Yuanyi Zhang

ORCID: 0009-0006-6312-8812
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About
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Research Areas
  • Osteoarthritis Treatment and Mechanisms
  • Knee injuries and reconstruction techniques
  • Frailty in Older Adults
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Meat and Animal Product Quality
  • Nutrition and Health in Aging
  • Respiratory and Cough-Related Research
  • Monoclonal and Polyclonal Antibodies Research
  • FOXO transcription factor regulation
  • Asthma and respiratory diseases
  • Cultural and Historical Studies
  • Advanced Chemical Sensor Technologies
  • Musculoskeletal synovial abnormalities and treatments
  • Protein purification and stability
  • Extracellular vesicles in disease
  • Circular RNAs in diseases
  • Atrial Fibrillation Management and Outcomes
  • Cell Adhesion Molecules Research
  • Polyamine Metabolism and Applications
  • Thermal Regulation in Medicine
  • Ubiquitin and proteasome pathways
  • Chromatography in Natural Products
  • Drug-Induced Adverse Reactions
  • Animal Nutrition and Physiology
  • Per- and polyfluoroalkyl substances research

The University of Texas Medical Branch at Galveston
2022-2025

First Affiliated Hospital of Zhengzhou University
2023-2024

First Affiliated Hospital of Anhui Medical University
2023-2024

Anhui Medical University
2023-2024

Zhaoqing University
2022-2024

Zhejiang University
2024

WuXi AppTec (China)
2022

University of South China
2022

Southwest Petroleum University
2022

Shanghai Ocean University
2019

This study investigates the potential use of circulating extracellular vesicles' (EVs) DNA and protein content as biomarkers for traumatic brain injury (TBI) in a mouse model. Despite an overall decrease EVs count during acute phase, there was increased presence exosomes (CD63

10.1016/j.isci.2024.108932 article EN cc-by-nc-nd iScience 2024-01-21

A total of 20 healthy white × landrace sows were evenly and randomly divided into two groups, fed basal diets unsupplemented or supplemented with 500 g/t Meriden-Stim® from day 100 gestation until 21 lactation. Serum fecal samples collected the on final for subsequent analysis. Compared to control group, there no significant differences in sows’ performances; however, an increase was observed piglets’ weight at weaning (p = 0.08). Moreover, oregano essential oil (OEO) significantly reduced...

10.3390/ani14050753 article EN cc-by Animals 2024-02-28

Introduction The management of nutritional risk has garnered significant attention in individuals diagnosed with acute exacerbation chronic obstructive pulmonary disease (AECOPD) due to the high prevalence malnutrition and its correlation unfavorable outcomes. While numerous rating scales exist assist assessment for both clinical research purposes, there is considerable variability selection based on characteristics study participants design. objective this was examine efficacy Geriatric...

10.3389/fnut.2024.1365462 article EN cc-by Frontiers in Nutrition 2024-08-09

Activation of EGFR is a major risk factor for non-small cell lung cancer (NSCLC). Understanding the molecular events promoting activation can help us gain more insights into progression NSCLC. In this study, we demonstrate that collagen type VIII alpha 1 chain (COL8A1), an extracellular matrix component, was overexpressed in NSCLC cells, knockdown COL8A1 suppressed growth, cycle progression, and migration, induced apoptosis. While overexpression promoted proliferation inhibited addition,...

10.3389/fonc.2022.707525 article EN cc-by Frontiers in Oncology 2022-02-24

There is a significant amount of literature focusing on racial inequities in utilization rates and intraoperative complications cataract surgery. Unfortunately, little known about disparities regarding the timeline surgery intraocular lens (IOL) selection. This study investigated whether black patients have different preoperative postoperative IOL selection than white patients.

10.1167/tvst.12.11.20 article EN cc-by-nc-nd Translational Vision Science & Technology 2023-11-17

Osteosarcoma is a highly metastatic malignant bone tumor, necessitating the development of new treatments to target its metastasis. Recent studies have revealed significance VAMP8 in regulating various signaling pathways types cancer. However, specific functional role osteosarcoma progression remains unclear. In this study, we observed significant downregulation cells and tissues. Low levels tissues were associated with patients' poor prognosis. inhibited migration invasion capability cells....

10.1080/15384047.2023.2230641 article EN cc-by Cancer Biology & Therapy 2023-07-05

Objective Per- and polyfluoroalkyl substances (PFAS) alter immune function increasing infectious diseases risk. We examined the relationship between PFAS chlamydia. Methods A total of 3965 nonpregnant adults ages 18–39 years from National Nutrition Examination Survey 2003–2016 cycles were included. Poisson regression with robust error variance estimated prevalence ratio 95% confidence intervals for association g computation model was used to examine mixtures Results In adjusted age...

