphenol-A (BPA) is commonly suspected to act as an endocrine disruptor, thus it important detect BPA residues in water and food samples. An indirect competitive ELISA (ic-ELISA) method was developed this study based on synthesis of a poly-L-lysine (PLL)–hapten conjugate coating antigen. The performance the PLL–4,4-bis(4-hydroxyphenol) valeric acid (BVA) immunoassay studied. established showed that PLL–BVA coated format could improve sensitivity ic-ELISA. limit detection 0.5 ng mL−1. IC50...
There is a lack of large-scale epidemiological data on the clinical practice enteral nutrition (EN) feeding in China. This study aimed to provide such Chinese hospitals and investigate factors associated with EN delivery.This cross-sectional was launched 118 intensive care units (ICUs) 116 mainland conducted April 26, 2017. At 00:00 all patients these ICUs were included. Demographic variables 25 obtained. The dates hospitalization, ICU admission initiation reviewed. outcome status 28 days...
Neuropathic pain caused by traumatic neuromas is an extremely intractable clinical problem. Disorderly scar tissue accumulation and irregular immature axon regeneration around the injury site mainly contribute to painful neuroma formation. Therefore, successfully preventing formation requires effective inhibition of disorderly tissue. Considering that chondroitin sulfate proteoglycans (CSPGs) can act on growth cone effectively inhibit regeneration, authors designed manufactured a...
Background: Urine output (UO) is an essential criterion of the Kidney Disease Improving Global Outcomes (KDIGO) definition and classification system for acute kidney injury (AKI), which diagnostic value has not been extensively studied. We aimed to determine whether AKI based on KDIGO UO criteria (KDIGOUO) could improve prognostic accuracy, compared with serum creatinine (KDIGOSCr). Methods: conducted a secondary analysis database previous study by China Critical Care Clinical Trial Group...
3-Hydroxycoumarin (3-HC) was designed, synthesized, and tested as a matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analyses of variety synthetic oligodeoxynucleotides ranging long from three to 70 bases. Using the solution 3-HC dissolved in mixed solvent acetone diammonium hydrogen citrate, DNA segments over range 800 Da 6900 were isotopically resolved with high signal-to-noise (S/N) ratio. The individual isotopic molecular ion peaks...
Abstract Postgraduate fellowship training programs are expanding at Chinese universities. This growing cadre of advanced trainees calls for the development new learning and models wherein postgraduate fellows have an ample opportunity to teach more junior learners, thereby their own knowledge base competitiveness future employment. Educational reform Sun Yat‐Sen University has recently allowed act as teaching assistants undergraduate anatomy courses. model is common in western countries but...
To estimate the prevalence and incidence of needlestick injuries associated with insulin injection among nurses working in hospitals China to quantify direct healthcare costs injection-related injuries.We conducted a large online survey hospital from 31 provinces, municipal cities, autonomous regions October 2016 February 2017. The covered wide range questions, including geographical location, years experience, practice, number past 12 months, interventions for injuries, treatment costs. We...