A5065875183- Thermodynamic properties of mixtures
- Nonlinear Optical Materials Research
- Advanced Drug Delivery Systems
- Gas Sensing Nanomaterials and Sensors
- Chemical Thermodynamics and Molecular Structure
- Phytochemistry and biological activities of Ficus species
- Molecular Spectroscopy and Structure
- Lipid Membrane Structure and Behavior
- Immune Response and Inflammation
- Chemical and Physical Properties in Aqueous Solutions
- Polymer Science and PVC
- Advancements in Transdermal Drug Delivery
- Bacteriophages and microbial interactions
- Advanced Chemical Sensor Technologies
- Bacterial biofilms and quorum sensing
- Garlic and Onion Studies
- vaccines and immunoinformatics approaches
- Biodiesel Production and Applications
- Antimicrobial Peptides and Activities
- Antifungal resistance and susceptibility
- Systemic Sclerosis and Related Diseases
- SARS-CoV-2 and COVID-19 Research
- Antimicrobial Resistance in Staphylococcus
- ZnO doping and properties
- Analytical Chemistry and Sensors
Panjab University
2020-2025
University of Lucknow
2017-2022
In light of growing global challenge posed by antimicrobial resistance, it is very important to explore alternatives that can target pathogenic microorganisms. One such strategy involves the use peptides (AMPs) and Stigmurin one AMP present in Brazilian scorpion Tityus stigmurus which possesses antimicrobial, antiproliferative antiparasitic activity. The study commenced with successful synthesis characterization its analogues, designated S1 S2. Studies on analogues have demonstrated exhibit...
The emergence of multidrug-resistant microbes is a significant health concern posing constant need for new antimicrobials. Membrane-targeting antibiotics are promising candidates with reduced ability to develop resistance. In the present investigation, principal reason behind choosing cholic acid as crucial scaffold lies in fact that it has facially amphiphilic nature, which provides ample opportunity refine amphiphilicity by linking amino lysine. A total 16 novel amphipathic derivatives...
We report a promising strategy based on chitosan (CS) hydrogels and dual temperature- pH-responsive poly(N-isopropylacrylamide-co-methacrylic acid) (PNIPAM-co-MAA) microgels to facilitate release of model drug, moxifloxacin (MFX). In this protocol, first, the were prepared using free radical copolymerization method, subsequently, these carboxyl-group-rich soft particles incorporated inside hydrogel matrix an EDC-NHS amidation method. Interestingly, resulting microgel-embedded composites...
For the binary mixture of water and N, N-dimethylacetamide (DMA), observations have been done ultrasonic velocity (u), density (ρ), viscosity (η) refractive index (n) in excess whole composition range at various temperature. Deviation (Δu), intermolecular free length (LfE), acoustic impedance (ZE), molar volume (VmE), deviation refraction (ΔRm), (Δη) Gibbs' energy activation for viscous flow (ΔG*E) were used to investigate interactions present mixture. Derived parameters such as isoentropic...
The aim of the present study is to fabricate stable nanostructured lipid carriers (NLCs) using biocompatible excipients for encapsulation Methotrexate (MTX), a chemotherapeutic agent breast cancer treatment. MTX has restricted clinical applications owing its low solubility, non-specific targeting and adverse side effects. Glyceryl Monostearate (GMS) Miglyol 812 (MI1) were chosen as solid liquid lipids, respectively, fabrication NLCs, influence variation composition was investigated. prepared...
The present work dwells upon developing and assessing the efficacy of nanoemulsion (NEm) for Methotrexate (MTX) delivery. Herein, MTX-loaded NEm was prepared using ultrasonic nano emulsification method by exploiting biocompatible excipients such as α-Tocopherol, Miglyol 812, Tween 80, ethanol. Employing processes leads to preparation with smaller droplet sizes uniform distribution. physicochemical characterization transmission electron microscopy confirmed that blank possesses...