A5073447792- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- HIV Research and Treatment
- Intensive Care Unit Cognitive Disorders
- CRISPR and Genetic Engineering
- Microfinance and Financial Inclusion
- Innovation and Socioeconomic Development
- Thermal Regulation in Medicine
- Virus-based gene therapy research
- Inflammasome and immune disorders
- CAR-T cell therapy research
- Immune cells in cancer
- Immune Cell Function and Interaction
- HIV/AIDS drug development and treatment
University of California, San Francisco
2022-2024
San Francisco State University
2024
BACKGROUND. The presence and reactivation of chronic viral infections, such as EBV, CMV, HIV, have been proposed potential contributors to long COVID (LC), but studies in well-characterized postacute cohorts individuals with COVID-19 over a longer time course consistent current case definitions LC are limited.
The mechanisms of postacute medical conditions and unexplained symptoms after SARS-CoV-2 infection [Long Covid (LC)] are incompletely understood. There is growing evidence that viral persistence, immune dysregulation, T cell dysfunction may play major roles. We performed whole-body positron emission tomography imaging in a well-characterized cohort 24 participants at time points ranging from 27 to 910 days acute using the radiopharmaceutical agent [
ABSTRACT The etiologic mechanisms of post-acute medical morbidities and unexplained symptoms (Long COVID) following SARS-CoV-2 infection are incompletely understood. There is growing evidence that viral persistence immune dysregulation may play a major role. We performed whole-body positron emission tomography (PET) imaging in cohort 24 participants at time points ranging from 27 to 910 days acute using novel radiopharmaceutical agent, [ 18 F]F-AraG, highly selective tracer allows for...
The presence and reactivation of chronic viral infections such as Epstein-Barr virus (EBV), cytomegalovirus (CMV) human immunodeficiency (HIV) have been proposed potential contributors to Long COVID (LC), but studies in well-characterized post-acute cohorts individuals with COVID-19 over a longer time course consistent current case definitions LC are limited. In cohort 280 adults prior SARS-CoV-2 infection, we observed that symptoms fatigue neurocognitive dysfunction at median 4 months...
Purpose of review Durable HIV-1 remission has been reported in a person who received allogeneic stem cell transplants (SCTs) involving CCR5 Δ32/Δ32 donor cells. Much the reduction burden following SCT with or without cells inherently resistant to infection is likely due cytotoxic graft-versus-host effects on residual recipient immune Nonetheless, there growing momentum develop and implement therapies that lead durable long-term antiretroviral therapy (ART)-free need for SCT. Recent findings...
Abstract The associations between longitudinal dynamics and the breadth of SARS‐CoV‐2 neutralizing antibody (nAb) response with various Long COVID phenotypes before vaccination are not known. capacity antibodies to cross‐neutralize a variety viral variants may be associated ongoing pathology persistent symptoms. We measured cross‐neutralizing responses pre‐ post‐SARS‐CoV‐2 Omicron in participants infected early COVID‐19 pandemic, widespread rollout vaccines. Cross‐sectional regression models...
The associations between longitudinal dynamics and the breadth of SARS-CoV-2 neutralizing antibody response with various Long COVID (LC) phenotypes prior to vaccination are not known. capacity antibodies cross neutralize a variety viral variants may be associated ongoing pathology persistent symptoms.