A5101581901- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Pancreatitis Pathology and Treatment
- Sepsis Diagnosis and Treatment
- Dermatological and COVID-19 studies
- Clinical Nutrition and Gastroenterology
- COVID-19 and healthcare impacts
- COVID-19 and Mental Health
- Diabetes and associated disorders
- Nutrition and Health in Aging
- Diabetes Management and Research
- Respiratory Support and Mechanisms
- Pancreatic and Hepatic Oncology Research
- Metabolism, Diabetes, and Cancer
- Inflammatory Biomarkers in Disease Prognosis
- Climate Change and Health Impacts
- Abdominal Surgery and Complications
- SARS-CoV-2 and COVID-19 Research
- Renal function and acid-base balance
- Enhanced Recovery After Surgery
- Liver Disease Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Adipokines, Inflammation, and Metabolic Diseases
- Drug-Induced Ocular Toxicity
- Child Nutrition and Feeding Issues
Huazhong University of Science and Technology
2020-2025
Tongji Hospital
2020-2025
Second Xiangya Hospital of Central South University
2018-2023
Central South University
2018-2023
Health Commission of Anhui Province
2023
Zero to Three
2018
Abstract Background Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients diagnosed as mild early may progress to severe cases. However, it is difficult distinguish these in the stage. The present study aimed describe clinical characteristics patients, analyze related factors, and explore predictive markers aggravation. Methods laboratory data nonsevere adult COVID-19 Changsha, China, were collected analyzed on admission. A logistic regression model was...
Abstract Background The purpose of the study is to describe blood lipid levels patients diagnosed with coronavirus disease 2019 (COVID-19) and analyze correlation between prognosis COVID-19 patients. Methods In clinical retrospective analysis, a total 228 adults infected were enrolled January 17, 2020 March 14, 2020, in Changsha, China. One thousand one hundred forty healthy participants matched age gender used as control. Median interquartile range Mann-Whitney test adopted data....
Background Coronavirus disease 2019 (COVID-19) has been shown to affect almost every organ throughout the body. However, it is not clear whether thyroid gland impaired in COVID-19 patients. Euthyroid sick syndrome (ESS) usually associated with severity and deterioration prognosis critical illness. In this study, function of patients was assessed factors outcomes were analyzed determine potential predictive value ESS. Methods Clinical laboratory data or without ESS Changsha, China, collected...
Abstract Importance Coronavirus disease 2019 (COVID-19) is a pandemic with no specific drugs and high mortality. The most urgent thing to find effective treatments. Objective To determine whether hydroxychloroquine application may be associated decreased risk of death in critically ill COVID-19 patients what potential mechanism. Design, Setting Patients This retrospective study included all 568 who were confirmed by pathogen laboratory tests despite antiviral treatment had severe acute...
Abstract Background Previous cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain effects guideline implementation on patient-centered outcomes. Methods We conducted a multicenter, cluster-randomized, parallel-controlled trial intensive care units (ICUs) across China. developed...
Aim: The aim of the study was to describe clinical characteristics patients with or without respiratory alkalosis, and analyze relationship alkalosis outcome adult coronavirus disease 2019 (COVID-19) patients. Methods: Clinical laboratory data COVID-19 in a single center China, were retrospectively collected analyzed. Kaplan-Meier (KM) curve cox regression adopted association between prognosis Results: Of 230 patients, 66 (28.7%) had on admission. median age 53 years old (range, 21–84...
Diabetes mellitus (DM) is one of the most common comorbidities in patients with coronavirus disease (COVID-19). We aim to summarize clinical features DM COVID-19 and find out potential factors associated severe disease.In this retrospective, single-center study, medical records Changsha, Hunan, China, from January 21, 2020, February 19, were reviewed. Epidemiological information, features, outcomes compared between admitted intensive care unit (ICU) or not.A total 241 confirmed enrolled,...
