A5064533925- Diabetes Management and Research
- Pancreatic function and diabetes
- Mesenchymal stem cell research
- Diabetes and associated disorders
- Thyroid Disorders and Treatments
- Hormonal Regulation and Hypertension
- COVID-19 Clinical Research Studies
- Vitamin D Research Studies
- Ion Transport and Channel Regulation
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Thyroid Cancer Diagnosis and Treatment
- Renin-Angiotensin System Studies
- Pancreatitis Pathology and Treatment
Shanghai Public Health Clinical Center
2022-2024
Zero to Three
2023
Nanjing Drum Tower Hospital
2020-2022
Abstract Background The preservation or restoration of β cell function in type 1 diabetes (T1D) remains as an attractive and challengeable therapeutic target. Mesenchymal stromal cells (MSCs) are multipotent with high capacity immunoregulation, which emerged a promising cell-based therapy for many immune disorders. objective this study was to examine the efficacy safety one repeated transplantation allogeneic MSCs individuals T1D. Methods This nonrandomized, open-label, parallel-armed...
Abstract Background Although type 1 diabetes (T1D) is typically described as a T cell-mediated autoimmune disease, increasing evidence for role of B cells has emerged. However, the pivotal disease-relevant cell subset and its contribution to islet autoimmunity remain elusive. Methods The frequencies phenotypic characteristics circulating subsets were analyzed using flow cytometry in individuals with new-onset T1D, long-term 2 diabetes, nondiabetic controls, also prospective cohort patients...
Purpose Through describing the confusing misdiagnosis process of Liddle syndrome, we try to reveal importance accurate aldosterone-renin detection and a genetic test for syndrome.Methods We found family hypertension hypokalaemia with proband 21-year-old female who had been misdiagnosed as primary aldosteronism (PA). She presented high aldosterone low renin levels. Aldosterone is not suppressed in saline infusion captopril challenge test. However, treatment standard dose spironolactone has no...
Objective This study aims to examine the thyroid hormone profile and its association with severe coronavirus disease 2019 (COVID-19) in patients infected by acute respiratory syndrome 2 (SARS-CoV-2). Methods retrospective cohort enrolled admitted a tertiary hospital due SARS-CoV-2 infection between February 18 May 18, 2022. Clinical data were collected retrospectively from electronic medical record system. Based on function, divided into five groups: normal, non-thyroid illness (NTIS),...
Abstract Background: The preservation or restoration of b-cell function in type 1 diabetes (T1D) remains as an attractive and challengeable therapeutic target. Mesenchymal stromal cells (MSCs) are multipotent with high capacity immunoregulation, which emerged a promising cell-based therapy for many immune disorders. objective this study was to examine the efficacy safety one repeated transplantation allogeneic MSCs individuals T1D. Methods: This nonrandomized, open-label, parallel-armed...
Abstract Aims/Introduction Serum amyloid A (SAA) is an acute phase reactive protein that plays a vital role in the early diagnosis, risk prediction, efficacy observation and prognosis evaluation of infectious diseases. This study aimed to assess association between SAA levels patients with coronavirus disease 2019 (COVID‐19) diabetes. Materials Methods We carried out this retrospective cohort from March 2022 May 2022. The population was stratified by tertiles levels: low (<8.5 mg/L),...