Yunlin Song

ORCID: 0000-0003-2073-7328
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Research Areas
  • Nutrition and Health in Aging
  • Clinical Nutrition and Gastroenterology
  • Barrier Structure and Function Studies
  • Enhanced Recovery After Surgery
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Neurotoxicity Research
  • Hemodynamic Monitoring and Therapy
  • Cancer-related molecular mechanisms research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Blood Coagulation and Thrombosis Mechanisms
  • Respiratory Support and Mechanisms
  • Lipid metabolism and disorders
  • Angiogenesis and VEGF in Cancer
  • Atrial Fibrillation Management and Outcomes
  • Mycobacterium research and diagnosis
  • vaccines and immunoinformatics approaches
  • Child Nutrition and Feeding Issues
  • Tuberculosis Research and Epidemiology
  • MicroRNA in disease regulation
  • Mechanical Circulatory Support Devices
  • Sirtuins and Resveratrol in Medicine
  • Esophageal and GI Pathology
  • Circular RNAs in diseases
  • Airway Management and Intubation Techniques

Xinjiang Medical University
2013-2024

First Affiliated Hospital of Xinjiang Medical University
2013-2024

Abstract Background Previous cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain effects guideline implementation on patient-centered outcomes. Methods We conducted a multicenter, cluster-randomized, parallel-controlled trial intensive care units (ICUs) across China. developed...

10.1186/s13054-022-03921-5 article EN cc-by Critical Care 2022-02-16

Endothelial progenitor cells (EPCs) originate from the bone marrow and can be classified as either early or late EPCs. The focus of this study was on EPCs, they play an important role in angiogenesis vascular proliferation. Evidence suggests that inflammatory oxidative changes increase EPC apoptosis. Of note, tumor necrosis factor-α (TNF-α) is a contributing risk factor to development atherosclerosis plays key both mediator inducer apoptosis endothelial cells. Additionally, member sirtuin...

10.3892/ijmm.2014.1740 article EN International Journal of Molecular Medicine 2014-04-09

Abstract Objective This study aimed to identify the potential inflammatory molecular biomarkers that could be utilized for early prediction of different subtypes tuberculosis (TB) in adults. Methods Plasma samples were obtained from a cohort adults diagnosed with 48 cases active TB, including drug-susceptible TB (S-TB, n = 28), multidrug-resistant (R-TB, 20), latent infection (LTBI, as well control group healthy individuals without any (HC, 20). The expression level 92 inflammatory-related...

10.1007/s00011-025-02020-9 article EN cc-by Inflammation Research 2025-04-01

There is a lack of large-scale epidemiological data on the clinical practice enteral nutrition (EN) feeding in China. This study aimed to provide such Chinese hospitals and investigate factors associated with EN delivery.This cross-sectional was launched 118 intensive care units (ICUs) 116 mainland conducted April 26, 2017. At 00:00 all patients these ICUs were included. Demographic variables 25 obtained. The dates hospitalization, ICU admission initiation reviewed. outcome status 28 days...

10.1186/s13054-018-2159-x article EN cc-by Critical Care 2018-09-20

MicroRNA‑34a (miR‑34a) is a direct target of p53 and was reported to induce cell cycle arrest, apoptosis senescence. Inhibition the NAD‑dependent deacetylase sirtuin‑1 (SIRT1) by miR‑34a leads an increase in acetylated p53, which promotes apoptosis. B‑cell lymphoma 2 (Bcl‑2) also involved apoptosis, originally characterized with respect its role controlling outer mitochondrial membrane integrity. The effect PC12 cells has not yet been reported. In present study, it hypothesized that Bcl‑2...

10.3892/mmr.2015.4185 article EN cc-by-nc-nd Molecular Medicine Reports 2015-08-05

There were controversial opinions on the use of bivalirudin versus heparin for anticoagulant therapy in extracorporeal membrane oxygenation. The aim our present study is to evaluate efficacy and safety maintenance systemic anticoagulation during adult veno-venous oxygenation (V-V ECMO).Adult patients who received V-V ECMO support center between February 2018and 2022 retrospectively recruited. We analyzed their time, platelet count, coagulation indicators, blood product infusion volume,...

10.1177/03913988221148763 article EN The International Journal of Artificial Organs 2023-01-04

Patients with craniocerebral trauma often have intestinal mucosal dysfunction, and the claudin1 protein plays an important role in function. Our previous work has shown that expression of microRNA-155 (miR-155) peripheral blood patients is decreased. Animal experiments also suggest miR-155 increased mucosa mice brain injury We recruited 56 samples (35 traumatic [TBI] 21 without history head trauma) to detect on regulation by quantitative polymerase chain reaction, reverse transcriptase so...

10.1016/j.transproceed.2019.08.042 article EN cc-by-nc-nd Transplantation Proceedings 2019-12-01

The vascular injury induced by central venous catheter (CVC) indwelling is the basis for occurrence and development of CVC-related complications, such as phlebitis, thrombosis, catheter-related infections. Focal adhesion kinase (FAK) FAK-protein B (AKT) signaling pathway are great significance in tissue repair after trauma. Here, we investigated role mechanism FAK inhibitor (1,2,4,5-phenyltetramine tetrahydrochloride (Y15)) oxidative damage caused CVC. EA.hy926 cells were divided into...

10.1155/2021/6685493 article EN cc-by BioMed Research International 2021-03-01

<title>Abstract</title> <bold>Objective</bold> The objective of this study was to identif<underline>y the </underline>potential inflammatory molecular biomarkers that could be utilized for early prediction different subtype tuberculosis (TB) in adults. <bold>Methods</bold> Plasma samples were obtained from a cohort adults diagnosed with 48 cases <bold>active (</bold>TB), including drug susceptible TB (DS-TB, n=28), multidrug resistant (MDR-TB, n=20), latent infection (LTBI, as well control...

10.21203/rs.3.rs-4876065/v1 preprint EN cc-by Research Square (Research Square) 2024-10-17

To evaluate the efficacy and safety of automatic variable flow rate (AutoFlow) for volume control ventilation through monitoring number ventilator alarm.Forty-eight adult patients receiving Drager Evita 4 with an expectation more than 2 days duration were divided into two groups by randomly digital methods, each n=24. The in group received routinely mode synchronized intermittent mandatory (SIMV), others observation given SIMV assist AutoFlow. midazolam fentanyl was to retain Ramsay score...

10.3760/cma.j.issn.2095-4352.2013.06.003 article EN PubMed 2013-06-01

Background: Equipoise exists regarding the implementation of evidence-based guidelines for nutritional therapy in critical illness because some previous cluster-randomised controlled trials (cRCTs) demonstrate patient benefits whilst others do not. We aimed to resolve this issue by initiating an appropriately powered cRCT assess whether active guideline nutrition could reduce mortality.Methods: did a multicentre, cluster-randomised, parallel-controlled trial 97 intensive care units (ICUs)...

10.2139/ssrn.3792190 article EN SSRN Electronic Journal 2021-01-01
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