Abstract This study aims to evaluate the effect of non‐alcoholic fatty liver disease (NAFLD) on susceptibility and consequences coronavirus 2019 (COVID‐19). We retrospectively collected data from 218 adult COVID‐19 patients who showed no evidence excessive alcohol consumption underwent abdominal ultrasound examinations. Of these patients, 39.4% had been diagnosed with NAFLD, which indicates a much higher prevalence NAFLD than that reported in general population. Significantly elevated white...
Abstract The coronavirus disease (COVID-19) pandemic has continued for 5 years. Sporadic cases continue to occur in different locations. Type 2 diabetes mellitus (T2DM) is associated with a high risk of poor prognosis patients COVID-19. Successful control blood glucose levels can effectively decrease the risks severe infections and mortality. However, effects treatments were reported differently even adversely. This retrospective study included 4,922 who have been diagnosed as COVID-19 T2DM...
Objective Association of angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) use with coronavirus disease 2019 (COVID-19) remains controversial. We aimed to investigate the impact ACEI/ARB on all-cause mortality in severe COVID-19 patients hypertension. Methods enrolled 650 from Changsha and Wuhan city between 17 January 2020 8 March 2020. Demographic, clinical characteristics, outcomes were collected. Multivariable analysis propensity-score matching...
Coronavirus disease 2019 (COVID-19) pandemic has caused substantial threats to people's physical health and lives, claiming the lives of over 6 million people worldwide. Although mortality rate COVID-19 is very low, many survivors may have different degrees various sequelae. Previous studies shown that pulmonary fibrosis (PF) were common on discharged patients, PF itself a poor prognostic factor.227 hospitalized patients' clinical laboratory data from first 15 days following admission...
Abstract Despite the progressive decline in virulence of novel coronavirus, there has been no corresponding reduction its associated hospital mortality. Our aim was to redefine an accurate predictor mortality risk COVID-19 patients, enabling effective management and resource allocation. We conducted a retrospective analysis 2917 adult Chinese patients diagnosed with who were admitted our during two waves epidemics, involving Beta Omicron variants. Upon admission, NT-proBNP levels measured,...
Aim: Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients did not show fever. However, the difference between clinical characteristics fevered and non-fevered is still unclear. The aim present study was to describe these analyze predictors for severe events adult COVID-19 patients. Methods: laboratory data in Changsha, China, were collected analyzed. Logistic regression analysis Receiver Operating Characteristic Curve (ROC Curve) adopted risk factors...
OBJECTIVES To investigate the clinical characteristics and risk factors for severe events of coronavirus disease 2019 (COVID-19) in elderly patients. METHODS Retrospective analysis was performed on data all COVID- 19 patients treated Changsha Public Health Treatment Center from January 17, 2020 to March 15, 2020, which included basic diseases, symptoms, test results, other characteristics, prognostic indicators such as severity illness, length hospital stay, virus shedding time mortality...
Coronavirus disease 2019 (COVID-19) emerged as a global pandemic and resulted in significantly high death toll. Therefore, there is an urgent need to find potential biomarker related the severity that can facilitate early-stage intervention.In present study, we collected 242 laboratory-confirmed COVID-19-infected patients. The patients were grouped according alveolar arterial oxygen tension difference (PA-aO2) value of COVID-19 infection after admission.Among COVID-19- infected patients, 155...
Abstract Background Inflammation plays an important role in progression of the various viral pneumonia containing COVID-19, severe inflammatory responses could lead to imbalance immune response. The purpose this study was explore possibility white blood count, neutrophil percentage, neutrophil-to-monocyte ratio (NMR) and neutrophil-to-lymphocyte (NLR) at admission reflect clinical severity patients with COVID‐19. Methods Clinical laboratory data adult COVID-19 Changsha, China, were collected...
Abstract Background COVID-19 pandemic has become a serious global public health problem. Although the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor type 1 blockers (ARBs) been recommended in patients with cardiovascular diseases (CVDs), according to results some small-sample retrospective analyses; however, there is still lack sufficient evidence validate their efficacy. This multicenter study investigated whether ACEI/ARB administration was beneficial...