A5092576369- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- COVID-19 Clinical Research Studies
- Immune cells in cancer
- Innovation and Socioeconomic Development
- HIV Research and Treatment
- Immune Cell Function and Interaction
- CRISPR and Genetic Engineering
University of California, San Francisco
2023-2024
The mechanisms of postacute medical conditions and unexplained symptoms after SARS-CoV-2 infection [Long Covid (LC)] are incompletely understood. There is growing evidence that viral persistence, immune dysregulation, T cell dysfunction may play major roles. We performed whole-body positron emission tomography imaging in a well-characterized cohort 24 participants at time points ranging from 27 to 910 days acute using the radiopharmaceutical agent [
ABSTRACT The etiologic mechanisms of post-acute medical morbidities and unexplained symptoms (Long COVID) following SARS-CoV-2 infection are incompletely understood. There is growing evidence that viral persistence immune dysregulation may play a major role. We performed whole-body positron emission tomography (PET) imaging in cohort 24 participants at time points ranging from 27 to 910 days acute using novel radiopharmaceutical agent, [ 18 F]F-AraG, highly selective tracer allows for...
Purpose of review Durable HIV-1 remission has been reported in a person who received allogeneic stem cell transplants (SCTs) involving CCR5 Δ32/Δ32 donor cells. Much the reduction burden following SCT with or without cells inherently resistant to infection is likely due cytotoxic graft-versus-host effects on residual recipient immune Nonetheless, there growing momentum develop and implement therapies that lead durable long-term antiretroviral therapy (ART)-free need for SCT. Recent findings...