10.1097/jom.0000000000003151 article EN Journal of Occupational and Environmental Medicine 2024-05-16

Abstract Background This study investigates the potential of novel meniscal parameters as predictive factors for incident radiographic knee osteoarthritis (ROA) over a span four years, part Osteoarthritis Initiative (OAI) study. Objectives Quantitative measurements alteration could serve predictors OA’s occurrence and progression. Methods materials A nested matched case-control design was used to select participants from OAI Case knees ( n = 178) were defined those with ROA (Kellgren...

10.1186/s12891-024-07706-5 article EN cc-by BMC Musculoskeletal Disorders 2024-08-06

Abstract Background Sexually transmitted infections (STIs) have recently been linked to hypertensive disorders of pregnancy (HDP). However, the impact Neisseria gonorrhoeae on risk HDP is not well understood. This study determined gonorrhea and coinfection other adverse outcomes in a population with high screening rate presumed treatment. Methods retrospective included 29 821 singleton births between 2016 2021. The STI testing results, demographic variables, were identified from electronic...

10.1093/ofid/ofad220 article EN cc-by-nc-nd Open Forum Infectious Diseases 2023-04-21

In cervical cancer (CC), the efficacy of chemotherapy is often hindered by development paclitaxel (PTX) resistance, even in patients who initially responded to chemotherapy.However, mechanisms underlying PTX resistance CC remain unclear.In this study, we uncover a unique role played CENPU (centromeric protein U, also known as PBIP1/KLIP1/CENP-50/MLF1IP) association with cells.First, established paclitaxel-resistant cell lines from Hela and SiHa cells (designated Hela/PTX SiHa/PTX) confirmed...

10.22514/ejgo.2024.014 article EN European Journal of Gynaecological Oncology 2024-01-01

Abstract The potential impact of birthweight on adult lung function has been postulated, yet the precise nature this association in later life remains inconclusive. This study involved extracting data from a total 201,615 individuals UK Biobank dataset. To identify group differences based subgroups, propensity score matching and pairwise t-test were conducted. was established using linear regression, gradually adjusting for variables. Additionally, subgroup analyses conducted to investigate...

10.21203/rs.3.rs-4168941/v1 preprint EN cc-by Research Square (Research Square) 2024-04-11

Abstract Background : To determine whether novel meniscus parameters are predictive of incident radiographic knee osteoarthritis (ROA) over four years in the Osteoarthritis Initiative (OAI) study. Methods Participants were extracted from 178 knees (from 176 patients ) with ROA (Kellgren Lawrence Grade (KLG) 0 or 1 at baseline (BL), developing KLG 2 greater by year 4) matched one-to-one gender, age and status control patients) not ROA. Novel meniscal measured on coronal T2-weighted turbo spin...

10.21203/rs.3.rs-3015796/v1 preprint EN cc-by Research Square (Research Square) 2023-06-07

Abstract Prognostic Nutritional Index (PNI) in identifying malnutrition and predicting prognosis AECOPD patients. Design: Retrospective cohort study Setting participants: The research encompassed a of 839 individuals aged 60 years above, who were admitted to the First Affiliated Hospital Zhengzhou University during period spanning January 2022 December 2022, owing acute exacerbation chronic obstructive pulmonary disease (AECOPD). Methods: From consecutive inclusion patients was conducted....

10.21203/rs.3.rs-3280965/v1 preprint EN cc-by Research Square (Research Square) 2023-09-12

Abstract Background: This study investigates the potential of novel meniscal parameters as predictive factors for incident radiographic knee osteoarthritis (ROA) over a span four years, part Osteoarthritis Initiative (OAI) study. Methods: A subset 178 knees (from 176 patients ) from OAI study, with ROA (Kellgren Lawrence Grade (KLG) 0 or 1 at baseline (BL), evolving into KLG 2 above by year 4), were matched gender, age and status on one-to-one basis control patients) that did not develop...

10.21203/rs.3.rs-3015796/v2 preprint EN cc-by Research Square (Research Square) 2023-11-14

Objective To investigate the clinical effects and safety of agomelatine in treatment anxiety depression. Methods A total 200 patients with depression admitted to Sixth People’s Hospital Datong from March 2016 2018 were selected. The divided into group according their specific diagnoses, 100 cases each group. All treated for 8 weeks. adverse reactions two observed compared. Results The groups completed weeks successfully. During period, there no abnormal circumstances such as...

10.3760/cma.j.issn.1674-4756.2019.18.035 article EN Central Plains Medical Journal 2019-09-25

From the perspective of category conversion theory, this paper studies post-translation editing neural network translation by taking English version To Live translated Google as an example. The study found that Goggle can basically complete language conversion, but it applies word-to-word method to most non-linguistic making confusing. Therefore, in post-editing, translator should consider cultural background target and select prototype line with cognition readers; process vacancy methods...

10.25236/fsst.2022.040308 article EN The Frontiers of Society Science and Technology 2022-01-01
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