A5103962634- Cardiac Arrhythmias and Treatments
- Ion channel regulation and function
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Pituitary Gland Disorders and Treatments
- Cardiac Fibrosis and Remodeling
- Transplantation: Methods and Outcomes
- Spaceflight effects on biology
- Nerve injury and regeneration
- Viral Infections and Immunology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Receptor Mechanisms and Signaling
- Lipid metabolism and disorders
- Nitric Oxide and Endothelin Effects
- Phytochemicals and Antioxidant Activities
- Adipose Tissue and Metabolism
- Adrenal and Paraganglionic Tumors
- ECG Monitoring and Analysis
- Genomics, phytochemicals, and oxidative stress
- Machine Learning in Materials Science
- Adenosine and Purinergic Signaling
- Cardiovascular Issues in Pregnancy
Weihai Municipal Hospital
2024
Shandong University
2024
Shenzhen Children's Hospital
2023
Zhongda Hospital Southeast University
2021
Jiangsu University
2021
Affiliated Hospital of Jiangsu University
2021
Tongde Hospital of Zhejiang Province
2018
Ocean University of China
2016
University of Copenhagen
2013
Danish National Research Foundation
2013
Hyperglycemia induces chronic inflammation and oxidative stress in cardiomyocyte, which are the main pathological changes of diabetic cardiomyopathy (DCM). Treatment aimed at these processes may be beneficial DCM. Phloretin (PHL), a promising natural product, has many pharmacological activities, such as anti-inflammatory, anticancer, anti-oxidative function. The aim this study was to investigate whether PHL could ameliorate high glucose-mediated oxidation, hypertrophy, fibrosis H9c2 cells...
AimsThe purpose of this study was to investigate the functional role G-protein-coupled inward rectifier potassium (GIRK) channels in cardiac ventricle.
Extracellular matrix (ECM) exerts a series of biological functions and contributes to almost 30% the osteogenic process. Periostin is secreted protein that can alter ECM remodeling in response vascular injury. However, role periostin calcification has yet be fully investigated. As found this study, recombinant accelerated thoracic aortas calcification, increased expression glycolysis key enzymes, disturbed normal oxidative phosphorylation (OXPHOS) ex vivo, which could alleviated by...
In this paper, we propose a novel approach based on deep belief networks for features learning of ECG arrhythmias. The method consists four steps: signals preprocessing, segmentation and resampling, learning, validation. the resampling stage all segmented beats are changed into same periodic length model. For extracting data, use two types restricted boltzmann machine including Gaussian-Bernoulli Bernoulli-Bernoulli to construct netowrks. order enhance netowrks performance, fine-tuning...
G protein-coupled inwardly rectifying K⁺ channels (GIRK) are important in the regulation of heart rate and atrial electrophysiology. GIRK activated by receptors, including muscarinic M₂ receptors adenosine A₁ receptors. The aim this study was to characterize compare electrophysiological effects acetylcholine (ACh) on rat atria. Action potential duration at 90% repolarization (APD₉₀), effective refractory period (ERP), resting membrane (RMP) were investigated isolated atria intracellular...
Brain-derived neurotrophic factor (BDNF) plays a functional role in vascular endothelium homeostasis and the alleviation of atherosclerosis. Matrix gla protein (MGP) Nε-(1-carboxymethyl)-l-lysine (CML) are both confirmed to be VC predictors. This study investigated association between BDNF, MGP, CML coronary artery calcification (CAC). Plasma levels were measured 274 patients who underwent computed tomography determine CAC score (Agatston score). It was found that with exhibited lower BDNF...
GENERAL COMMENTARY article Front. Med., 08 April 2024Sec. Intensive Care Medicine and Anesthesiology Volume 11 - 2024 | https://doi.org/10.3389/fmed.2024.1353046
Objective To study the dynamic changes of Hepcidin-25 in different disease process patients with multiple myeloma (MM) and its relationship therapeutic effect prognosis.Methods The expression levels 54 MM were analyzed by RT-PCR ELISA.The correlations between patients' clinical manifestations,clinical predictive value prognosis researched.Results Expressions mRNA protein significantly higher than those normal control group [0.58±0.19 vs 0.08±0.027,P =0.001,(5.2±11.9) ng/ml (22.5±7.1) ng/ml,P...
A 4-year-old child with β-thalassemia major underwent allogeneic hematopoietic stem cell transplantation (HSCT) on August 30, 2022 from a male haploidentical donor. He developed massive pericardial effusion (PE) secondary to pulmonary infection. Methylprednisolone, tacrolimus discontinued, and pericardiocentesis were all ineffective. Since the interleukin-6 (IL-6) level in PE was markedly increased (1868.58pg/ml), total of two doses tocilizumab administered intravenously at dosage 5mg/kg...
Abstract Introduction: Pregnant women with pre-excitation syndrome are more likely to develop supraventricular tachycardia (SVT) during pregnancy and delivery, leading an increased risk of adverse events. Method This was a retrospective study 309 pregnancies in 280 (29 had two this series) who delivered at West China Second University Hospital from June 2011 October 2021. All the recruited pregnant were divided into SVT non-SVT groups analyze cardiac obstetric complications. Results Among...