A5102965301- Organ Transplantation Techniques and Outcomes
- Renal Diseases and Glomerulopathies
- Renal and Vascular Pathologies
- Intensive Care Unit Cognitive Disorders
- COVID-19 Clinical Research Studies
- Renal Transplantation Outcomes and Treatments
- Head and Neck Anomalies
- Transplantation: Methods and Outcomes
- Long-Term Effects of COVID-19
- Vasculitis and related conditions
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Omental and Epiploic Conditions
- Fungal Biology and Applications
- Metabolism and Genetic Disorders
- HIV Research and Treatment
- Nephrotoxicity and Medicinal Plants
- Salivary Gland Tumors Diagnosis and Treatment
- Ginkgo biloba and Cashew Applications
- CNS Lymphoma Diagnosis and Treatment
- Skin Protection and Aging
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Dermatologic Treatments and Research
- Sinusitis and nasal conditions
- HIV-related health complications and treatments
- IgG4-Related and Inflammatory Diseases
University of California, San Francisco
2014-2024
Magyar Agrár- és Élettudományi Egyetem
2023
University of Pecs
2014-2016
Beth Israel Deaconess Medical Center
2014
National Institutes of Health
2014
University of Washington
2014
Memorial Sloan Kettering Cancer Center
2014
University of California, Los Angeles
2014
Massachusetts General Hospital
2014
Boston University
2014
The mechanisms of postacute medical conditions and unexplained symptoms after SARS-CoV-2 infection [Long Covid (LC)] are incompletely understood. There is growing evidence that viral persistence, immune dysregulation, T cell dysfunction may play major roles. We performed whole-body positron emission tomography imaging in a well-characterized cohort 24 participants at time points ranging from 27 to 910 days acute using the radiopharmaceutical agent [
ABSTRACT The etiologic mechanisms of post-acute medical morbidities and unexplained symptoms (Long COVID) following SARS-CoV-2 infection are incompletely understood. There is growing evidence that viral persistence immune dysregulation may play a major role. We performed whole-body positron emission tomography (PET) imaging in cohort 24 participants at time points ranging from 27 to 910 days acute using novel radiopharmaceutical agent, [ 18 F]F-AraG, highly selective tracer allows for...
Bone tissue regeneration is a major, worldwide medical need, and several strategies have been developed to support the of extensive bone defects, including stem cell based grafts. In addition application cells with high osteogenic potential, it important maintain proper blood flow in graft avoid inner necrosis. Mesenchymal (MSCs) may form both osteocytes endothelial cells; therefore we examined combined vitro differentiation capacities MSCs derived from adipose tissue, Wharton’s jelly,...
In this study, the disrupting effects of glyphosate (GLY), aminomethylphosphonic acid (AMPA), and three glyphosate-based herbicides (GBHs) on vitellogenesis in a non-concentration-dependent manner are reported for first time 120 h acute exposure zebrafish at environmentally relevant concentrations. GBHs commonly used worldwide weed control management. Due to their extensive application, they frequently occur aquatic ecosystems may affect various organisms. The active substance GLY its major...
Background. The role of the soluble urokinase plasminogen activator receptor (suPAR) in focal segmental glomerulosclerosis (FSGS) as circulating factor or a predictor recurrence after transplantation remains controversial. Previously published studies mice and isolated podocytes produced conflicting results on effect suPAR podocyte injury, effacement foot processes, proteinuria. These discordant were part due to diverse experimental designs different strains mice. aim our study was determine...
Abstract Background We investigated circulating levels of individual soluble urokinase plasminogen activation receptor (su PAR ) forms to determine if specific fragments su ( II ‐ III and (I) can better serve as clinical biomarkers for focal segmental glomerulosclerosis FSGS the risk recurrence after transplantation. Materials Methods Serum intact its cleaved were measured with two assays, ELISA TR FIA . Results in healthy controls significantly lower than those who had glomerular diseases...
Periodontal ligament stem cells (PDLSCs) provide an important source for tissue regeneration and may become especially useful in the formation of osteogenic seeds. PDLSCs can be cultured, expanded, differentiated vitro; thus, they applied long-term treatment defects dental regions. Here we studied numerous potential markers allowing selection human with a maximum differentiation potential. We followed expression ATP-binding cassette subfamily G member 2 (ABCG2) membrane transporter protein...
Long-term kidney transplant (KT) allograft outcomes have not improved as expected despite a better understanding of rejection and immunosuppression. Previous work had validated computed score, the tissue common module (tCRM), measured by amplification-based assessment 11 genes from formalin-fixed paraffin-embedded (FFPE) biopsy specimens, which allows for quantitative, unbiased immune injury. We applied tCRM in prospective trial 124 KT recipients, contrasted histology reads 2 independent...
Background. Although kidney transplantation (KT) has become the standard of care for people living with HIV (PLWH) suffering from renal failure, early experiences revealed unanticipated higher rejection rates than those observed in HIV− recipients. The cause increased acute (AR) PLWH was assessed by performing a transcriptomic analysis biopsy specimens, comparing HIV+ to Methods. An 68 (34 HIV+, 34 HIV−) formalin-fixed paraffin-embedded (FFPE) biopsies matched degree inflammation performed...
Purpose. Belatacept (Bela), a CD28/B7 co-stimulation pathway inhibitor, used as an alternative to calcineurin inhibitor (CNI)-based immunosuppression after renal transplantation, is associated with higher incidence of acute cellular rejection (ACR). Recent experimental data indicate that ACR in patients treated Bela might be mediated by alloreactive CD8 memory effector T cells low CD28 expression. Our study tested the hypotheses transplant biopsies on proportions CD4 and lymphocytes...
Quick and efficient protoplast isolation from Neurospora crassa.Quick crassa.
Introduction: Acute cellular rejection (ACR) can occur at any time following liver transplantation (LT); initial ACR within 6 months is most common and occurs in up to 70% of recipients, with approximately 20% patients experiencing one or more recurrent episodes. Chronic (CR) has been associated increasing numbers episodes some studies, the ultimate cause graft failure 15% LT recipients. We sought determine whether there were transcriptomic differences CR after LT. Methods: A total 38...