Lin Han

ORCID: 0000-0003-1441-0847
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About
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Research Areas
  • Clinical Nutrition and Gastroenterology
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Nutrition and Health in Aging
  • Machine Learning in Healthcare
  • Intensive Care Unit Cognitive Disorders
  • Sepsis Diagnosis and Treatment
  • Artificial Intelligence in Healthcare and Education
  • Respiratory viral infections research
  • Anesthesia and Sedative Agents
  • Pneumonia and Respiratory Infections
  • Anesthesia and Neurotoxicity Research
  • Pelvic and Acetabular Injuries
  • Spinal Fractures and Fixation Techniques
  • Traumatic Brain Injury Research
  • Cerebral Venous Sinus Thrombosis
  • Child Nutrition and Feeding Issues
  • Enhanced Recovery After Surgery
  • Nosocomial Infections in ICU
  • Neurosurgical Procedures and Complications

The People's Hospital of Guangxi Zhuang Autonomous Region
2021-2024

Guangxi Zhuang Autonomous Region Health and Family Planning
2024

Digital China Health (China)
2021-2022

The Eighth Hospital of Xi'an
2019

Abstract Background Previous cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain effects guideline implementation on patient-centered outcomes. Methods We conducted a multicenter, cluster-randomized, parallel-controlled trial intensive care units (ICUs) across China. developed...

10.1186/s13054-022-03921-5 article EN cc-by Critical Care 2022-02-16

For patients with pneumonia, the rapid detection of pathogens is still a major global problem in clinical practice because traditional diagnostic techniques for infection are time-consuming and insensitive. Metagenomic next-generation sequencing (mNGS) novel technique that has potential to improve pathogen diagnosis. This study aimed investigate microbiological ability mNGS compared conventional culture determine optimal time test pneumonia.

10.1186/s12879-024-10108-6 article EN cc-by-nc-nd BMC Infectious Diseases 2024-11-02

<title>Abstract</title> <bold>Background</bold>: For patients with pneumonia, rapid detection of pathogens is still a major global problem in clinical practice because traditional diagnostic techniques for infection are time-consuming and insensitive. Metagenomic next-generation sequencing (mNGS) novel technique that has the potential to improve pathogen diagnosis. In this study, we aimed explore microbiological ability mNGS compared conventional culture pneumonia best opportunityto test....

10.21203/rs.3.rs-4175027/v1 preprint EN cc-by Research Square (Research Square) 2024-04-09

To investigate the impact of goal directed analgesia on outcome patients with mechanical ventilation in intensive care unit.A total 126 who needed were recruited.With a method before and after paired comparison, they divided into two group: (1) empirical administration or control group; (2) based critical-care pain observation tool (CPOT). Compared group, was applied, consumption midazolam significantly dropped from (368.47±27.41) mg to (151.27±29.31) mg(P<0.05), whereas dexmedetomidine...

10.3760/cma.j.issn.0578-1426.2017.11.014 article EN PubMed 2017-11-01

Objective To investigate the risk factors associated with post traumatic cerebral infarction (PTCI) after craniotomy hematoma evacuation for severe brain injury (sTBI) so as to provide clinical reference early prevention of postoperative PTCI. Methods A retrospective case control study was conducted analyze data 558 sTBI patients who received admitted Changsha Hospital Traditional Chinese Medicine from October 2006 June 2016. There were 340 males and 218 females, aged 15-71 years, an...

10.3760/cma.j.issn.1001-8050.2019.01.011 article EN 2019-01-15

Objective To investigate the effect of appropriate hyperventilation therapy based on transcranial doppler (TCD) monitoring in patients with severe traumatic brain injury (sTBI). Methods Totally 59 sTBI were divided into control group (30 cases) and experimental (29 randomly. Patients treated hyperventilation, received mild ventilation according to cerebral vasospasm (CVS) monitored by TCD. The blood flow mean velocity (Vm) variation Vm (ΔVm) before after treatment middle artery (MCA)...

10.3877/cma.j.issn.1674-6880.2019.05.004 article EN Chin J Crit Care Med(Electronic Edition) 2019-10-01

Background: Equipoise exists regarding the implementation of evidence-based guidelines for nutritional therapy in critical illness because some previous cluster-randomised controlled trials (cRCTs) demonstrate patient benefits whilst others do not. We aimed to resolve this issue by initiating an appropriately powered cRCT assess whether active guideline nutrition could reduce mortality.Methods: did a multicentre, cluster-randomised, parallel-controlled trial 97 intensive care units (ICUs)...

10.2139/ssrn.3792190 article EN SSRN Electronic Journal 2021-01-01

<sec> <title>BACKGROUND</title> Modern clinical care in intensive units is full of rich data, and machine learning has great potential to support decision-making. The development intelligent learning–based decision systems facing opportunities challenges. Clinical may directly help clinicians accurately diagnose, predict outcomes, identify risk events, or decide treatments at the point care. </sec> <title>OBJECTIVE</title> We aimed review research application learning–enabled studies...

10.2196/preprints.28781 preprint EN 2021-03-15
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